Zobrazeno 1 - 10
of 188
pro vyhledávání: '"T. Nabata"'
Publikováno v:
Alimentary Pharmacology & Therapeutics
SummaryBackground ONO-2952 is a novel and selective inhibitor of translocator protein 18 kDa that reduces stress-induced defecation and visceral hyperalgesia in rat models. Aim To evaluate the efficacy and safety of ONO-2952 in females with irritable
Autor:
G. M. Gauvreau, L.-P. Boulet, J. M. FitzGerald, D. W. Cockcroft, B. E. Davis, R. Leigh, M. Tanaka, J. A. Fourre, T. Nabata, P. M. O'Byrne
Publikováno v:
Allergy. 71:1721-1727
Background The cysteinyl leukotrienes (cysLTs) play a key role in the pathophysiology of asthma. In addition to functioning as potent bronchoconstrictors, cysLTs contribute to airway inflammation through eosinophil and neutrophil chemotaxis, plasma e
Autor:
G M, Gauvreau, L-P, Boulet, J M, FitzGerald, D W, Cockcroft, B E, Davis, R, Leigh, M, Tanaka, J A, Fourre, T, Nabata, P M, O'Byrne
Publikováno v:
Allergy. 71(12)
The cysteinyl leukotrienes (cysLTs) play a key role in the pathophysiology of asthma. In addition to functioning as potent bronchoconstrictors, cysLTs contribute to airway inflammation through eosinophil and neutrophil chemotaxis, plasma exudation, a
Publikováno v:
Alimentary Pharmacology & Therapeutics. 45:1005-1005
Autor:
Hiroshi Ohkuma, Keisuke Fukuo, Akira Nishibe, Toshio Ogihara, Naoko Momose, Shigeto Morimoto, T Nabata, Toshimitsu Suhara, Masumi Shimizu, Takeshi Nakahashi, Hiroyuki Nishimaki, Atsushi Hirotani, Shigeki Hata, Tadaaki Niinobu, Shoroku Sakurai, Shoichi Kitano
Publikováno v:
Atherosclerosis. 133:23-30
Preincubation with interleukin-2 (IL-2), a T cell-derived cytokine, enhanced the increase in intracellular Ca2+ ([Ca2+]i) induced by angiotensin II (AII) in vascular smooth muscle cells (VSMC). IL-2 itself did not affect the basal [Ca2+]i level or th
Autor:
Keisuke Fukuo, T Nabata, Hiromi Rakugi, Jun Tomita, Eio Koh, Takuo Inoue, Shigeto Morimoto, Bingbing Jiang, Toshio Ogihara
Publikováno v:
Europe PubMed Central
The effects of CV-11974, a potent nonpeptide antagonist of the angiotensin II (AII) type-1 receptor (AT1), on cytosolic free calcium concentration ([Ca2+]i), hyperplasia, and hypertrophy of cultured vascular smooth muscle cells (VSMC) from rat aorta
Publikováno v:
Atherosclerosis. 110:111-117
To define the physiological roles of elastase in the vascular wall, we examined whether elastase at low concentrations can modulate the proliferation of vascular smooth muscle cells (VSMC). Elastase itself at low concentrations from 1 to 50 ng/ml inh
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Autor:
Shoichi Kitano, Katsuhiko Sakaguchi, T Nabata, Takuo Inoue, Tsunehito Shiraishi, Shigeto Morimoto, Yoshiyuki Miyashita, Shunji Imanaka, R Morita, Kazuhisa Taniguchi, Eio Koh, Toshio Ogihara, Kazuyuki Itoh, Keisuke Fukuo
Publikováno v:
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics. 28:371-376
We studied the influence of aging on the stimulatory effect of parathyroid hormone (PTH) to (Ca2+ + Mg2+)-ATPase activity of rabbit renal basolateral membrane (BLM). Stimulated by PTH, (Ca2+ + Mg2+)-ATPase activity of BLM from aged rabbits was lower
Autor:
Shigeto Morimoto, Shoichi Kitano, Atsushi Kamitani, Toshio Ogihara, T Nabata, Shoshi Takamoto, Yoshiyuki Miyashita
Publikováno v:
Folia Endocrinologica Japonica. 66:1148-1157
We treated a 29-year-old male patient with pseudohypoparathyroidism type I, who showed a slight increase in serum indirect bilirubin without any signs of liver dysfunction. Serum levels of total, direct and indirect bilirubins were 2.4, 0.7 and 1.7mg