Zobrazeno 1 - 10
of 27
pro vyhledávání: '"T. P. Smolina"'
Autor:
T. A. Kuznetsova, T. P. Smolina, E. V. Persiyanova, L. A. Ivanushko, A. S. Silchenko, S. P. Ermakova, N. N. Besednova
Publikováno v:
Биопрепараты: Профилактика, диагностика, лечение, Vol 22, Iss 3, Pp 308-317 (2022)
The use of sulfated polysaccharides (fucoidans) as active pharmaceutical ingredients or adjuvants poses the challenge of obtaining structurally characterised and homogeneous samples or their oligomeric fractions maintaining high biological activity.
Externí odkaz:
https://doaj.org/article/719ed4b54cac454591a5e6e2832fb5c9
Autor:
T. A. Kuznetsova, E. V. Persiyanova, L. A. Ivanushko, T. P. Smolina, A. K. Gazha, M. S. Kokulin, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 66, Iss 5-6, Pp 17-22 (2021)
Aim. To assess the mechanisms of immunoadjuvant activity of marine bacteria exopolysaccharides (PS) in normal and immunosuppressive conditions in vivo. Material and methods. Experimental studies were carried out on male ВALB/c mice, immunized with c
Externí odkaz:
https://doaj.org/article/3dde3914c93146279a4e0a7269abfd15
Autor:
T. S. Zaporozhets, S. P. Kryzhanovsky, E. V. Persianova, T. A. Kuznetsova, T. P. Smolina, A. K. Gazha, N. M. Shevchenko, S. P. Ermakova, T. N. Zvyagintseva, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 65, Iss 3-4, Pp 23-28 (2020)
The article establishes the particularities of immune system dysfunction in the elderly during formation of a specific immune response to vaccination with a seasonal influenza vaccine depending on the level of seroconversion. The corrective effect of
Externí odkaz:
https://doaj.org/article/e6612da65e1348529aa10315b6775730
Autor:
T. A. Kuznetsova, N. N. Besednova, T. S. Zaporozhets, T. P. Smolina, A. K. Gazha, L. A. Ivanushko
Publikováno v:
Антибиотики и Химиотерапия, Vol 58, Iss 11-12, Pp 8-12 (2020)
The immunomodulatory activity of peptide drugs: i.e. tinrostim (dosage form) prepared of squid optical ganglia and pharmacopoeia thymalin was studied. Tinrostim showed a stimulating effect on the humoral and cellular immune responses when administere
Externí odkaz:
https://doaj.org/article/024555c232f84bc794a6163271a3eb84
Autor:
N. N. Besednova, T. P. Smolina, B. G. Andryukov, T. A. Kuznetsova, V. V. Mikhailov, T. N. Zvyagintseva
Publikováno v:
Антибиотики и Химиотерапия, Vol 63, Iss 7-8, Pp 67-78 (2020)
The review presents the main directions of biomedical research on exopolysaccharides (EPS) obtained from various species of marine bacteria. EPS are high molecular weight polymers consisting of sugar residues; they are characterized by a large variet
Externí odkaz:
https://doaj.org/article/cad3053e2d844f2fac247e4c70effb71
Publikováno v:
Антибиотики и Химиотерапия, Vol 62, Iss 7-8, Pp 3-7 (2020)
It has been shown that using the cytometric method lipopolysaccharide (LPS) and extracellular polysaccharide (EPS) isolated from marine bacteria Pseudoalteromonas nigrifaciens increase the relative amount of monocytes synthesizing IL-12. LPS and EPS
Externí odkaz:
https://doaj.org/article/97beee21c1c44cf9b001982e88ab7e82
Publikováno v:
Антибиотики и Химиотерапия, Vol 64, Iss 11-12, Pp 16-24 (2020)
The aim of this study was to examine the immunocorrective and antiviral activity of extracellular polysaccharide (EPS) from the marine bacteria Pseudoalteromonas nigrifaciens against tick-borne encephalitis virus (TBEV). Materials and Methods. The cy
Externí odkaz:
https://doaj.org/article/b9e565b63852421aa48fe39dc135f40d
Autor:
T. A. Kuznetsova, T. P. Smolina, N. N. Besednova, A. S. Silchenko, T. I. Imbs, S. P. Ermakova
Publikováno v:
Антибиотики и Химиотерапия, Vol 61, Iss 7-8, Pp 10-14 (2020)
The effect of sulfated polysaccharides (PS) from brown alga Fucus evanescens and their enzymatic transformation and low molecular weight product on the functional activity of the innate immunity cells, i.e. polymorphonuclear leukocytes of human perip
Externí odkaz:
https://doaj.org/article/aa04bfe7845549229706a7b40b2ada08
Autor:
T. P. Smolina, T. A. Kuznetsova, L. A. Ivanushko, A. K. Gazha, A. S. Silchenko, N. N. Besednova
Publikováno v:
Антибиотики и Химиотерапия, Vol 64, Iss 9-10, Pp 3-7 (2020)
The article studies the effect of sulfated polysaccharide extracted from brown algae Fucus evanescens(fucoidan) and the product of its enzymatic transformation on human NK and NKT cells. Significant phenotypic changes in NK and NKT cells were recorde
Externí odkaz:
https://doaj.org/article/3789fe4a531c4cb4a8747eef84ebe1e2
Publikováno v:
Антибиотики и Химиотерапия, Vol 60, Iss 5-6 (2020)
By flow cytometry it was demonstrated that lipopolysaccharide and exopolysaccharide of marine proteobacteria Pseudoalteromonas nigrifaciens alter the expression of adhesion molecules on human neutrophils and monocytes, reducing the expression level o
Externí odkaz:
https://doaj.org/article/4cef7dcefa66425ca36403f51e0ee49c