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pro vyhledávání: '"T. Mischki"'
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Autor:
S. St‐Onge, T. Mischki, William Brown, Page Daniel, Ralf Schmidt, A. McClory, M. Labarre, J. Butterworth, K. Payza
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:167-170
A series of Dmt-Tic analogues with substitution on the Tic aromatic ring has been synthesized and evaluated for opioid receptor affinity and activation. Incorporation of large hydrophobic groups at position 7 of Tic did not greatly alter the delta op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85590ea597050fbc693c033c70be7204
https://doi.org/10.1016/s0960-894x(99)00652-6
https://doi.org/10.1016/s0960-894x(99)00652-6
Autor:
Rubin Ma, Jean Lapointe, Heping Ding, G. Lopinski, W. Sinclair, Adam Densmore, Boris Lamontagne, R. MacKenzie, Robert Halir, Dan-Xia Xu, H. McIntosh, Martin Vachon, T. Mischki, Y. Li, D. Desrosiers, N. Sabourin, E. Post, Pavel Cheben, Andre Delage, Siegfried Janz, Q. Y. Liu, Jens H. Schmid, Íñigo Molina-Fernández
Publikováno v:
2011 ICO International Conference on Information Photonics.
Photonic wire evanescent field (PWEF) sensor chips have been developed for multiplexed label free molecular detection. The sensors are made using 260 nm ×450 nm cross-section silicon waveguides folded into spirals less than 200 μm in diameter, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aca8d27a52a321aa7642b578b33d5d82
https://doi.org/10.1109/ico-ip.2011.5953736
https://doi.org/10.1109/ico-ip.2011.5953736
Autor:
Boris Lamontagne, T. Mischki, Y. Li, Íñigo Molina-Fernández, N. Sabourin, André Delâge, R. MacKenzie, Rubin Ma, Robert Halir, Jens H. Schmid, G. Lopinski, Jean Lapointe, Martin Vachon, Adam Densmore, E. Post, W. Sinclair, Siegfried Janz, Pavel Cheben, Dan-Xia Xu, Q. Y. Liu
Publikováno v:
SPIE Proceedings.
We are developing a photonic wire evanescent field (PWEF) sensor chip using 260 nm x 450 nm cross-section silicon photonic wire waveguides. The waveguide mode is strongly localized near the silicon surface, so that light interacts strongly with molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4da8351358f3ac9204db76703e370d59
https://doi.org/10.1117/12.875471
https://doi.org/10.1117/12.875471
Autor:
William Brown, J. Butterworth, S. St‐Onge, Ralf Schmidt, K. Payza, Page Daniel, A. McClory, T. Mischki, M. Labarre
Publikováno v:
ChemInform. 31
A series of Dmt-Tic analogues with substitution on the Tic aromatic ring has been synthesized and evaluated for opioid receptor affinity and activation. Incorporation of large hydrophobic groups at position 7 of Tic did not greatly alter the delta op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae68b4b2046268af87655fec24f795cc
https://doi.org/10.1002/chin.200021187
https://doi.org/10.1002/chin.200021187
Autor:
Pavel Cheben, Philip Waldron, Siegfried Janz, Jean Lapointe, C. Storey, Dan-Xia Xu, E. Post, Jens H. Schmid, Adam Densmore, Andre Delage, G. Lopinski, T. Mischki
Photonics is playing an increasingly important role in the field of medical diagnostics, genomics and drug discovery. With the advances in molecular biology which gives insight to the processes underlying diseases and drug response, there is a need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8431f07575f21c02c3498ba46d2364
https://nrc-publications.canada.ca/eng/view/object/?id=37e0aa8b-d6a1-47df-9d65-97e90dd3a1f1
https://nrc-publications.canada.ca/eng/view/object/?id=37e0aa8b-d6a1-47df-9d65-97e90dd3a1f1
Autor:
W. Sinclair, Martin Vachon, Dan-Xia Xu, Rubin Ma, Boris Lamontagne, T. Mischki, Y. Li, E. Post, Jean Lapointe, Jens H. Schmid, Siegfried Janz, Pavel Cheben, Adam Densmore, G. Lopinski, Andre Delage
Publikováno v:
2009 6th IEEE International Conference on Group IV Photonics.
Silicon photonic wire waveguides have a remarkably high response to surface molecular binding. Evanescent field waveguide sensors based on silicon can be interrogated using Mach-Zehnder interferometers, ring resonators, or by probing surface gratings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::214d75ce4aa32f73d7e0fe6e6760dc69
https://doi.org/10.1109/group4.2009.5338350
https://doi.org/10.1109/group4.2009.5338350
Autor:
André Delâge, Philip Waldron, T. Mischki, Jean Lapointe, G. Lopinski, Jens H. Schmid, Martin Vachon, Siegfried Janz, Pavel Cheben, Rubin Ma, Adam Densmore, D.-X. Xu
Publikováno v:
SPIE Proceedings.
We review our work developing label-free molecular sensors using silicon nanophotonic waveguides. We show that the high index contrast of these waveguides provides high surface sensitivity and enables compact sensor designs to be realized. We also de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65f724794f1a79804c5f4b8b5a279a68
https://doi.org/10.1117/12.811602
https://doi.org/10.1117/12.811602
Autor:
S. Janz, A. Densmore, D.-X. Xu, P. Waldron, J. Lapointe, J. H. Schmid, T. Mischki, G. Lopinski, A. Delâge, R. McKinnon, P. Cheben, B. Lamontagne
Publikováno v:
Integrated Analytical Systems ISBN: 9780387980607
Methods and devices relating to a sensor for use in detecting and monitoring molecular interactions. A silicon waveguide sensing element is provided along with a layer of silicon. A silicon oxide layer is also provided between the waveguide element a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26691d00b08dbe0ee97db0560ed07407
https://doi.org/10.1007/978-0-387-98063-8_9
https://doi.org/10.1007/978-0-387-98063-8_9
Autor:
Jean Lapointe, Pavel Cheben, André Delâge, W. Sinclair, Dan-Xia Xu, Siegfried Janz, Daniel Poitras, Jens H. Schmid, Adam Densmore, T. Mischki, Philip Waldron, Gregory P. Lopinski
Publikováno v:
Advances in Optical Sciences Congress.
We present experimental and theoretical results of label-free molecular sensing with the TM mode of a 0.22 µm thick silicon slab waveguide used in a guided mode resonance configuration. Due to the strong overlap of the evanescent field of the wavegu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8ef3460dc3837c86607e2017340b33
https://doi.org/10.1364/ipnra.2009.iwb3
https://doi.org/10.1364/ipnra.2009.iwb3