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4-Anilidopiperidine analgesics. 3. 1-Substituted 4-(propananilido)perhydroazepines as ring-expanded analogs

Autor: T N Riley, Z G Finney

Publikováno v: Journal of Medicinal Chemistry. 23:895-899

A study of ring-expanded analogues of the 4-(propananilido)piperidine analgesics has been undertaken in order to evaluate the influence of this structural modification on both analgesic activity and physical-dependence capacity. Thus, a series of 1-s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3370a7756b19c569d4b39ab1be71ca
https://doi.org/10.1021/jm00182a016

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Synthesis and alpha-adrenolytic activity of chiral beta-haloethylamines

Autor: T N, Riley, F W, Crawford

Publikováno v: Journal of pharmaceutical sciences. 65(4)

Several series of N,N-diaralkyl- and N-aryloxyalkyl-N-aralkyl-beta-haloethylamines were synthesized containing centers of chirality in the aralkyl substituent and in the beta-haloethyl moiety to study the stereoselectivity of alpha-adrenolytic activi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5291822d0636dc429e80e953c58b6a76
https://pubmed.ncbi.nlm.nih.gov/5589

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