Výsledky vyhledávání - "T. P. Loughran"

Major histocompatility complex haplotypic associations in Felty's syndrome and large granular lymphocyte syndrome are secondary to allelic association with HLA-DRB1 *0401

Autor: Robert Vaughan, Gabriel S. Panayi, Gillian Coakley, M. Iqbal, E. Kondeatis, David J. Brooks, T. P. Loughran, Jerry S. Lanchbury

Publikováno v: Scopus-Elsevier

Objective To investigate the role of HLA class I in susceptibility to Felty's syndrome (FS) and large granular lymphocyte (LGL) syndrome. Methods Fifty caucasoid FS patients, and 55 patients with LGL syndrome, of whom 26 had arthritis and 29 did not,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102cb879d31bafe3988fe05ef427d3ae
https://doi.org/10.1093/rheumatology/39.4.393

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Genetic polymorphism of IL-12 p40 gene in immune-mediated disease

Autor: Edwina McGlinn, Kyriaki A. Boki, William E R Ollier, Sheila A. Fisher, Margaret A. Hall, E Kaklamani, Gabriel S. Panayi, T P Loughran, Gillian Coakley, Haralampos M. Moutsopoulos, Jerry S. Lanchbury, Derek Middleton

Publikováno v: Genes & Immunity. 1:219-224

Understanding of the genetic basis of autoimmune diseases is currently incomplete. Cytokine gene polymorphisms warrant consideration as factors explaining variation in the human immune and inflammatory responses and as candidate susceptibility genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a154133e9072dcebecab79ecbcac09a3
https://doi.org/10.1038/sj.gene.6363661

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A Fas promoter polymorphism at position −670 in the enhancer region does not confer susceptibility to Felty's and large granular lymphocyte syndromes

Autor: Jerry S. Lanchbury, T. P. Loughran, N. Manolios, Gabriel S. Panayi, Gillian Coakley

Publikováno v: Rheumatology. 38:883-886

Objective. We examined whether there are associations between a polymorphism in the Fas promoter, recently found to be associated with rheumatoid arthritis (RA), and Felty's syndrome or large granular lymphocyte (LGL) leukaemia. Methods. Thirty-five

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0675c9e9d4818361d2f85b5f59cfab
https://doi.org/10.1093/rheumatology/38.9.883

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Extramedullary granulopoiesis mimicking recurrent lymphoma after prolonged administration of human recombinant granulocyte colony-stimulating factor

Autor: T. P. Loughran, K. W. Zamkoff, S. O. Sanderson, N. J. Gonchoroff, C. K. Stein, H. D. Friedman, A. Shrimpton

Publikováno v: Annals of Hematology. 77:79-83

Human recombinant granulocyte colony-stimulating factor (G-CSF) has become a treatment of choice for neutropenia of diverse etiologies. We describe a 71-year-old man who, while receiving G-CSF for graft failure after peripheral blood stem cell transp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c70006e93d08544eb39709d3f50fc74
https://doi.org/10.1007/s002770050417

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Clinical spectrum of gammadelta+ T cell LGL leukemia: analysis of 20 cases

Autor: A S, Bourgault-Rouxel, T P, Loughran, R, Zambello, P K, Epling-Burnette, G, Semenzato, J, Donadieu, L, Amiot, T, Fest, T, Lamy

Publikováno v: Leukemia Research
Leukemia Research, Elsevier, 2008, 32 (1), pp.45-8. ⟨10.1016/j.leukres.2007.04.011⟩
Leukemia Research, 2008, 32 (1), pp.45-8. ⟨10.1016/j.leukres.2007.04.011⟩

International audience; We report on the clinico-biological characteristics of 20 cases of gammadelta T cell large granular lymphocyte (LGL) leukemia. All the data were compared to that of 196 cases with alphabeta T cell subtype, which represents the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::31e05d5d5e164ed45448f0a09e1c3c21
https://hal.archives-ouvertes.fr/hal-00690765

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A comparison of the Brooker-Wills and Russell-Taylor nails for treatment of patients who have fractures of the femoral shaft

Autor: John A. Cardea, R S Adelaar, T P Loughran, J F Blumberg, R W Hussey, M E Deblois, William C. Foster, K D Blumberg

Publikováno v: The Journal of Bone & Joint Surgery. 72:1019-1024

Seventy-three fractures of the femoral shaft (seventy patients) were randomized to treatment with interlocked nailing with either the Brooker-Wills femoral nail (thirty-nine fractures) or the Russell-Taylor femoral nail (thirty-four fractures). Sixty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4103045138fc9872550ffa0459916524
https://doi.org/10.2106/00004623-199072070-00010

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Lack of BLV and PTLV DNA sequences in the majority of patients with large granular lymphocyte leukaemia

Autor: R N, Perzova, T P, Loughran, S, Dube, J, Ferrer, E, Esteban, B J, Poiesz

Publikováno v: British journal of haematology. 109(1)

The primate T-cell lymphoma/leukaemia viruses (PTLV) and bovine leukaemia virus (BLV) comprise a unique genus of retroviruses, infection with which induces seroreactivity in the host against conserved epitopes in their p24 gag and gp21 env cognate pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54e3295b4a3a6e001e420a87b9c24d05
https://pubmed.ncbi.nlm.nih.gov/10848783

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Chronic neutropenia mediated by fas ligand

Autor: J H, Liu, S, Wei, T, Lamy, P K, Epling-Burnette, G, Starkebaum, J Y, Djeu, T P, Loughran

Publikováno v: Blood. 95(10)

Chronic neutropenia, often associated with rheumatoid arthritis, is a characteristic finding in large granular lymphocyte (LGL) leukemia. The mechanism of neutropenia is not known. Normal neutrophil survival is regulated by the Fas-Fas ligand apoptot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::58dfbec8815e14d06b74674656f1bb83
https://pubmed.ncbi.nlm.nih.gov/10807792

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