Zobrazeno 1 - 10
of 19
pro vyhledávání: '"T. Rupniak"'
Autor:
B.H. Anderton, J.-P. Brion, A-M. Couck, D.R. Davis, J.-M. Gallo, D.P. Hanger, K. Ladhani, D.A. Latimer, C. Lewis, S. Lovestone, B. Marquardt, C.C.J. Miller, S.F.C. Mulot, C.H. Reynolds, T. Rupniak, C.J. Smith, S. Stabel, J. Woodgett
Publikováno v:
Scopus-Elsevier
Two cellular systems have been used to investigate the modulation of tau hyperphosphorylation. In the first system, the effects of the excitatory amino acid glutamate, the microtubule destabilising agent colchicine, and beta 25-35-amyloid peptide on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::555b18e910d243973739971a7c9f3a45
https://doi.org/10.1016/0197-4580(94)00160-3
https://doi.org/10.1016/0197-4580(94)00160-3
Autor:
Andrew Makoff, Susan Chapman, Paul W. Sheppard, Claire L. Pollard, Amritpal Mudher, Abdur-Rasheed Asuni, L Raymond, Patrick A. Lewis, J Richardson, H T Rupniak, Todd E. Golde, Richard Killick, Brian H. Anderton, E Gower, Simon Lovestone, G M Gibb, T Iqbal, Matthew C. Murphy, Ian M. Varndell, P E Soden
Publikováno v:
Scopus-Elsevier
Alzheimer's disease (AD) is a disorder of two pathologies: amyloid plaques, the core of which is a peptide derived from the amyloid precursor protein (APP), and neurofibrillary tangles composed of highly phosphorylated tau. Protein kinase C (PKC) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26097ca1fd751feb26abfe3664db298
https://europepmc.org/articles/PMC6762860/
https://europepmc.org/articles/PMC6762860/
Autor:
D R Davis, J P Brion, A M Couck, J M Gallo, D P Hanger, K Ladhani, C Lewis, C C J Miller, T Rupniak, C Smith, B H Anderton
Publikováno v:
Scopus-Elsevier
The effects of the excitatory amino acid glutamate, the microtubule destabilizing agent colchicine, and beta 25-35-amyloid peptide on the phosphorylation state of tau were studied in rat cortical neurons in primary culture. Using immunocytochemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2cc1f799a60f87fb9b339f1820704c1
https://pubmed.ncbi.nlm.nih.gov/7639714
https://pubmed.ncbi.nlm.nih.gov/7639714
Autor:
J-M. Gallo, K Ladhani, C. Lewis, J-P. Brion, Charles D. Smith, D R Davis, D.P. Hanger, B.H. Anderton, A-M. Couck, Christopher C.J. Miller, T. Rupniak
Publikováno v:
Neurobiology of Aging. 15:S25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8d6ae3d9ba5ea116836885618083c7f
https://doi.org/10.1016/0197-4580(94)92557-7
https://doi.org/10.1016/0197-4580(94)92557-7
Publikováno v:
International journal of cancer. 32(1)
Cryopreserved tumour cells obtained from the ascitic fluid of a patient with an ovarian carcinoma were employed to determine the effect on in vitro drug cytotoxicities of varying both drug concentration and exposure time. Four antitumour drugs, in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44612999a67ac0e53f9dc0cf79d273f
https://pubmed.ncbi.nlm.nih.gov/6683250
https://pubmed.ncbi.nlm.nih.gov/6683250
Autor:
H. T. Rupniak, Denise Sheer, S.A. Shellard, Richard D. H. Whelan, Louise K. Hosking, Bridget T. Hill, Elizabeth M. Gibby
Publikováno v:
International journal of cancer. 39(2)
Three new human cell lines have been established from biopsy specimens of ovarian cystadenocarcinomas: line JA-1 was derived from a primary "solid" tumour from an untreated patient, whilst the other lines were derived from ascites from patients previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcfc1443cec4f96309177ca6156e136
https://pubmed.ncbi.nlm.nih.gov/3804493
https://pubmed.ncbi.nlm.nih.gov/3804493
Publikováno v:
Cancer research. 45(11 Pt 2)
Cell lines from six human squamous cell carcinomas exhibiting different degrees of differentiation and malignancy were studied under in vitro and in vivo growth conditions. The stability of phenotypic traits of these carcinoma cells and their sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6670dfdca3288f949a35cc13251c5ea6
https://pubmed.ncbi.nlm.nih.gov/4053033
https://pubmed.ncbi.nlm.nih.gov/4053033
Autor:
H T, Rupniak, C, Rowlatt, E B, Lane, J G, Steele, L K, Trejdosiewicz, B, Laskiewicz, S, Povey, B T, Hill
Publikováno v:
Journal of the National Cancer Institute. 75(4)
Four human cell lines were established from biopsy specimens of squamous cell carcinomas of the larynx (TR131 and TR138), tongue (TR126), and buccal mucosa that had infiltrated a lymph node (TR146). All 4 lines readily formed colonies on a plastic su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d534b83e095c0c023eedf1df32baab9
https://pubmed.ncbi.nlm.nih.gov/2413234
https://pubmed.ncbi.nlm.nih.gov/2413234
Publikováno v:
Archiv fur Geschwulstforschung. 51(1)
The value of certain concepts derived from experimental studies of stem cell kinetics are discussed in terms of their clinical relevance. The application of these principles involving treatment for approximately 24 hours on an intermittent basis as s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f20f05982366f1872a54815bda9c2791
https://pubmed.ncbi.nlm.nih.gov/7259432
https://pubmed.ncbi.nlm.nih.gov/7259432
Autor:
H T, Rupniak, D, Paul
Publikováno v:
Cancer research. 40(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eec44d51af8a7e2e7f80bd4718eabd27
https://pubmed.ncbi.nlm.nih.gov/6243249
https://pubmed.ncbi.nlm.nih.gov/6243249