Zobrazeno 1 - 10 of 16 pro vyhledávání: '"T. P. Huecksteadt"'
1
RAGE is a Critical Mediator of Pulmonary Oxidative Stress, Alveolar Macrophage Activation and Emphysema in Response to Cigarette Smoke
Autor: Tanna Wuren, Mark Hazel, Karl Sanders, Yuxia Zhang, Don A. Delker, John R. Hoidal, Yuntian Chen, T. P. Huecksteadt, Emily Beck
Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific Reports
The receptor for advanced glycation end products (RAGE), a cell membrane receptor, recognizes ligands produced by cigarette smoke (CS) and has been implicated in the pathogenesis of COPD. We demonstrate that deletion or pharmacologic inhibition of RA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6909c3a07c3ed79a475a4f56f18d0c83
http://link.springer.com/article/10.1038/s41598-018-36163-z
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2
The receptor for advanced glycation endproducts (RAGE) decreases survival of tumor-bearing mice by enhancing the generation of lung metastasis-associated myeloid-derived suppressor cells
Autor: Emily Beck, Tanna Wuren, John R. Hoidal, Kristi J. Warren, Karl Sanders, Suzanne Ostrand-Rosenberg, T. P. Huecksteadt
Publikováno v: Cellular immunology. 365
Metastatic cancer has a poor prognosis. Novel pharmacologic targets need to be identified. The receptor for advanced glycation endproducts (RAGE) is a pattern recognition receptor constitutively expressed in the lungs. Absence of overt disease in RAG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f959f4a94a1ee7f2767770af2d1bd06
https://pubmed.ncbi.nlm.nih.gov/34038758
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3
RAGE: developmental expression and positive feedback regulation by Egr-1 during cigarette smoke exposure in pulmonary epithelial cells
Autor: Manuel G. Cosio, John R. Hoidal, Anne Sturrock, T. P. Huecksteadt, Stephen D. Kasteler, Paul R. Reynolds
Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology. 294:L1094-L1101
The receptor for advanced glycation end-products (RAGE) is a member of the immunoglobin superfamily of multiligand receptors. Following ligand binding, mechanisms associated with host defense, tissue remodeling, and inflammation are activated. RAGE i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2e54d16c910af91ed41dbf1de49948
https://doi.org/10.1152/ajplung.00318.2007
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5
Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation
Autor: K D Pfeffer, T P Huecksteadt, J R Hoidal
Publikováno v: The Journal of Immunology. 153:1789-1797
Reactive oxygen species have been implicated in the tissue injury and loss of epithelial barrier function associated with a number of clinical disorders in which disregulated inflammation seems to be a dominant event, such as endotoxemia and viral sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b472a891a877d1d14ea41ff1e7fd8e43
https://doi.org/10.4049/jimmunol.153.4.1789
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7
Regulation of xanthine dehydrogenase and xanthine oxidase activity by hypoxia
Autor: T. P. Huecksteadt, P. C. Panus, W. B. Poss, John R. Hoidal, B. A. Freeman
Publikováno v: The American journal of physiology. 270(6 Pt 1)
The present study determined the effect of hypoxia on xanthine dehydrogenase (XDH) and xanthine oxidase (XO) activity and gene and protein expression in cultured bovine aortic endothelial cells (BAEC). BAEC were exposed to hypoxia (3% O2) or anoxia (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d9dd4e9ae4af5a914ed267084e6a3e
https://pubmed.ncbi.nlm.nih.gov/8764218
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8
Xanthine dehydrogenase and xanthine oxidase activity and gene expression in renal epithelial cells. Cytokine and steroid regulation
Autor: K D, Pfeffer, T P, Huecksteadt, J R, Hoidal
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 153(4)
Reactive oxygen species have been implicated in the tissue injury and loss of epithelial barrier function associated with a number of clinical disorders in which disregulated inflammation seems to be a dominant event, such as endotoxemia and viral sy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8a7c23c08f0fdaa5ad96cbd857848f22
https://pubmed.ncbi.nlm.nih.gov/8046245
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9
Molecular cloning, tissue expression of human xanthine dehydrogenase
Autor: Ping Xu, T. P. Huecksteadt, R. Harrison, John R. Hoidal
Publikováno v: Biochemical and biophysical research communications. 199(2)
Xanthine dehydrogenase (XDH, EC 1.1.1.204) is a molybdenum iron-sulphur flavin hydroxylase which oxidizes a variety of purines, pterins and other heterogenic nitrogen compounds, serving as a rate-limiting enzyme in nucleic acid degradation. In this w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9899ffc7cbf1357f080ad2573935f90
https://pubmed.ncbi.nlm.nih.gov/7575623
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