Zobrazeno 1 - 10
of 109
pro vyhledávání: '"T. S. Ingebritsen"'
Autor:
Bhanu P. Jena, S. Jakes, T. S. Ingebritsen, J. Richards, Louisa B. Tabatabai, Bonnie L. Beck, K. L. Hippen
Publikováno v:
Biochemistry. 32:12405-12412
The mechanisms for substrate recognition by two cytoplasmic protein tyrosine phosphatases, PTP-5 and rrbPTP-1, were investigated. Phosphorylation sites on tyrosine-phosphorylated casein, a model PTP substrate, were characterized. Two peptides based o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff22be151d8621db2f26b86ba12b3f7
https://doi.org/10.1021/bi00097a019
https://doi.org/10.1021/bi00097a019
Publikováno v:
Journal of Biological Chemistry. 266:10043-10046
pp54 microtubule-associated protein-2 (MAP-2) kinase, a recently discovered protein serine/threonine kinase (Kyriakis, J., and Avruch, J. (1990) J. Biol. Chem. 265, 17355-17363), is shown to contain immunoreactive phosphotyrosine residues. Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5002cc663616334864fda30cb2bec6
https://doi.org/10.1016/s0021-9258(18)99183-0
https://doi.org/10.1016/s0021-9258(18)99183-0
Publikováno v:
Journal of Biological Chemistry. 266:17744-17746
Eukaryotic cells respond to various stimuli by an increase or decrease in levels of phosphoproteins. Phosphotyrosine levels on eukaryotic cellular proteins are tightly regulated by the opposing actions of protein-tyrosine kinases and protein-tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b97d40621ea95073f477f150d9442f
https://doi.org/10.1016/s0021-9258(18)55188-7
https://doi.org/10.1016/s0021-9258(18)55188-7
Autor:
John H. Connor, Lifang Zhang, Shogo Endo, Ernest Y.C. Lee, B. Forney, S. Shenolikar, T. S. Ingebritsen
Publikováno v:
Biochemistry. 36(23)
The phosphorylase phosphatase activity of protein phosphatase 1 (PP1) catalytic subunit from freshly purified rabbit skeletal muscle was inhibited by MnCl2. Prolonged storage or inhibition by nonspecific phosphatase inhibitors ATP, sodium pyrophospha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e554f9648d89b2ac0cdd5f413f4f198e
https://pubmed.ncbi.nlm.nih.gov/9188695
https://pubmed.ncbi.nlm.nih.gov/9188695
Publikováno v:
Analytical biochemistry. 223(1)
Thiophosphotyrosyl protein and peptide substrate analogs were found to be potent and specific protein-tyrosine phosphatase inhibitors with IC50s in the range of 0.2-30 microM. The analogs were based on highly reactive substrates and included thiophos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a07f1eabf38ee0d98297044afbd10b3
https://pubmed.ncbi.nlm.nih.gov/7718049
https://pubmed.ncbi.nlm.nih.gov/7718049
Publikováno v:
The Journal of biological chemistry. 266(16)
pp54 microtubule-associated protein-2 (MAP-2) kinase, a recently discovered protein serine/threonine kinase (Kyriakis, J., and Avruch, J. (1990) J. Biol. Chem. 265, 17355-17363), is shown to contain immunoreactive phosphotyrosine residues. Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eba0b12d3e65d78ba1f61c54523fcaf3
https://pubmed.ncbi.nlm.nih.gov/1645334
https://pubmed.ncbi.nlm.nih.gov/1645334
Autor:
T S, Ingebritsen
Publikováno v:
Methods in enzymology. 201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba7976be14e8893f213bd69916caeba8
https://pubmed.ncbi.nlm.nih.gov/1943773
https://pubmed.ncbi.nlm.nih.gov/1943773
Publikováno v:
Biochemistry. 27:3216-3222
DNA topoisomerase I has been purified to electrophoretic homogeneity from ovaries of the frog Xenopus laevis. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the most purified fraction revealed a single major band at 110 kDa and less abu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1ee32bbe45ac805fe6525db6e35b82
https://doi.org/10.1021/bi00409a014
https://doi.org/10.1021/bi00409a014
Autor:
T S Ingebritsen
Publikováno v:
Journal of Biological Chemistry. 264:7754-7759
Two Tyr-protein phosphatase inhibitors, termed inhibitor H (Mr greater than 500,000) and inhibitor L (Mr 38,000), have been detected in bovine brain extracts. The inhibitors were partially purified by chromatography on DEAE-cellulose and Sephacryl S-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c439bd1aeaa65969520956235c70951
https://doi.org/10.1016/s0021-9258(18)83299-9
https://doi.org/10.1016/s0021-9258(18)83299-9
Publikováno v:
Biochemistry. 28:415-419
Rod cell outer segments were found to contain a protein phosphatase activity toward phosphoopsin with properties very similar to those of protein phosphatase 1 or 2A. The opsin phosphatase activity was stable to ethanol precipitation, had a Mr of 35,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea0b63cf3a776a583a45d51318cacb1
https://doi.org/10.1021/bi00428a001
https://doi.org/10.1021/bi00428a001