Zobrazeno 1 - 10
of 24
pro vyhledávání: '"T. P. Ugarova"'
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 6, Pp 94-105 (2013)
Current knowledge of the mechanisms of blood coagulation does not provide an answer to one pivotal question: why is, in contrast to a pathological thrombus, the growth of normal hemostatic clot after blood vessel injury suddenly terminated? In the pr
Externí odkaz:
https://doaj.org/article/3396b2a491484ee9a502bb6654558f21
Autor:
V.N. Kalikhevich, T. P. Ugarova, Z.A. Ardemasova, N.I. Lukinova, Leonid Medved, S.V. Litvinovich
Publikováno v:
FEBS Letters. 320:239-242
Dansyl-labeled tetrapeptide Gly-His-Arg-Pro which mimics the central fibrin polymerization site was used to investigate its binding to a number of fibrinogen fragments containing different numbers of domains. The tetrapeptide was found to bind to fra
Autor:
T P Ugarova, A Z Budzynski
Publikováno v:
Journal of Biological Chemistry. 267:13687-13693
Plasmic degradation products of human fibrin, fragments DD, D, and E, bind to fibrin. It has been inferred from this observation that the binding occurs by attraction of complementary sites located in the NH2- and COOH-terminal domains of the fibrin
Publikováno v:
Blood. 98(8)
The interaction of human plasma fibrinogen with leukocyte integrins alpha(M)beta(2) (CD11b/CD18, Mac-1) and alpha(X)beta(2) (CD11c/CD18, p150,95) is an important component of the inflammatory response. Previously, it was demonstrated that binding of
Publikováno v:
The Journal of biological chemistry. 276(17)
The leukocyte integrin alpha(M)beta(2) (Mac-1, CD11b/CD18) is a cell surface adhesion receptor for fibrinogen. The interaction between fibrinogen and alpha(M)beta(2) mediates a range of adhesive reactions during the immune-inflammatory response. The
Publikováno v:
Ukrains'kyi biokhimichnyi zhurnal (1999 ). 71(2)
Series of methyl esters of stereoisomeric dipeptides of the sequences Tyr-Arg and Arg-Tyr has been synthesized by classic methods of the peptide chemistry. The study of their reactivity towards thrombin and trypsin has shown that the kinetic paramete
Publikováno v:
The Journal of biological chemistry. 273(35)
The interaction of leukocyte integrin alphaMbeta2 (CD11b/CD18, Mac-1) with fibrinogen has been implicated in the inflammatory response by contributing to leukocyte adhesion to the endothelium and subsequent transmigration. Previously, it has been dem
Publikováno v:
Ukrainskii biokhimicheskii zhurnal (1. 68(4)
Publikováno v:
Biokhimiia (Moscow, Russia). 61(6)
Ecamulin, a novel prothrombin activating enzyme, has been isolated and purified 63-fold with a 57% yield from the venom of the Middle-Asian sand viper Echis multisquamatus using three-step ion-exchange chromatography. The enzyme was shown to activate
Publikováno v:
Klinicheskaia laboratornaia diagnostika. (6)
A new method is suggested for blood plasma fibrinogen measurements, making use of ancystron-N thrombin-like enzyme, isolated from common viper venom. Comparative studies have demonstrated the possibility of using the new test for plasma fibrinogen de