Výsledky vyhledávání - "T. R. Stiebel"

In vitro Sequential Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants with Reduced Sensitivity to Hydroxyethylurea Protease Inhibitors

Autor: Simon P. Tucker, W. C. Stallings, T. R. Stiebel, Karen E. Potts, Joseph J. McDonald, Mary Smidt, Martin L. Bryant

Publikováno v: Antiviral Chemistry and Chemotherapy. 8:447-456

In vitro resistance to the human immunodeficiency virus (HIV) protease inhibitors SC-52151 and SC-55389A was evaluated in an in vitro sequential selection scheme. HIVRF variants were selected for reduced sensitivity to SC-52151 and subsequently passa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f8c4d0804677bf0994220417f83322a
https://doi.org/10.1177/095632029700800508

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A mutation in human immunodeficiency virus type 1 protease at position 88, located outside the active site, confers resistance to the hydroxyethylurea inhibitor SC-55389A

Autor: L Blystone, D Pillay, Karen E. Potts, Martin L. Bryant, Simon P. Tucker, W. C. Stallings, Mary Smidt, T. R. Stiebel, D D Richman, Joseph J. McDonald

Publikováno v: Antimicrobial Agents and Chemotherapy. 41:515-522

The hydroxyethylurea human immunodeficiency virus type 1 (HIV-1) protease inhibitors SC-55389A and SC-52151 were used to select drug-resistant variants in vitro. One clinical HIV-1 strain (89-959) and one laboratory HIV-1 strain (LAI) were passaged i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16db6aa83e299a33a5a2349b4c436df3
https://doi.org/10.1128/aac.41.3.515

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Use of drug combinations for selection of human immunodeficiency virus type I (HIV-1) variants with decreased sensitivity to hydroxyethylurea isostere containing protease inhibitors in vitro

Autor: M.L. Smidt, Karen E. Potts, M.L. Bryant, T. R. Stiebel, W. C. Stallings, M. Clare, Simon P. Tucker

Publikováno v: Antiviral Research. 26:A256

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79e714179f94c2f8122bf9cee9def54e
https://doi.org/10.1016/0166-3542(95)94753-o

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