Výsledky vyhledávání - "T. Robert Ju"

Effect of formulation variables on drug and polymer release from HPMC-based matrix tablets

Autor: Ping Gao, K.C. Sung, Patel Mahest, T. Robert Ju, John W. Skoug, Phillip R. Nixon, Elizabeth M. Topp

Publikováno v: International Journal of Pharmaceutics. 142:53-60

The objective of this work was to assess the effect of two formulation variables, hydroxypropylmethylcellulose (HPMC)/lactose ratio and HPMC viscosity grade, on the release of a model drug and HPMC, as well as the mechanism of drug release from HPMC-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4386cfb97f9291fb3eaaabb8e7abe9ce
https://doi.org/10.1016/0378-5173(96)04644-3

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Swelling of hydroxypropyl methylcellulose matrix tablets. 2. Mechanistic study of the influence of formulation variables on matrix performance and drug release

Autor: Ping Gao, Kuo-Chun Sung, T. Robert Ju, Phillip R. Nixon, Nick L. Stemm, John W. Skoug

Publikováno v: Journal of pharmaceutical sciences. 85(7)

We characterized the effect of hydroxypropyl methylcellulose (HPMC)/lactose ratio and HPMC viscosity grade (molecular weight) on solute release and swelling of matrix tablets. We used a semiquantitative optical imaging method to monitor the swelling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc460cd6bd2a9d09b37b30c2a83cdf7c
https://pubmed.ncbi.nlm.nih.gov/8818998

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