Zobrazeno 1 - 10
of 440
pro vyhledávání: '"T. Melvin"'
Autor:
D. E. Sergeev, N. J. Mayne, T. Bendall, I. A. Boutle, A. Brown, I. Kavčič, J. Kent, K. Kohary, J. Manners, T. Melvin, E. Olivier, L. K. Ragta, B. Shipway, J. Wakelin, N. Wood, M. Zerroukat
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 5601-5626 (2023)
We demonstrate that LFRic-Atmosphere, a model built using the Met Office's GungHo dynamical core, is able to reproduce idealised large-scale atmospheric circulation patterns specified by several widely used benchmark recipes. This is motivated by the
Externí odkaz:
https://doaj.org/article/13b0bc1f0be04c798b54b89be9672ea5
Publikováno v:
Geoscientific Model Development, Vol 16, Pp 1265-1276 (2023)
This paper introduces a mixed finite-element shallow-water model on the sphere. The mixed finite-element approach is used as it has been shown to be both accurate and highly scalable for parallel architecture. Key features of the model are an iterate
Externí odkaz:
https://doaj.org/article/e2d1ac7828474f1bbeee365424bbb9b9
Autor:
D. Walters, I. Boutle, M. Brooks, T. Melvin, R. Stratton, S. Vosper, H. Wells, K. Williams, N. Wood, T. Allen, A. Bushell, D. Copsey, P. Earnshaw, J. Edwards, M. Gross, S. Hardiman, C. Harris, J. Heming, N. Klingaman, R. Levine, J. Manners, G. Martin, S. Milton, M. Mittermaier, C. Morcrette, T. Riddick, M. Roberts, C. Sanchez, P. Selwood, A. Stirling, C. Smith, D. Suri, W. Tennant, P. L. Vidale, J. Wilkinson, M. Willett, S. Woolnough, P. Xavier
Publikováno v:
Geoscientific Model Development, Vol 10, Iss 4, Pp 1487-1520 (2017)
We describe Global Atmosphere 6.0 and Global Land 6.0 (GA6.0/GL6.0): the latest science configurations of the Met Office Unified Model and JULES (Joint UK Land Environment Simulator) land surface model developed for use across all timescales. Global
Externí odkaz:
https://doaj.org/article/b210587f793c4832b86924f17075d9f5
Autor:
Braulio Andrés Ortega Quesada, Jonathan Cuccia, Rachael Coates, Blake Nassar, Ethan Littlefield, Elizabeth C. Martin, Adam T. Melvin
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Metastatic breast cancer leads to poor prognoses and worse outcomes in patients due to its invasive behavior and poor response to therapy. It is still unclear what biophysical and biochemical factors drive this more aggressive phenotype in m
Externí odkaz:
https://doaj.org/article/f519056d380b4637a7b66f084dcd6638
Loss of Hormone Receptor Expression after Exposure to Fluid Shear Stress in Breast Cancer Cell Lines
Autor:
Jonathan Cuccia, Braulio Andrés Ortega Quesada, Ethan P. Littlefield, Alejandra M. Ham, Matthew E. Burow, Adam T. Melvin, Elizabeth C. Martin
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7119 (2024)
Following metastatic spread, many hormone receptor positive (HR+) patients develop a more aggressive phenotype with an observed loss of the HRs estrogen receptor (ER) and progesterone receptor (PR). During metastasis, breast cancer cells are exposed
Externí odkaz:
https://doaj.org/article/d7ea84a9d35f4761af3e3ba19d538355
Autor:
Hannah C. Hymel, Alireza Rahnama, Olivia M. Sanchez, Dong Liu, Ted J. Gauthier, Adam T. Melvin
Publikováno v:
Cells, Vol 11, Iss 7, p 1195 (2022)
Cell-penetrating peptides (CPPs) have emerged as a powerful tool for the delivery of otherwise impermeable cargoes into intact cells. Recent efforts to improve the delivery capability of peptides have mainly focused on the identity of the CPP; howeve
Externí odkaz:
https://doaj.org/article/ecfeeebe999a41eb8554b09aa21664b8
Autor:
Anowar H. Khan, Sophia P. Zhou, Margaret Moe, Braulio A. Ortega Quesada, Khashayar R. Bajgiran, Haley R. Lassiter, James A. Dorman, Elizabeth C. Martin, John A. Pojman, Adam T. Melvin
Publikováno v:
ACS Biomaterials Science & Engineering. 8:3977-3985
Culturing cancer cells in a three-dimensional (3D) environment better recapitulatesiin vivo/iconditions by mimicking cell-to-cell interactions and mass transfer limitations of metabolites, oxygen, and drugs. Recent drug studies have suggested that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597355bf8b6d5a0c43f8d11a10110123
https://doi.org/10.1021/acsbiomaterials.2c00491
https://doi.org/10.1021/acsbiomaterials.2c00491
Autor:
Gabela Nelson, Alexis Strain, Atsuko Isu, Alireza Rahnama, Ken-ichi Wakabayashi, Adam T. Melvin, Naohiro Kato
The mechanisms governing chemotaxis in Chlamydomonas reinhardtii are largely unknown compared to those regulating phototaxis despite equal importance on the migratory response in the ciliated microalga. To study chemotaxis, we developed a simple Petr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f30761e389a57bbb8a0c4b7636194c78
https://doi.org/10.21203/rs.3.rs-2420572/v1
https://doi.org/10.21203/rs.3.rs-2420572/v1
Autor:
Natalia da Silva Moura, Khashayar R. Bajgiran, Adam T. Melvin, Kerry M. Dooley, James A. Dorman
Publikováno v:
ACS Applied Nano Materials. 4:13778-13787
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e056ef76fcd09ba450b53bd08c6d8d90
https://doi.org/10.1021/acsanm.1c03168
https://doi.org/10.1021/acsanm.1c03168
Autor:
Martina T. Melvin, Naveed T. Siddiqui, Evan Wild, Matteo Parotto, Vsevolod S. Perelman, Kong Eric You-Ten
Publikováno v:
Anesthesia and analgesia.
The high-fidelity ORSIM (Airway Simulation Ltd) and the low-fidelity wooden-block fiber-optic task trainers allow users to familiarize themselves with the psychomotor skills required to manipulate the fiber-optic scope.This single-center study aimed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb937d17c9d7f07712b2220eed8e35e
https://pubmed.ncbi.nlm.nih.gov/36445843
https://pubmed.ncbi.nlm.nih.gov/36445843