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Autor:
Bernd Meibohm, Josiah T. Ryman
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology. 6:576-588
Monoclonal antibodies (mAbs) have developed in the last two decades into the backbone of pharmacotherapeutic interventions in a variety of indications, with currently more than 40 mAbs approved by the US Food and Drug Administration, and several doze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::903c931c5131ad79e64e1a912fadaafe
https://doi.org/10.1002/psp4.12224
https://doi.org/10.1002/psp4.12224
Autor:
Josiah T, Ryman, Bernd, Meibohm
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Monoclonal antibodies (mAbs) have developed in the last two decades into the backbone of pharmacotherapeutic interventions in a variety of indications, with currently more than 40 mAbs approved by the US Food and Drug Administration, and several doze
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fbef6f12d629a447120989ded6e6746
https://pubmed.ncbi.nlm.nih.gov/28653357
https://pubmed.ncbi.nlm.nih.gov/28653357
Autor:
Theingi M. Thway, Narendra Chirmule, Bernd Meibohm, Vibha Jawa, Lei Zhou, Josiah T. Ryman, Jonathan Herskovitz, Stephanie A. Lee
Publikováno v:
The AAPS journal. 19(2)
In the clinical setting, anti-drug antibodies (ADA) against biotherapeutics can influence patient safety and interfere with product efficacy. High immunogenicity has been addressed in clinic by concomitant immune suppression, such as co-administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907934bfe5ee766b6097a25d78f2ff94
https://pubmed.ncbi.nlm.nih.gov/28070711
https://pubmed.ncbi.nlm.nih.gov/28070711
Autor:
Bernd Meibohm, Josiah T. Ryman, Sumit Rawal, Honghui Zhou, Margaret M. S. Thomson, Christine Li, Chetan Rathi, Dora B. Madhura, Ashit Trivedi, Wararat Limothai, Simone Kasek, Jocelyn H. Leu
Publikováno v:
Pharmaceutical Sciences Encyclopedia
This article presents a compilation of drug-drug interaction monographs involving therapeutic biologics. These include important “theoretical” drug-drug interactions along with well-established plausible mechanisms. These monographs are intended
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac78bdb28035cb0b22c2aa179f86f213
https://doi.org/10.1002/9780470571224.pse487
https://doi.org/10.1002/9780470571224.pse487
Publikováno v:
Acta Physiologica Scandinavica. 155:257-266
Relaxant effects of acetylcholine (ACh), histamine, calcitonin gene-related peptide (CGRP) and the calcium ionophore A23187 were examined in rat femoral (phi approximately 0.2 mm), mesenteric (0.2 mm), intrarenal (0.2 mm) and hepatic (0.3 mm) arterie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd32731fec5609232a9419147d2da0
https://doi.org/10.1111/j.1748-1716.1995.tb09972.x
https://doi.org/10.1111/j.1748-1716.1995.tb09972.x
Publikováno v:
American journal of veterinary research. 72(10)
Objective—To determine the pharmacokinetics after oral administration of a single dose of ponazuril to healthy llamas. Animals—6 healthy adult llamas. Procedures—Ponazuril (20 mg/kg) was administered once orally to 6 llamas (day 0). Blood sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e191b6f5421858c267ae6e058dc9679f
https://pubmed.ncbi.nlm.nih.gov/21962282
https://pubmed.ncbi.nlm.nih.gov/21962282
Publikováno v:
Acta Physiologica Scandinavica. 149:467-474
Enhancement of the extracellular potassium ion (K+) concentration combined with endothelial injury have been suggested to occur during cerebral ischaemia-reperfusion and vasospasm after subarachnoid hemorrhage. The effect of potassium (K+) depolariza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760d09fbe338d84bbaa63dd7f7f0eb24
https://doi.org/10.1111/j.1748-1716.1993.tb09644.x
https://doi.org/10.1111/j.1748-1716.1993.tb09644.x
Publikováno v:
Journal of public health (Oxford, England). 32(1)
Background This evaluation was undertaken in 2005, in the African region, to better understand the reaching every district (RED) implementation process that provides a framework for strengthening immunization services at the district level. Methods I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb69e983706bf5d16e6d81a48d7d0448
https://pubmed.ncbi.nlm.nih.gov/19542268
https://pubmed.ncbi.nlm.nih.gov/19542268
Publikováno v:
Journal of human hypertension. 9(4)
In this multicentre, randomised, double-blind, cross-over study, we evaluated and compared the effects of nitrendipine (a calcium entry blocker of the dihydropyridine group) and mefruside (a diuretic) on BP, cardiac output, cerebral blood flow and me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82ae0a267108843a486a886aebfbb39d
https://pubmed.ncbi.nlm.nih.gov/7595911
https://pubmed.ncbi.nlm.nih.gov/7595911