Výsledky vyhledávání - "T. R. Winters"

ras isoprenylation is required for ras-induced but not for NGF-induced neuronal differentiation of PC12 cells

Autor: T. R. Winters, Meng-Sheng Qiu, Steven H. Green, A. F. Pitts

Publikováno v: The Journal of Cell Biology

We have used compactin, an inhibitor of mevalonate biosynthesis, to block p21ras posttranslational modification and membrane association in PC12 cells. Previous studies have demonstrated a requirement for isoprenylation for mitogenic effects of activ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0aa3ce6fc056d7746df5c8692be917
http://europepmc.org/articles/PMC2289192

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Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons

Autor: Steven H. Green, T. R. Winters, Peter W. Mesner

Publikováno v: The Journal of Cell Biology

Previous studies have shown that in neuronal cells the developmental phenomenon of programmed cell death is an active process, requiring synthesis of both RNA and protein. This presumably reflects a requirement for novel gene products to effect cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357c14e71786eaa578275de1c2b85f67
https://pubmed.ncbi.nlm.nih.gov/1469055

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