Zobrazeno 1 - 10
of 14
pro vyhledávání: '"T. N. Lupanova"'
Publikováno v:
Doklady Biochemistry and Biophysics. 506:220-222
Based on previous studies, two antibody-like molecules, monobodies, capable of high-affinity interaction with the SARS-CoV-2 nucleocapsid protein (dissociation constant of tens of nM) were selected. For delivery to target cells, genetically engineere
Autor:
O. A. Zhuravliova, S. L. Lobastov, V. M. Retivov, N. V. Bulushova, V. P. Veiko, T. N. Lupanova, T. A. Voeikova, Tatiana Ismagulova, V. G. Debabov
Publikováno v:
Inorganic Materials: Applied Research. 10:1394-1400
A simple and environmentally safe method for obtaining stable nanoparticles of metal sulfides nanoparticles – NpAg2S, NpCdS and NpZnS was developed using different strains of microorganisms in an aqueous solution of metal salts and sulfur sources a
Publikováno v:
Doklady. Biochemistry and biophysics. 503(1)
Seven amino acid sequences of antibody mimetics molecules, monobodies, capable of interacting with the nucleocapsid protein of the SARS-CoV virus, were taken from the literature. Nucleotide sequences of monobody genes were obtained by gene synthesis,
Autor:
Alexander S. Sobolev, Andrey A. Rosenkranz, Tatiana S. Karyagina, Yuri V. Khramtsov, Georgii P. Georgiev, Alexey V. Ulasov, Tatiana A. Slastnikova, T. N. Lupanova
Publikováno v:
Doklady Biochemistry and Biophysics. 490:22-24
New recombinant carriers-modular nanotransporters (MNTs)-with N-terminal ligand module to the epidermal growth factor receptor (EGFR) were developed and characterized. Human epidermal growth factor (hEGF) and antibody-like protein Z1907 were used as
Autor:
Yuri V. Khramtsov, Tatiana S. Karyagina, Alexander S. Sobolev, Andrey A. Rosenkranz, Alexey V. Ulasov, Georgii P. Georgiev, Tatiana A. Slastnikova, T. N. Lupanova
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Since cell nucleus is one of the most vulnerable compartments, the maximum therapeutic effect from a variety of locally acting agents, such as photosensitizers, alfa-emitters, Auger electron emitters, will be expected when they get there. Therefore,
Autor:
I. A. Gritskova, T. N. Lupanova, S. A. Gusev, A. V. Bakhtina, Tatiana Ismagulova, N. V. Bulushova, M. Kh. Khaddazh, O. A. Zhuravliova, Konstantin V. Shaitan, T. A. Voeikova, V. G. Debabov
Publikováno v:
Molecular Genetics, Microbiology and Virology. 33:233-240
Nanoparticles of cadmium sulfide (NpCdS) and zinc sulfide (NpZnS) are shown to be formed in the presence of Shewanella oneidensis MR-1 bacteria. These nanoparticles were located in the culture liquid and had a spherical shape. The nanoparticles were
Autor:
Alexander S. Sobolev, Andrey A. Rosenkranz, Yuri V. Khramtsov, Alexey V. Ulasov, A. D. Tsvetkova, Tatiana A. Slastnikova, T. N. Lupanova, Georgii P. Georgiev
Publikováno v:
Doklady Biochemistry and Biophysics. 479:62-65
We studied the possibility of optimizing modular nanotransporters (MNTs) for the intracellular delivery of antibody fragments into the nuclei of cells of a specified type. Basic MNT with a reduced size retaining the desired functions was obtained, an
Autor:
V. G. Debabov, Tatiana Ismagulova, T. A. Voeikova, T. N. Lupanova, N. V. Bulushova, Konstantin V. Shaitan, O. A. Zhuravliova, V. P. Veiko
Publikováno v:
Molecular Genetics, Microbiology and Virology. 32:204-211
A comparative analysis of the amount and composition of the proteins adsorbed onto the surface of silver-sulfide (NpAg2S) nanoparticles obtained by biosynthesis using bacteria was carried out for the first time. These were the gram-negative bacteria
Autor:
V.M. Petriev, Alexander S. Sobolev, Tatiana A. Slastnikova, Maria S Vorontsova, T. N. Lupanova, Michael R. Zalutsky, N. B. Morozova, Raisa I. Yakubovskaya, Alexey V. Ulasov, Andrey A. Rosenkranz
Publikováno v:
International Journal of Nanomedicine. 12:395-410
Purpose Modular nanotransporters (MNTs) are a polyfunctional platform designed to achieve receptor-specific delivery of short-range therapeutics into the cell nucleus by receptor-mediated endocytosis, endosome escape, and targeted nuclear transport.
Autor:
O. A. Zhuravliova, T. A. Voeikova, M. H. Khaddazh, N. V. Bulushova, T. T. Ismagulova, A. V. Bakhtina, S. A. Gusev, I. A. Gritskova, T. N. Lupanova, K. V. Shaitan, V. G. Debabov
Publikováno v:
Molecular Genetics Microbiology and Virology (Russian version). 36:191