Zobrazeno 1 - 10
of 14
pro vyhledávání: '"T. R. Hovsepyan"'
Autor:
I. S. Danielyan, N. S. Minasyan, R. E. Muradyan, A. A. Harutyunyan, A. S. Aharonyan, L. E. Nersesyan, T. R. Hovsepyan, M. R. Hakobyan
Publikováno v:
Russian Journal of Organic Chemistry. 56:2137-2142
While developing new approaches to the design of biologically active compounds based on 1,2,4-triazole, a number of new hydrazones containing pharmacologically active benzofuran, 5-methylbenzofuran, 1,2,4-triazole, pyridine, indole, and 1,3-benzodiox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d514285cf487137531b13d21e50e12a0
https://doi.org/10.1134/s1070428020120143
https://doi.org/10.1134/s1070428020120143
Publikováno v:
Russian Journal of Organic Chemistry. 56:1211-1216
One-pot three-component reactions of 2,6-diaminopyrimidin-4-(3H)-one with aromatic aldehydes and 1- or 2-naphthol afforded benzo[7,8]chromeno[2,3-d]pyrimidine and benzo[5,6]chromeno[2,3-d]pyrimidine derivatives, respectively. In both cases, the heter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fc39e9b3bd68aba35f0a21e3a3bfbc1
https://doi.org/10.1134/s1070428020070143
https://doi.org/10.1134/s1070428020070143
Autor:
I. S. Danielyan, T. R. Hovsepyan, A. A. Harutyunyan, S. V. Dilanyan, L. E. Nersesyan, N. S. Minasyan, A. S. Agaronyan
Publikováno v:
Russian Journal of General Chemistry. 90:787-793
Bis-1,2,4-triazoles with aryl and alkyl linkers were synthesized. In order to increase their hydrophilicity and potential biological activity, pharmacophore electron-deficient groups (carboxylic, carboxamide, nitrile) were introduced into the molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::328f49ada4d4dcdc0b9b5a9e3bd9be5f
https://doi.org/10.1134/s1070363220050047
https://doi.org/10.1134/s1070363220050047
Autor:
A. S. Agaronyan, M. R. Hakobyan, N. S. Minasyan, R. E. Muradyan, L. E. Nersesyan, T. R. Hovsepyan, I. S. Danielyan
Publikováno v:
Russian Journal of General Chemistry. 89:673-679
Continuing the search for biologically active compounds among functionally substituted azoles, new 1,2,4-triazole-3-thiols and 1,3,4-thiadiazoles derivatives bearing pharmacologically active carboxamide, hydroxyl or carboxyalkyl moieties, as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3f7e415df974debb8aa8b375d9c104
https://doi.org/10.1134/s1070363219040066
https://doi.org/10.1134/s1070363219040066
Publikováno v:
Russian Journal of General Chemistry. 88:1114-1119
A series of new pyrimido[4,5-b]quinoline derivatives was synthesized by three-component cyclocondensation of 2-R1-6-aminopyrimidine-4-ones, 5,5-dimethylcyclohexane-1,3-dione (dimedone), and aromatic or heterocyclic aldehydes in a water medium in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb3b76f3cb5e511ec1edc9c8e9866a3d
https://doi.org/10.1134/s1070363218060117
https://doi.org/10.1134/s1070363218060117
Autor:
G. A. Panosyan, R. G. Melik-Ohanjanyan, T. R. Hovsepyan, L. E. Nersesyan, S. G. Israelyan, G. S. Karakhanyan
Publikováno v:
Russian Journal of Organic Chemistry. 54:107-111
One-step three-component cyclocondensation of 2,6-disubstituted pyrimidin-4(3H)-ones with 1,3-dicarbonyl compounds and some aromatic and heterocyclic aldehydes on heating or under microwave irradiation afforded new functionally substituted 5,8-dihydr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbbf62257d958bbf00cf44fa687809e5
https://doi.org/10.1134/s1070428018010104
https://doi.org/10.1134/s1070428018010104
Autor:
N. S. Minasyan, M. R. Hakobyan, A. S. Agaronyan, R. V. Paronikyan, I. S. Danielyan, L. E. Nersesyan, T. R. Hovsepyan
Publikováno v:
Russian Journal of General Chemistry. 87:973-978
Aminomethylation and cyanoethylation reactions of 5-(4-alkoxybenzyl)-4-methyl(phenyl, allyl)-4H-1,2,4-triazole-3-thiols have been investigated. According to NMR spectroscopy data, the reactions occur at the nitrogen atom Ν2. The effect of the synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5097ffab93a9198a7917c1a8cb6ba6a0
https://doi.org/10.1134/s1070363217050140
https://doi.org/10.1134/s1070363217050140
Publikováno v:
Russian Journal of General Chemistry. 86:1845-1849
2-Substituted 1,3,4-thiadiazole-5-thiol has been synthesized basing on hydrazide of 3-methoxy-phenoxyacetic acid. Methods of SH-alkylation, aminomethylation, and cyanoethylation of the product have been elaborated. Reactions of the starting hydrazide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0af03fce5fd978517072fc17e2fdd95
https://doi.org/10.1134/s1070363216080119
https://doi.org/10.1134/s1070363216080119
Autor:
L. E. Nersesyan, R. V. Paronikyan, T. R. Hovsepyan, I. S. Danielyan, R. G. Melik-Ogandzhanyan, A. S. Agaronyan, F. G. Arsenyan
Publikováno v:
Pharmaceutical Chemistry Journal. 49:231-236
A series of new 3,4,5-substituted 1,2,4-triazoles were synthesized. Their SH-alkylation by various alkylating compounds and aminomethylation leading to the formation of Mannich bases were studied. The influence of the synthesized compounds on the lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88578cd146741ed0eb43bc0a845f6cd
https://doi.org/10.1007/s11094-015-1261-5
https://doi.org/10.1007/s11094-015-1261-5
Autor:
A. G. Ayvazyan, Rafael Tamazyan, M. S. Ghukasyan, R. G. Melik-Ohanjanyan, T. R. Hovsepyan, S. G. Israelyan, G. S. Karakhanyan, Henry A. Panosyan
Publikováno v:
Russian Journal of Organic Chemistry. 51:361-367
New acyclic pyrimidine nucleosides, analogs of the antiviral drug acyclovir, were synthesized starting from 6-chloropyrimidine-2,4(1H,3H)-dione. The addition of side carbohydrate chain to the N1 or N3 atoms of the heterocyclic base with formation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3267543d45564ae4c8cc85e91bce374a
https://doi.org/10.1134/s1070428015030124
https://doi.org/10.1134/s1070428015030124