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Publikováno v:
Medical Physics. 39:2997-3008
Purpose: To describe a novel methodology of converting megavoltage x-ray projections into virtual proton projections that are otherwise missing due to the proton range limit. These converted virtual proton projections can be used in the reconstructio
Publikováno v:
Medical Physics. 37:4138-4145
Purpose: To describe a method to estimate the proton path in proton computed tomography (pCT) reconstruction, which is based on the probability of a proton passing through each point within an object to be imaged. Methods: Based on multiple Coulomb s
Autor:
Rick Chappell, Michelle Turek, Jessica Lawrence, Richard R. Dubielzig, Hazim Jaradat, T. Rockwell Mackie, Lisa J. Forrest, Minesh P. Mehta, Paul E. Miller, David M. Vail
Publikováno v:
Veterinary Radiology & Ultrasound. 51:561-570
Intensity-modulated radiation therapy (IMRT) allows optimization of radiation dose delivery to complex tumor volumes with rapid dose drop-off to surrounding normal tissues. A prospective study was performed to evaluate the concept of conformal avoida
Publikováno v:
Physics in Medicine and Biology. 53:4153-4167
In this work the abilities of intensity modulated x-ray therapy (IMXT) and intensity modulated proton therapy (IMPT) to deliver boosts based on theragnostic imaging were assessed. Theragnostic imaging is the use of functional or molecular imaging dat
Publikováno v:
Veterinary Radiology Ultrasound. 47:228-233
A primary lung tumor in a dog treated with intensity-modulated radiation therapy was imaged approximately 6 weeks and 1-year posttreatment with combined positron emission tomography (PET) and computed tomography, utilizing the radiotracers 18F-fluoro
Publikováno v:
Medical Physics. 32:2346-2350
The interplay between a constant scan speed and intrafraction oscillatory motion produces interesting fluence intensity modulations along the axis of motion that are sensitive to the motion function, as originally shown in a classic paper by Yu et al
Publikováno v:
Medical Physics. 31:2412-2415
Deformable image registration is an important tool for image-guided radiotherapy. Physics-model-based deformable image registration using finite element analysis is one of the methods currently being investigated. The calculation accuracy of finite e
Publikováno v:
Physics in Medicine and Biology. 48:1141-1152
Practical contemporary radiotherapy dosimetry systems used for dose measurement and verification are ionization chambers (which typically have at least a 0.1 cm3 air cavity volume), thermoluminescent dosimeters (TLDs) and silicon diodes. However, dur
Autor:
Minesh P. Mehta, Paul M. Harari, James S. Welsh, Mark A. Ritter, Rakesh R. Patel, T. Rockwell Mackie
Publikováno v:
Technology in Cancer Research & Treatment. 1:311-316
Helical tomotherapy represents both a novel radiation treatment device and an innovative means of delivering radiotherapy. The helical tomotherapy unit itself is essentially a hybrid between a linear accelerator and a helical CT scanner for the purpo