Zobrazeno 1 - 10
of 35
pro vyhledávání: '"T. R. Santhosh Kumar"'
Publikováno v:
International Journal of Nanomedicine. 17:5581-5600
Akhil K Mohan,1,2 Minsa M,3 T R Santhosh Kumar,3 G S Vinod Kumar1 1Nano Drug Delivery Systems (NDDS), Cancer Biology Division, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India; 2Research Centre, Department of Biotechno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c32a05a707f057296fcb5ad3e44458
https://doi.org/10.2147/ijn.s376358
https://doi.org/10.2147/ijn.s376358
Autor:
Vibin Ramakrishnan, Ruchika Goyal, Aneesh Chandrasekharan, Gaurav Jerath, Yvonne Christian, T. R. Santhosh Kumar
Publikováno v:
Drug Delivery and Translational Research. 12:1285-1292
A complete peptide-based drug delivery unit has been designed with a tumor homing domain chemically linked to a syndiotactic cell-penetrating domain. The designed peptides were synthesized, characterized, and tested in vitro for cellular uptake and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff60139ce88498150f5c09a98353e504
https://doi.org/10.1007/s13346-021-01035-z
https://doi.org/10.1007/s13346-021-01035-z
Autor:
Gaurav Jerath, Pramod Darvin, Yvonne Christian, Vishal Trivedi, T. R. Santhosh Kumar, Vibin Ramakrishnan
Publikováno v:
Molecular pharmaceutics. 19(8)
The utilization of peptide-based drug delivery systems has been suboptimal due to their poor proteolytic susceptibility, poor cell permeability, and limited tumor homing capabilities. Earlier attempts in using d-enantiomers in peptide sequences incre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f95e0d7e1ac68c47669ae3e203647455
https://pubmed.ncbi.nlm.nih.gov/35839086
https://pubmed.ncbi.nlm.nih.gov/35839086
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f03b3bff0426592c1a06a9de84730371
https://doi.org/10.1096/fasebj.2022.36.s1.0r421
https://doi.org/10.1096/fasebj.2022.36.s1.0r421
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132429 (2015)
Enhanced oxidative stress contributes to pathological changes in diabetes and its complications. Thus, strategies to reduce oxidative stress may alleviate these pathogenic processes. Herein, we have investigated Naringin mediated regulation of glutat
Externí odkaz:
https://doaj.org/article/96ebbd8b710c4923ae2bff802efe702b
Autor:
T. R. Santhosh Kumar, Chandramohan Krishnan Nair, Bharat Veerabhadran, Sanjeev Kulkarni, Madhu Muralee, Arun Peter Mathew, K M Jagathnath Krishna, Mira Sudam Waugh
Publikováno v:
Indian Journal of Surgery. 83:816-818
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4204b0007e847f9ec0d39dfc6521dc7
https://doi.org/10.1007/s12262-020-02332-6
https://doi.org/10.1007/s12262-020-02332-6
Autor:
Vikas Kumar, A Aneesh Kumar, T. R. Santhosh Kumar, Vinod Joseph, Abdul Jaleel, Vipin Mohan Dan, Chandrasekharan C Kartha
Publikováno v:
Molecular and Cellular Biochemistry. 463:147-160
Amalaki rasayana, a traditional preparation, is widely used by Ayurvedic physicians for the treatment of inflammatory conditions, cardiovascular diseases, and cancer. Metabolic alterations induced by Amalaki rasayana intervention are unknown. We inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27935dfdc902b01d22d01b0d0c9daa30
https://doi.org/10.1007/s11010-019-03637-1
https://doi.org/10.1007/s11010-019-03637-1
Publikováno v:
Molecular Biology Reports. 46:727-740
The current treatment system in cancer therapy, which includes chemotherapy/radiotherapy is expensive and often deleterious to surrounding healthy tissue. Presently, several medicinal plants and their constituents are in use to manage the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dee71b3d946435fa1301d32728c77b8b
https://doi.org/10.1007/s11033-018-4529-5
https://doi.org/10.1007/s11033-018-4529-5
Publikováno v:
Heart Failure Reviews. 24:255-267
Mitochondrial dysfunction is widely recognized as a major factor for the progression of cardiac failure. Mitochondrial uptake of metabolic substrates and their utilization for ATP synthesis, electron transport chain activity, reactive oxygen species
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a5e818519489f57969406bab836a1b
https://doi.org/10.1007/s10741-018-9756-2
https://doi.org/10.1007/s10741-018-9756-2
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100909-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100909-(2021)
Highlights • The cell-of-origin of early and late disseminating, metastatic clones determines tumor aggressiveness. • Cellular senescence and microenvironmental cues also promote collective invasion and acquired stemness as a dynamic state in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::584c3a683b153a8e1ee10f11fa89f4e3
https://pubmed.ncbi.nlm.nih.gov/33049522
https://pubmed.ncbi.nlm.nih.gov/33049522