Zobrazeno 1 - 3
of 3
pro vyhledávání: '"T. P. Upchurch"'
Autor:
J R Lake, S C Johnson, William E. Schweinle, M. Shenoi, T. P. Upchurch, C D Cadle, David H. Malin
Publikováno v:
Psychopharmacology. 140:371-377
Nitric oxide synthesis contributes to opiate tolerance and dependence. Nicotine dependence and abstinence syndrome in the rat appear to involve opiate mechanisms. Therefore, it was postulated that nitric oxide synthase (NOS) activity might be essenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926d542aaabbb5d2509776484fa8de66
https://doi.org/10.1007/s002130050778
https://doi.org/10.1007/s002130050778
Autor:
J. R. Lake, M. Shenoi, B. A. Lawless, J. W. Kirk, C. K. Schopen, E. E. Sailer, T. P. Upchurch, David H. Malin, N. Rajan
Publikováno v:
Pharmacology Biochemistry and Behavior. 58:695-699
A rodent model of nicotine dependence has been developed based on continuous subcutaneous (SC) infusion of nicotine tartrate. Nicotine abstinence syndrome was precipitated by SC injection of the nicotinic antagonist mecamylamine, which freely crosses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42dd26cf4474e18bc0e519374490e16
https://doi.org/10.1016/s0091-3057(97)90006-x
https://doi.org/10.1016/s0091-3057(97)90006-x
Publikováno v:
Pharmacology, biochemistry, and behavior. 60(3)
Rats infused subcutaneously with 9 mg/kg/day nicotine tartrate for 7 days exhibit behavioral abstinence signs following either termination of nicotine infusion or injection of the noncompetitive nicotinic antagonists mecamylamine (s.c.) or hexamethon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fd749957485ba76bcd3becdc55a0fd7
https://pubmed.ncbi.nlm.nih.gov/9678643
https://pubmed.ncbi.nlm.nih.gov/9678643