Výsledky vyhledávání - "T. Rossmanith"

Rituximab plus leflunomide in rheumatoid arthritis: a randomized, placebo-controlled, investigator-initiated clinical trial (AMARA study)

Autor: Andrea Rubbert-Roth, Hans-Peter Tony, Harald Burkhardt, Martin Aringer, Klaus Krueger, Ulf Müller-Ladner, T. Rossmanith, Michaela Koehm, Marina Backhaus, Rieke Alten, Eva Herrmann, Annette Lehn, Eugen Feist, Frank Behrens, Siegfried Wassenberg, Herbert Kellner, Gerd R Burmester

Publikováno v: Rheumatology (Oxford, England)

Objective To investigate the efficacy and safety of rituximab + LEF in patients with RA. Methods In this investigator-initiated, randomized, double-blind, placebo-controlled phase 3 trial, patients with an inadequate response to LEF who had failed on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb210b4686b2ac48c90aa765fd72941e
http://europepmc.org/articles/PMC8566251

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A data science approach to the selection of most informative readouts of the human intradermal capsaicin pain model to assess pregabalin effects

Autor: Miriam Wolters, Martin Zunftmeister, T. Rossmanith, Gerd Geisslinger, Carmen Walter, Bruno G. Oertel, Jörn Lötsch, Nerea Ferreirós, Sebastian Zinn

Publikováno v: Basic & Clinical Pharmacology & Toxicology. 126:318-331

Persistent and, in particular, neuropathic pain is a major healthcare problem with still insufficient pharmacological treatment options. This triggered research activities aimed at finding analgesics with a novel mechanism of action. Results of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01809f01ab6f3543e8b38543b00a03ac
https://doi.org/10.1111/bcpt.13337

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POS1059 EFFICACY OF UST IN ACTIVE PsA IS INDEPENDENT FROM CONCOMITANT MTX USE, EVEN IN PATIENTS WITH MORE SEVERE SKIN PSORIASIS: SUBGROUP ANALYSIS FROM A RANDOMIZED PLACEBO-CONTROLLED INVESTIGATOR INITIATED CLINICAL TRIAL

Autor: M. Köhm, T. Rossmanith, A. C. Foldenauer, H. Kellner, U. Kiltz, J. Rech, G. R. Burmester, D. M. Kofler, J. Brandt-Juergens, C. Jonetzko, H. Burkhardt, F. Behrens

Publikováno v: Annals of the Rheumatic Diseases. 81:850.2-851

BackgroundThe use of bDMARDs treatments in patients with psoriatic arthritis (PsA) usually requires treatment failure or intolerance of csDMARD/MTX before initiation. The value of MTX in combination with bDMARDs is still unclear. We designed an inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc036f6c46cb819b5bc896401115261d
https://doi.org/10.1136/annrheumdis-2022-eular.3929

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POS1094 CORRELATION OF FLUORESCENCE-OPTICAL IMAGING AND PHYSICIAN TJC/SJC ASSESSMENT AND ULTRASOUND IN PSORIASIS PATIENTS WITHOUT ARTHRITIS BUT MUSCULOSKELETAL COMPLAINTS WITHIN THE LAST 6 MONTHS

Autor: M. Köhm, S. Ohrndorf, X. Baraliakos, K. Hallmann, S. Kempinski, A. C. Foldenauer, T. Rossmanith, U. Henkemeier, F. Behrens

Publikováno v: Annals of the Rheumatic Diseases. 81:874.1-874

BackgroundPsoriasis (PsO) is one of the most common chronic inflammatory skin diseases in Europe. Psoriatic arthritis (PsA) is closely associated to PsO; up to 40% of PsO patients develop PsA. The transition from PsO to PsA includes different stages

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b82fe88fa054367ae726e968ee3c62ce
https://doi.org/10.1136/annrheumdis-2022-eular.3987

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Predictive PBPK modeling as a tool in the formulation of the drug candidate TMP-001

Autor: T. Rossmanith, Mukul Ashtikar, Matthias G. Wacker, Gerd Geisslinger, Lisa Nothnagel, Michael J. Parnham, Fabian Jung, Manuela Thurn

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics. 134:144-152

Since many drugs in the therapy scheme of multiple sclerosis (MS) are applied parenterally with significant side effects, oral treatment is the most accepted therapy option for chronic diseases like MS. The drug candidate TMP-001, which has disease-m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b987ac27bafbedd809cb00b3afaf42
https://doi.org/10.1016/j.ejpb.2018.11.012

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OP0121 PATIENT CHARACTERISTICS AND INCIDENCE OF SIGNS OF INFLAMMATION IN PATIENTSWITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS AND POSITIVE ANTI-CITRULLINATED PEPTIDE POINT-OF-CARE TEST IN GERMANY – THE PANORA TRIAL

Autor: Karola Mergenthal, Frank Behrens, Juliana J. Petersen, T. Rossmanith, U. Henkemeier, Harald Burkhardt, Michaela Koehm

Publikováno v: Oral Presentations.

Background Rheumatoid Arthritis (RA) is a chronic inflammatory joint disease affecting approx. 1% of the adult population of Northern Europe. Strategies for its early detection and diagnosis are of high importance as prompt treatment improves clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11bccdcfb09d194b26dd27d59c4c5641
https://doi.org/10.1136/annrheumdis-2019-eular.4833

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Akademický článek

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AB1111 PREDICTIVE VALUE OF FLUORESCENCE-OPTICAL IMAGING TECHNIQUE IN DETECTION OF PSORIATIC ARTHRITIS IN PSORIASIS PATIENTS

Autor: T. Rossmanith, Marina Backhaus, M. Köhm, Harald Burkhardt, G.-R. Burmester, B. Köhler, Sarah Ohrndorf, Siegfried Wassenberg, Frank Behrens

Publikováno v: Annals of the Rheumatic Diseases. 79:1845.1-1845

Background:Psoriasis (Pso) is one of the most common chronic inflammatory skin diseases in Europe. Psoriatic arthritis (PsA) is closely associated to Pso whereas the skin manifestation appears usually years before PsA-related symptoms emerge. Up to 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ab20e963088fdebd64a904a9d11297e7
https://doi.org/10.1136/annrheumdis-2020-eular.5300

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SAT0032 INCIDENCE OF RHEUMATOID ARTHRITIS IN PATIENTS WITH NEW ONSET OF MUSCULOSKELETAL SYMPTOMS AND ANTI-CPP POSITIVITY COMPARED TO ANTI-CPP NEGATIVE PATIENTS

Autor: Juliana J. Petersen, Karola Mergenthal, T. Oberwahrenbrock, Frank Behrens, Harald Burkhardt, S. Dauth, M. Köhm, T. Rossmanith, U. Henkemeier

Publikováno v: Annals of the Rheumatic Diseases. 79:946.1-946

Background:Rheumatoid Arthritis (RA) is a chronic inflammatory joint disease. Strategies for its early detection and diagnosis are of high importance as prompt treatment improves clinical and structural outcome. Autoantibodies against cyclic citrulli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d21e5ec6634b0564a3eb41091af5d024
https://doi.org/10.1136/annrheumdis-2020-eular.5463

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