Zobrazeno 1 - 10
of 100
pro vyhledávání: '"T. S. Benedict"'
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36818 (2012)
Hepatitis B virus (HBV) is a major etiological factor of hepatocellular carcinoma (HCC). However, the precise pathogenetic mechanisms linking HBV infection and HCC remain uncertain. It has been reported that decreased antioxidant enzyme activities ar
Externí odkaz:
https://doaj.org/article/2112ca7e01d74f17aac5cf7e3d2fdde3
Autor:
Bing Na, Zhiming Huang, Qian Wang, Zhongxia Qi, Yongjun Tian, Cheng-Chan Lu, Jingwei Yu, Martha A Hanes, Sanjay Kakar, Eric J Huang, J-H James Ou, Limin Liu, T S Benedict Yen
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26240 (2011)
Hepatocellular carcinoma (HCC), the third leading cause of cancer deaths worldwide, is most commonly caused by chronic hepatitis B virus (HBV) infection. However, whether HBV plays any direct role in carcinogenesis, other than indirectly causing chro
Externí odkaz:
https://doaj.org/article/964ffadd64f644ad9be7b9f37484f483
Autor:
Li, Bin, Yen, T. S. Benedict ‡
Publikováno v:
In Journal of Biological Chemistry 22 March 2002 277(12):10306-10314
Publikováno v:
Human Oncogenic Viruses. :335-339
Publikováno v:
Human Oncogenic Viruses. :i-xiv
Publikováno v:
Molecular and Cellular Biology. 25:7522-7533
IRE1-alpha is an integral membrane protein of the endoplasmic reticulum (ER) that is a key sensor in the cellular transcriptional response to stress in the ER. Upon induction of ER stress, IRE1-alpha is activated, resulting in the synthesis of the ac
Publikováno v:
Proceedings of the National Academy of Sciences. 102:4120-4125
Knockout studies have shown that the transcription factor Nrf1 is essential for embryonic development. Nrf1 has been implicated to play a role in mediating activation of oxidative stress response genes through the antioxidant response element (ARE).
Autor:
Owen T. M. Chan, T. S. Benedict Yen, Gail Cassafer, Seth Brindis, Elizabeth Kaufman, David I. Daikh, Gaye Cunnane
Publikováno v:
Arthritis & Rheumatism. 50:1539-1548
Objective To compare the effects of combined administration of cyclophosphamide (CYC) and CTLA-4Ig with the effects of these agents alone on the immunopathology and progression of renal damage in (NZB × NZW)F1 (B/W) lupus-prone mice, and to explore
Autor:
T. S. Benedict Yen, Bin Li
Publikováno v:
Journal of Biological Chemistry. 277:10306-10314
The polypyrimidine tract-binding protein (PTB) is a nuclear protein that regulates alternative splicing. In addition, it plays a role in the cytoplasm during infection by some viruses and functions as a positive effector of hepatitis B virus RNA expo