Epithelial barrier dysfunctions in atopic dermatitis: a skin-gut-lung model linking microbiome alteration and immune dysregulation

Autor: Raja K Sivamani, T. H. Zhu, T. R. Zhu, Khiem Tran, Vivian Y. Shi

Publikováno v: British Journal of Dermatology. 179:570-581

Background Atopic dermatitis is a systemic disorder characterized by abnormal barrier function across multiple organ sites. Causes of epidermal barrier breakdown are complex and driven by a combination of structural, genetic, environmental and immuno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ee953b750eb6eaa655cbc35c755f8d1
https://doi.org/10.1111/bjd.16734

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

Autor: Robert B. Norgren, Jacob D. Estes, Krystelle Nganou Makamdop, Richard T R Zhu, Daniel C. Douek, Brenna J. Hill, Steven E. Bosinger, Eli Boritz, Gregory Q. Del Prete, Samuel Darko, Emma Reiss, Jeffrey D. Lifson, Ganit Yarden, Jerome A. Langer, Brandon F. Keele, Srinivas S. Rao, Guido Silvestri, J. Katherina Timmer, Eduardo J. Contijoch, Doron Levin, John Paul Todd, Sathi Wijeyesinghe, Martha Nason, Gideon Schreiber, Gregory K. Tharp, Netanya G. Sandler

Publikováno v: Nature. 511(7511)

The timing of type I interferon signalling determines the disease course of SIV infection. Type I interferon (IFN-I) is shown here to have dual effects in rhesus macaques exposed to simian immunodeficiency virus (SIV): it is beneficial at the onset o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3a1b028d3a6cf60dbf2f43a6dedf2d
https://pubmed.ncbi.nlm.nih.gov/25043060

Harnessing myelin water fraction as an imaging biomarker of human cerebral aging, neurodegenerative diseases, and risk factors influencing myelination: A review.

Autor: Faulkner ME; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Gong Z; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Guo A; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Laporte JP; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Bae J; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Bouhrara M; Laboratory of Clinical Investigation, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.

Publikováno v: Journal of neurochemistry [J Neurochem] 2024 Sep; Vol. 168 (9), pp. 2243-2263. Date of Electronic Publication: 2024 Jul 08.

[The isolation and identification of qianhucoumarin B and qianhucoumarin C from Peucedanum praeruptorum]

Autor: L Y, Kong, Y H, Pei, X, Li, S X, Wang, B L, Hou, T R, Zhu

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 28(10)

Five compounds were isolated from the traditional Chinese medicine Qianhu, roots of Peucedanum praeruptorum. Their structures were identified as 3'-angeloyloxykhellactone (IX), qianhucoumarin B (X), qianhucoumarin C (XI), Pd-III (XIII) and peucedanoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ddd925dbc18f1993222b8b8cb8a277d6
https://pubmed.ncbi.nlm.nih.gov/8009990

[Studies on naphthoic acid esters from the roots of Rubia cordifolia L]

Autor: H M, Hua, S X, Wang, L J, Wu, X, Li, T R, Zhu

Publikováno v: Yao xue xue bao = Acta pharmaceutica Sinica. 27(4)

Four naphthoic acid esters including a new compound were isolated from the roots of Rubia cordifolia L. The new one was named as rubilactone and its structure was elucidated as 3'-carbomethoxy-4'-hydroxy-naphtho[1',2'-2,3] pyran-6-one (I) based on th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8b1a6edf02c06c2e585dcee8e6cd525a
https://pubmed.ncbi.nlm.nih.gov/1442042