Zobrazeno 1 - 10
of 23
pro vyhledávání: '"T. N. Bhat"'
Autor:
T. N. Bhat
Publikováno v:
Journal of Health Management. 16:113-131
The present study examined the performance of MCH programmes relative to the development of primary health care systems in Karnataka state. The study focused its analysis on the institutional development of primary health care systems, namely, Sub-Ce
Autor:
John W. Erickson, Donald Hupe, Eric T. Baldwin, J. R. Rubin, and Sergei V. Gulnik, Christine Humblet, Susan Elizabeth Hagen, Christopher Gajda, Harriet W. Hamilton, Carolyn Nouhan, Beishan Liu, J. V. N. Vara Prasad, Neil Graham, Edmund L. Ellsworth, Peter J. Tummino, John M. Domagala, Alexander Pavlovsky, Donna Ferguson, Elizabeth A. Lunney, T. N. Bhat, Bradley Dean Tait, Stephen J. Gracheck
Publikováno v:
Journal of Medicinal Chemistry. 40:3781-3792
The 4-hydroxy-5,6-dihydropyrone template was utilized as a flexible scaffolding from which to build potent active site inhibitors of HIV protease. Dihydropyrone 1c (5,6-dihydro-4-hydroxy-6-phenyl-3-[(2-phenylethyl)thio]-2H-pyran-2-one) was modeled in
Autor:
T. N. Bhat
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 46:735-742
A procedure to improve phases by a Metropolis-like algorithm (MLA) in reciprocal space is presented. It uses a density modification method (DMM) in a MLA to evaluate progress and to suggest changes to phase angles. First, in the neighborhood of the t
Autor:
T. N. Bhat, H. L. Ammon
Publikováno v:
Acta Crystallographica Section C Crystal Structure Communications. 46:112-116
C10H8F4N10O18, Mr = 632.22, monoclinic, Pc, a = 7.8885 (6), b = 6.7787 (4), c = 21.595 (2) A, beta = 108.21 (1) degree, V = 1096 (1) A3, Z = 2, Dx = 1.914 g cm-3, lambda(Cu K alpha) = 1.5418 A, mu = 18.7 cm-1, F(000) = 636, T = 293 K, 1791 unique dat
Publikováno v:
Nature structural biology.
The PDB has created systems for the processing, exchange, query, and distribution of data that will enable many aspects of high throughput structural genomics.
Autor:
John W. Erickson, Christopher Jones, Dong Xie, Nikolaus Mueller-Lantzsch, Elena Gustschina, Sergei V. Gulnik, Marlies Sauter, Christine Debouck, Terry R. Sumpter, T. N. Bhat, Nicole Robertson, Eric M. Towler
Publikováno v:
Biochemistry. 37(49)
To investigate the biochemical properties of the protease encoded by the human endogenous retrovirus, K10 (HERV-K), 213 amino acids of the 3'-end of the HERV-K protease (PR) open reading frame were expressed in Escherichia coli. Autocatalytic cleavag
Autor:
Stephen F. Martin, S V Gulnik, Horst Kessler, I A Topol, T Gane, T N Bhat, Michael C. Hillier, Barbara Mathä, G. O. Dorsey, S. Munshi, M Baur, John W. Erickson
Publikováno v:
Journal of medicinal chemistry. 41(10)
Toward establishing the general efficacy of using trisubstituted cyclopropanes as peptide mimics to stabilize extended peptide structures, the cyclopropanes 20a-d were incorporated as replacements into 9-13, which are analogues of the known HIV-1 pro
Publikováno v:
Advances in experimental medicine and biology. 436
Publikováno v:
Aspartic Proteinases ISBN: 9781461374527
Aspartic proteases have been the subject of intensive physicochemical research in the areas of catalytic mechanism, three-dimensional structure, zymogen activation and substrate specificity.1,2 The important roles of various members of this family in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9404427c5d0ff1a4f2beab9ef3f1dbd1
https://doi.org/10.1007/978-1-4615-5373-1_53
https://doi.org/10.1007/978-1-4615-5373-1_53
Publikováno v:
Advances in experimental medicine and biology. 362