Quality of Anticoagulation Control in Preventing Adverse Events in Patients With Heart Failure in Sinus Rhythm

Autor: S. Shaw, Conrado J. Estol, Biykem Bozkurt, B. Donelly, R. Berkowitz, L. Berente, M. Jurczok, J. Simon, Sami Khella, A. Travis, M. Schoenauer, Ronald S. Freudenberger, Anikó Ilona Nagy, G. Marcinek, M. Hajkova, T. Siebert, R. Breedveld, W. Baker, P. Avellana, S. Kozhukhov, M. Diek, J. Jaros, R. Vicari, S. Timar, C. Schanz, J. Povolny, M. van Zagten, Shelley Zieroth, G. Rex, M. Apelian, M. Dzaiy, K. Hayward, A. Warner, L. Baliko, Piotr Ponikowski, S. Mathus, Arthur J. Labovitz, C. DeMers, E. Péterfai, Mariana Bolos, B. Stephens, F. Tito, Denise L. Janosik, N. Molakala, J. Dizes, R. van der Loo, A. van Bujisen-Nutters, K. Wolf, S. Nawaz, A. Boguschewski, D. Ferguson, A. McPhail, M. Rohwedder, M. Malkowski, R. Prodhan, P. Miekus, R. Pellegrino, M. Rossi, Michelle Bierig, E. Wirkowski, Zbigniew Gaciong, F. Guerlloy, D. Chupka, O. Kovtun, M. Padour, D. Horak, Elly M.C.J. Wajon, J. Carda, P. Gregor, M. Tilem, P. Kosolcharoen, R. Wensel, V. Garman, N. Torok, B. Benczur, E. Peña, G. Moe, B.M. Massie, S. Slomiak, C. Benesch, V. Orlyk, K. Greenan, M. Ogorek, I. Jedlinski, Shun Kohsaka, R. Haynes, Z. Lorenc, M. Kuchar, R. Pauer, T. Dugan, A. Juszczak, T. Schrader, A. Henriquez, K. Toth, M. Varga, J. Herman, M. Lee, M. Dunaj, L. Krizova, M. Bonora, P. Loviska, D. Aubin, M. Kokles, J. D. Easton, J. Meschia, A. Bruno, Steven Goldman, S. Voigt, D. Malchik, A. Tierney, Demetrios J. Sahlas, N. Elzebroek, Richard J. Hobbs, M. Charlet, B. Hattler, L. Regos, Dennis Wolf, A. Peljto, C. Lindsey, R. Winkler, J. Arredondo, B. Oze, C. Schuler, D. Bruck, E. Jones, G. Torre, S. Nabhan, G. Mallis, Jindřich Špinar, W. Graettinger, A. Ruiz, N. Holwerda, R. Katz, J. Gonzalez, Christine Gerula, P. Jansky, H. V. Anderson, B. Krizova, Andreas König, M. Moussavian, M. Konarzewski, G. Jakab, M. Liston, Elizabeth O. Ofili, L. Nikolaidis, Susan E. Ammon, Rebekka K. Schneider, M. Krauze-Wielicka, M. Zimmermann, J. Lynch, J. Minuk, F. Sokn, Douglas L. Mann, R. Sawyer, J. Partridge, D. Leifer, M. Bohdanowicz-Zazula, D. Barratt, C. Dewar, S. Kolomiets, T. Noonan, D. Beran, M. Jeserich, J. Wong, R. Bessoudo, M. Lichtenberger, E. Bednarova, R. Serafin, M. Scullin, I. Kosa, M. Hranai, E. Duverger, L. Joseph, A. M. Sindilar, I. Edes, E. Yakimenko, J. Hobbs-Williams, F. Novoa, A. Szczepanska, R. Wachter, P. A. de Milliano, L. Golan, Gregory W. Albers, K. Ammerman, Alexandra R. Sanford, W. Burgin, A. Richmond, A. Kleinrok, B. Dandapani, Laurie Gutmann, M. Houra, Udho Thadani, P. Schygiel, A. van Hessen, Christian Weber, S. Mehešová, P. Stein-Beal, E. Flanagan, R. Khadouri, P. Chang, Thomas P. Cappola, L. Konczarek, B. Mangariello, L. Atkins, C. McKay, J. Svoboda, O. Lesniak, L. Westbrook, S. J. Kim, C. Moy, M. Kuch, M. Nemec, M. Krobot, B. Kozlowski, M. Applegate, M. Kiorwantsi, J. Thierer, K. Craig, A. Slim, Y. Besaga, R. Kuba, P. Fulop, K. Crotto, R. Porcile, E. Falgout, E. Olgren, K. Kuc, Marcus F. Stoddard, W. Almeida, L. Pas, L. Williams, I. Sorokina, J. Rodl, S. Sparr, A. Coppes, E. Ronner, A. Jurczyk, S. Gass, John R. Teerlink, P. Kucera, H. J. Barnett, B. McGinnis, L. Wilson, Y. Tutov, R. MacFadyen, Gregory Y.H. Lip, V. Sorrell, T. Ochalek, J. Turner, M. Modzelewski, Matthew Wilson, A. Ogorodnichuk, C. Anderson, P. de Kort, B. Palossy, Alan B. Miller, T. Giles, H. Brown, Andrew H. Baker, P. Czaja, Roman Szełemej, J. Hanna, P. Gilbert, A. Metcalf, R. Piotrowski, D. Yip, B. Coull, P. Gitelman, Burkert Pieske, C. Rapallo, M. Morgil, M. Resch, A. Zachar, Jan Biegus, W. Watson, J. A. Hinchey, E. Polland, L. Caufield, D. Kopcik, E. Pechackova, M. Calderon, Stefan D. Anker, V. Virkud, R. Rothbart, L. Rudenko, W. Wicha, B. Jacques, Susan Graham, J. Donaldson, O. Girina, L. Guillory, S. Khoury, I. Padourova, Haissam Haddad, L. Kowalczyk, J. A. Swain, G. Prokop-Lewicka, R. Mattessich, K. Remmel, S. Tikhonova, S. Klochkov, J. Leppo, K. C. Johnston, D. Gohs, Peter K. Smith, Eric E. Smith, V. Hart, J. Vanyi, L. Voronkov, G. Allam, M. Klapholz, T. Varadyova, S. Daugherty, L. Witkin, K. Panizzon, B. Drachman, S. Locke, Ann‐Katrin Mojica Munoz, J. Love, T. Winder, P. Bailey, T. Huynh, G. A. Verheul, Tomasz J. Pasierski, J. Borbola, R. Liu, A. Elizalde, C. Walker, R. Kelley, Robert Côté, P. Frey, J. McGee, Peter E. Carson, T. Bator, Donald L. Patrick, K. Karsay, J. Plomp, O. Novikova, J. Vuijsters, Jay P. Mohr, A. Parkhomenko, A. Ducharme, C. Alteri, S. Borden, Siqin Ye, W. Felton, K. Peterson, M. Satori, N. Polenova, D. Karia, G. Turhan, R. Nagy, K. Amosova, J. Michalska, R. Libman, E. Frey, O. Najmanova, R. Yufe, O. Montaña, S. Bailey, M. Bodi, A. Ellis, J. Tarchalski, L. Sitwell, M. Del Valle, John P. Boehmer, J. Marler, P. Romia, K. Tea, E. Hartmann, R. Lebedova, V. Yurlov, O. Karpenko, Malcolm Arnold, P. Berkowski, J. Johnson, P. Ramappa, R. Ferkl, Dirk J. Lok, N. Bayer, S. Bezucha, A. Mercando, H. Tworek, R. Longaker, P. Jinkins, J. Kirmani, L. Svoboda, David Spence, Min Qian, John L.P. Thompson, N. Brodi, Y. Prokopovych, Sedat Sen, M. Nanna, S. T. Palmeri, M. Michalova, L. Giron, K. Wolkowska, D. Borts, K. Hamroui, G. Linssen, L. Arcement, A. McNulty, C. Jakobs, F. Bleyer, W. Lo, J. Bisognano, J. Kosits, Steven R. Levine, G. Berry, P. Heidrich, G. Kiss, G. Tullio, J. Yasen, G. Ortiz, B. O'Hare, P. Jackson, T. Rennie, Z. Davidovits, G. v Buchem-Damming, H. Dvorakova, W. Hermans, Zbigniew Kalarus, H. Morgil, C. Harris, M. Vissiennon, Shunichi Homma, André P. Gabriel, J. Aiub, I. Katzan, C. Zaidman, S. Sassone, A. Duszanska, J. Litvinova, P. Kralicek, M. Natour, E. Nagy, E. Nishime, M. J. Bos, S. Nowakowska, J. Beebe, B. Watson, N. Jacek, Ralph L. Sacco, A. Cwynar, S. Pezzella, B. George, B. Hott, T. Vegh, V. Mejia, E. Janzen, M. Eliasziw, Heribert Schunkert, L. Swydan, J. Gora, D. Drazek, C. Landau, L. Roffidal, L. Casazza, Andrew M Penn, Richard L. Hughes, V. Schumann, R. Santi, I. Sakharchuk, A. Adler, D. Taylor, C. F. Peerenboom-Fey, M. Dluzniewski, L. Cape, Attila Kovacs, E. Ziekenhuis, A. Bujdoso, L. Fischer, Richard Buchsbaum, Petr Arenberger, L. Pollak, J. Vosmerova, B. Donley, Patrick M. Pullicino, B. Darrow, A. Minagar, N. Jarmukli, J. Dissin, M. Daniels, L. Csuros, G. J. del Zoppo, E. Anthony, B. Metzkier-Wyrwa, A. Ronaszeki, I. Malek, R. Arbing, Gilberto Levy, D. Mauceri, Carlos J. Rodriguez, V. Kovalenko, J. Smith, O. Yaremenko, R. de Graaf Gasthuis, C. Donato, L. Spinarova, Martin M. Brown, F. Padour, O. Lovasz, Marco R. Di Tullio, K. Balaban, S. Donovan, S. Genth-Zotz, M. Maruskova, I. Varga, T. Drasnar, V. Berchou, R. Davies, Robert G. Hart, M. Lebedynska, G. Hageman, D. Disantis, W. Schneider, M. Frankel, A. Hajnalne, S. Baumann, P. Karpati, L. C. Pettigrew, Johnston Grier, A. Ellenberg, Bruce Levin, Stephanie Hope Dunlap

Publikováno v: Circulation: Heart Failure. 8:504-509

Background— The aim of this study is to examine the relationship between time in the therapeutic range (TTR) and clinical outcomes in heart failure patients in sinus rhythm treated with warfarin. Methods and Results— We used data from the Warfari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31a0db83993934e5f54c8f49c040871b
https://doi.org/10.1161/circheartfailure.114.001725

Small-Molecule Inhibitors of 25-Hydroxyvitamin D-24-Hydroxylase (CYP24A1): Synthesis and Biological Evaluation

Autor: Andrea Brancale, Claire Simons, Chris Pepper, Salvatore Ferla, Justin T. Ochalek, Jinge Zhu, Ahmed S. Aboraia, Hector F. DeLuca

Publikováno v: Journal of Medicinal Chemistry. 57:7702-7715

The synthesis of imidazole styrylbenzamide, tert-butyl styrylimidazole, and tert-butyl styrylsulfonate derivatives is described. Evaluation of binding affinity and inhibitory activity against CYP24A1 identified the imidazole styrylbenzamides as poten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6126ade9051c95c2959dd02a8d274fbe
https://doi.org/10.1021/jm5009314

CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo

Autor: Glenville Jones, Martin Kaufmann, Hector F. DeLuca, Justin T. Ochalek, Jinge G. Zhu

Bioactivation of vitamin D consists of two sequential hydroxylation steps to produce 1α,25-dihydroxyvitamin D3. It is clear that the second or 1α-hydroxylation step is carried out by a single enzyme, 25-hydroxyvitamin D 1α-hydroxylase CYP27B1. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e6896be2103752e53731d9cc40874e
https://europepmc.org/articles/PMC3785760/

Cytogenetics of Synovial Sarcoma: Presentation of Ten New Cases and Review of the Literature

Autor: H. Nosek, J. Rys, T. Ochalek, Andrzej Kopacz, Niezabitowski A, N. Mandant, Janusz Limon, Anders Rydholm, Felix Mitelman, K. Mrózek, A. Verhest, Małgorzata Babińska, Helena Willén, Bogusław Nedoszytko, Sverre Heim

Publikováno v: Genes, Chromosomes and Cancer. 3:338-345

Cytogenetic study of five biphasic and five monophasic synovial sarcomas revealed the specific abnormality t(X; 18) (p 11;q 11 ) in eight cases and t(X;15;18) (p11;q15;q111) and t(X;7) (q11–12;q32) in one case each. Additional, secondary aberration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c75c5c9084c5b2b7aafe548c2e6189
https://doi.org/10.1002/gcc.2870030504

In vitro generation of therapeutic noncytolytic T-cells by soluble polyoma TAA and Il-2

Autor: T, Ochalek, S, von Kleist

Publikováno v: Anticancer research. 13(4)

Culture requirements for the optimal generation of polyoma-specific therapeutic lymphocytes by in vitro sensitization with soluble polyoma TAA were studied in bulk cultures of splenocytes from polyoma bearing mice. The acquisition of antipolyoma reac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ca236ea7924758f5e6c136d9446fdc53
https://pubmed.ncbi.nlm.nih.gov/8394674