Zobrazeno 1 - 10 of 55 pro vyhledávání: '"T. R. J. Lappin"'
1
An Urgent Need for Standardization of Stem Cells and Stem Cell-derived Products Toward Clinical Applications
Autor: Tao Cheng, T. R. J. Lappin
Publikováno v: Lappin, T & Cheng, T 2021, ' An Urgent Need for Standardization of Stem Cells and Stem Cell-derived Products Toward Clinical Applications ', Stem cells translational medicine, vol. 10, no. S2, pp. S1-S3 . https://doi.org/10.1002/sctm.21-0269
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss S2, Pp S1-S3 (2021)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f23361f9e479df38aad8f12c3cdc1eb0
https://pure.qub.ac.uk/en/publications/999d6227-f43a-46f2-8132-49f1f6885812
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2
GATA2 regulates the erythropoietin receptor in t(12;21) ALL
Autor: Vivien M. Hodges, Hilary A. A. Colyer, Ken I. Mills, James S. Smith, T. R. J. Lappin, Marie E. Gaine, Daniel J. Sharpe
Publikováno v: Gaine, M E, Sharpe, D J, Smith, J S, Colyer, H, Hodges, V M, Lappin, T R & Mills, K I 2017, ' GATA2 regulates the erythropoietin receptor in t(12;21) ALL ', Oncotarget, vol. 8, no. 39, pp. 66061-66074 . https://doi.org/10.18632/oncotarget.19792
Oncotarget
// Marie E. Gaine 1, 2, * , Daniel J. Sharpe 1, * , James S. Smith 1 , Hilary A.A. Colyer 1 , Vivien M. Hodges 1 , Terry R. Lappin 1 and Ken I. Mills 1 1 Centre for Cancer Research and Cell Biology, Queen’s University Belfast, Belfast BT9 7BL, Unit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cb503a3bed39f2be906616f4579f47
https://pure.qub.ac.uk/en/publications/gata2-regulates-the-erythropoietin-receptor-in-t1221-all(6032fbcd-a9ca-4ab9-ace3-bc58ac93bd98).html
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3
Sibling synergy
Autor: T. R. J. Lappin
Publikováno v: Stem cells translational medicine. 4(1)
The sister journals Stem Cells and Stem Cells Translational Medicine have synergistic roles, although there is often considerable overlap in content between them. Whereas Stem Cells is primarily concerned with advancing basic knowledge of mechanism a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7fb1e4987541ed14811bc02cafb0c86
https://pubmed.ncbi.nlm.nih.gov/25473083
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4
Disorders of oxidised haemoglobin
Autor: Melanie J. Percy, Neil V. McFerran, T. R. J. Lappin
Publikováno v: Blood Reviews. 19:61-68
Methaemoglobinaemia arises from the production of non-functional haemoglobin containing oxidised Fe(3+) which results in reduced oxygen supply to the tissues and manifests as cyanosis in the patient. It can develop by three distinct mechanisms: genet
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6746e18d3293c649a5f2b81da6c26acb
https://doi.org/10.1016/j.blre.2004.02.001
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5
The worldwide distribution of the VHL 598C>T mutation indicates a single founding event
Autor: Sanjay Shete, Sonny Ang, Enli Liu, Victor R. Gordeuk, Josef T. Prchal, T. R. J. Lappin, Yves D. Pastore, Yongli Guan, Melanie J. Percy, Mary Frances McMullin, Christopher I. Amos, David W. Stockton, Katerina Jedlickova, Lydia A. Polyakova
Publikováno v: Blood. 103:1937-1940
The first congenital defect of hypoxia-sensing homozygosity for VHL 598C>T mutation was recently identified in Chuvash polycythemia. Subsequently, we found this mutation in 11 unrelated individuals of diverse ethnic backgrounds. To address the questi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00de2b3a8132ea5af8050d3ce4b8c975
https://doi.org/10.1182/blood-2003-07-2550
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6
Study of maternal influences on fetal iron status at term using cord blood transferrin receptors
Autor: T R J Tubman, G.A. Savage, Henry L. Halliday, David G. Sweet, T R J Lappin
Publikováno v: Archives of Disease in Childhood - Fetal and Neonatal Edition. 84:40F-43
Aims—To determine eVects of maternal iron depletion and smoking on iron status of term babies using serum transferrin receptors (STfR) and their ratio to ferritin (TfR-F index) in cord blood. Methods—Iron, ferritin, STfR, and haemoglobin (Hb) con
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea7a75429cd1e46862a68d06e0af5ef4
https://doi.org/10.1136/fn.84.1.f40
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8
High bax expression is a good prognostic indicator in acute myeloid leukaemia
Autor: Alexandra E. Irvine, Mary Frances McMullin, F.G.C. Jones, T. R. J. Lappin, Y. L. Ong, K. E. M. Bailie
Publikováno v: British Journal of Haematology. 111:182-189
Most cytotoxic drugs kill cells by instigating the process of apoptosis and it has been suggested that apoptotic markers may provide an indication of tumour chemosensitivity. The aim of this study was to determine if such a relationship exists in acu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cc0498c277271660e50992aad2f310
https://doi.org/10.1046/j.1365-2141.2000.02315.x
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9
Erythropoietin production: evidence for multiple oxygen sensing pathways
Autor: Alexander P. Maxwell, G. E. Elder, G.A. Savage, T. R. J. Lappin, P. C. Winter, N. A. Daghman
Publikováno v: Annals of Hematology. 78:275-278
The production of erythropoietin (Epo), the glycoprotein hormone which controls red blood cell formation, is regulated by feedback mechanisms sensing tissue oxygenation. The mechanism of the putative oxygen sensor has yet to be elucidated. There is e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603867d28d0976a2b0dcaecdadcadc3c
https://doi.org/10.1007/s002770050514
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10
Regulation of Erythropoietin Gene Expression Depends on Two Different Oxygen-Sensing Mechanisms
Autor: S. Price, Alexander P. Maxwell, N. A. Daghman, Cliona M. McHale, T. R. J. Lappin, P. C. Winter, Gerard Savage
Publikováno v: Molecular Genetics and Metabolism. 67:113-117
Erythropoietin (Epo), a glycoprotein hormone produced principally in the fetal kidney and in the adult liver in response to hypoxia, is the prime regulator of growth and differentiation in erythroid progenitor cells. The regulation of Epo gene expres
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::778e792228335b02ab4478f6369aa7cb
https://doi.org/10.1006/mgme.1999.2851
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