Zobrazeno 1 - 10
of 514
pro vyhledávání: '"T. Meister"'
Autor:
Ferdinand W. Janssen, Nathalie S. M. Lak, Claudia Y. Janda, Lennart A. Kester, Michael T. Meister, Johannes H. M. Merks, Marry M. van den Heuvel-Eibrink, Max M. van Noesel, Jozsef Zsiros, Godelieve A. M. Tytgat, Leendert H. J. Looijenga
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-25 (2024)
Abstract Liquid biopsies are emerging as an alternative source for pediatric cancer biomarkers with potential applications during all stages of patient care, from diagnosis to long-term follow-up. While developments within this field are reported, th
Externí odkaz:
https://doaj.org/article/7e228ee58b924504a47bb48758ddcf6e
Autor:
Jeff DeMartino, Michael T. Meister, Lindy L. Visser, Mariël Brok, Marian J. A. Groot Koerkamp, Amber K. L. Wezenaar, Laura S. Hiemcke-Jiwa, Terezinha de Souza, Johannes H. M. Merks, Anne C. Rios, Frank C. P. Holstege, Thanasis Margaritis, Jarno Drost
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive treatment regimens, the prognosis for high-risk patients re
Externí odkaz:
https://doaj.org/article/6e17129946ec4b3cabd8153ddce619c9
Autor:
Denise A. Pfefferle, Michael Hackett, Michael S. Anderson, Seth Gibbs, Lisa N. Henning, April C. Joice, Gabriel T. Meister
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Melioidosis is an endemic disease in numerous tropical regions. Additionally, the bacterium that causes melioidosis, Burkholderia pseudomallei, has potential to be used as a biological weapon. Therefore, development of effective and affordab
Externí odkaz:
https://doaj.org/article/ca4f65a1ceed484a88d6eb78a8e40e1d
Autor:
Catrin Heim, Laura M. Moser, Herman Kreyenberg, Halvard B. Bonig, Torsten Tonn, Winfried S. Wels, Elise Gradhand, Evelyn Ullrich, Michael T. Meister, Marian Groot Koerkamp, Frank C. P. Holstege, Jarno Drost, Jan-Henning Klusmann, Peter Bader, Michael Merker, Eva Rettinger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionMetastatic rhabdomyosarcoma (RMS) is a challenging tumor entity that evades conventional treatments and endogenous antitumor immune responses, highlighting the need for novel therapeutic strategies. Applying chimeric antigen receptor (CAR
Externí odkaz:
https://doaj.org/article/a67ec3b12510448385698d63f9fbce7d
Autor:
Ufuk Erdogdu, Nadezda Dolgikh, Stephanie Laszig, Vinzenz Särchen, Michael T. Meister, Marek Wanior, Stefan Knapp, Cathinka Boedicker
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 24, Iss 2, Pp 109-119 (2022)
BH3 mimetics are promising novel anticancer therapeutics. By selectively inhibiting BCL-2, BCL-xL, or MCL-1 (i.e. ABT-199, A-1331852, S63845) they shift the balance of pro- and anti-apoptotic proteins in favor of apoptosis. As Bromodomain and Extra T
Externí odkaz:
https://doaj.org/article/0403c2302550453288f621f27f8c9d7f
Autor:
Michael T Meister, Marian J A Groot Koerkamp, Terezinha deSouza, Willemijn B Breunis, Ewa Frazer‐Mendelewska, Mariël Brok, Jeff DeMartino, Freek Manders, Camilla Calandrini, Hinri H D Kerstens, Alex Janse, M Emmy M Dolman, Selma Eising, Karin P S Langenberg, Marc vanTuil, Rutger R G Knops, Sheila Terwisscha vanScheltinga, Laura S Hiemcke‐Jiwa, Uta Flucke, Johannes H M Merks, Max M vanNoesel, Bastiaan B J Tops, Jayne Y Hehir‐Kwa, Patrick Kemmeren, Jan J Molenaar, Marc van deWetering, Ruben vanBoxtel, Jarno Drost, Frank C P Holstege
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 10, Pp n/a-n/a (2022)
Abstract Rhabdomyosarcomas (RMS) are mesenchyme‐derived tumors and the most common childhood soft tissue sarcomas. Treatment is intense, with a nevertheless poor prognosis for high‐risk patients. Discovery of new therapies would benefit from addi
Externí odkaz:
https://doaj.org/article/bfe59c6efb18489cb65ad4d76f02464c
Autor:
Marcellene A. Gates-Hollingsworth, Cari B. Kolton, Alex R. Hoffmaster, Gabriel T. Meister, Addie E. Moore, Heather R. Green, Janice M. Pogoda, Segaran P. Pillai, Thomas R. Kozel
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Inhalational anthrax is a fatal infectious disease. Rapid and effective treatment is critically dependent on early and accurate diagnosis. Blood culture followed by identification and confirmation may take days to provide clinically relevant
Externí odkaz:
https://doaj.org/article/e673fdf6e0ea4433bf8f8a312a87bc9c
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary Staples, Benjamin Klaffke, Gloria F. Rodriguez, Priscilla Escareno, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton III, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Vaccines, Vol 10, Iss 10, p 1723 (2022)
The primary objective of this study was to characterize the disease course in cynomolgus macaques exposed to Sudan virus (SUDV), to determine if infection in this species is an appropriate model for the evaluation of filovirus countermeasures under t
Externí odkaz:
https://doaj.org/article/2cc1aa54e7954ee49dfdea798a0267ee
Autor:
Kendra J. Alfson, Yenny Goez-Gazi, Michal Gazi, Ying-Liang Chou, Nancy A. Niemuth, Marc E. Mattix, Hilary M. Staples, Benjamin Klaffke, Gloria F. Rodriguez, Carmen Bartley, Anysha Ticer, Elizabeth A. Clemmons, John W. Dutton, Anthony Griffiths, Gabe T. Meister, Daniel C. Sanford, Chris M. Cirimotich, Ricardo Carrion
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1314 (2022)
Marburg virus (MARV) is a filovirus that can infect humans and nonhuman primates (NHPs), causing severe disease and death. Of the filoviruses, Ebola virus (EBOV) has been the primary target for vaccine and therapeutic development. However, MARV has a
Externí odkaz:
https://doaj.org/article/21c882aa05dc43e9936872174f3053a7
Autor:
Isabelle S. A. de Vries, Roelof van Ewijk, Laura M. E. Adriaansen, Anneloes E. Bohte, Arthur J. A. T. Braat, Raquel Dávila Fajardo, Laura S. Hiemcke-Jiwa, Marinka L. F. Hol, Simone A. J. ter Horst, Bart de Keizer, Rutger R. G. Knops, Michael T. Meister, Reineke A. Schoot, Ludi E. Smeele, Sheila Terwisscha van Scheltinga, Bas Vaarwerk, Johannes H. M. Merks, Rick R. van Rijn
Publikováno v:
Pediatric Radiology. 53:788-812
Rhabdomyosarcoma, although rare, is the most frequent soft tissue sarcoma in children and adolescents. It can present as a mass at nearly any site in the body, with most common presentations in the head and neck, genitourinary tract and extremities.