Zobrazeno 1 - 10
of 651
pro vyhledávání: '"T. McMillan"'
Autor:
Max A. Laansma, Yuji Zhao, Eva M. van Heese, Joanna K. Bright, Conor Owens-Walton, Sarah Al-Bachari, Tim J. Anderson, Francesca Assogna, Tim D. van Balkom, Henk W. Berendse, Fernando Cendes, John C. Dalrymple-Alford, Ines Debove, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Jean-Paul Fouche, Gaëtan Garraux, Rachel P. Guimarães, Rick C. Helmich, Michele Hu, Odile A. van den Heuvel, Dmitry Isaev, Ho-Bin Kim, Johannes C. Klein, Christine Lochner, Corey T. McMillan, Tracy R. Melzer, Benjamin Newman, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Toni L. Pitcher, Kathleen L. Poston, Mario Rango, Leticia F. Ribeiro, Cristiane S. Rocha, Christian Rummel, Lucas S. R. Santos, Reinhold Schmidt, Petra Schwingenschuh, Letizia Squarcina, Dan J. Stein, Daniela Vecchio, Chris Vriend, Jiunjie Wang, Daniel Weintraub, Roland Wiest, Clarissa L. Yasuda, Neda Jahanshad, Paul M. Thompson, Ysbrand D. van der Werf, Boris A. Gutman
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Alterations in subcortical brain regions are linked to motor and non-motor symptoms in Parkinson’s disease (PD). However, associations between clinical expression and regional morphological abnormalities of the basal ganglia, thalamus, amy
Externí odkaz:
https://doaj.org/article/0ad01d15502c49b4bbf825957015ee01
Autor:
Conor Owens-Walton, Talia M. Nir, Sarah Al-Bachari, Sonia Ambrogi, Tim J. Anderson, Ítalo Karmann Aventurato, Fernando Cendes, Yao-Liang Chen, Valentina Ciullo, Phil Cook, John C. Dalrymple-Alford, Michiel F. Dirkx, Jason Druzgal, Hedley C. A. Emsley, Rachel Guimarães, Hamied A. Haroon, Rick C. Helmich, Michele T. Hu, Martin E. Johansson, Ho Bin Kim, Johannes C. Klein, Max Laansma, Katherine E. Lawrence, Christine Lochner, Clare Mackay, Corey T. McMillan, Tracy R. Melzer, Leila Nabulsi, Ben Newman, Peter Opriessnig, Laura M. Parkes, Clelia Pellicano, Fabrizio Piras, Federica Piras, Lukas Pirpamer, Toni L. Pitcher, Kathleen L. Poston, Annerine Roos, Lucas Scárdua Silva, Reinhold Schmidt, Petra Schwingenschuh, Marian Shahid-Besanti, Gianfranco Spalletta, Dan J. Stein, Sophia I. Thomopoulos, Duygu Tosun, Chih-Chien Tsai, Odile A. van den Heuvel, Eva van Heese, Daniela Vecchio, Julio E. Villalón-Reina, Chris Vriend, Jiun-Jie Wang, Yih-Ru Wu, Clarissa Lin Yasuda, Paul M. Thompson, Neda Jahanshad, Ysbrand van der Werf
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-12 (2024)
Abstract The progression of Parkinson’s disease (PD) is associated with microstructural alterations in neural pathways, contributing to both motor and cognitive decline. However, conflicting findings have emerged due to the use of heterogeneous met
Externí odkaz:
https://doaj.org/article/abdb13d4596d46599f5bc49288648bf9
Autor:
Michael Benatar, Eric A. Macklin, Andrea Malaspina, Mary-Louise Rogers, Eran Hornstein, Vittoria Lombardi, Danielle Renfrey, Stephanie Shepheard, Iddo Magen, Yahel Cohen, Volkan Granit, Jeffrey M. Statland, Jeannine M. Heckmann, Rosa Rademakers, Caroline A. McHutchison, Leonard Petrucelli, Corey T. McMillan, Joanne Wuu, Lauren Elman, John Ravits, Jonathan Katz, Jaya Trivedi, Andrea Swenson, Ted M. Burns, James Caress, Carlayne Jackson, Samuel Maiser, Erik P. Pioro, Yuen So
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105323- (2024)
Summary: Background: With increasing recognition of the value of incorporating prognostic markers into amyotrophic lateral sclerosis (ALS) trial design and analysis plans, there is a pressing need to understand which among the prevailing clinical and
Externí odkaz:
https://doaj.org/article/e1d4a293db1a412aa52ac92f571d2d19
Autor:
Sylvia Mihailescu, Quinn Hlava, Philip A. Cook, Maria Luisa Mandelli, Suzee E. Lee, Bradley F. Boeve, Bradford C. Dickerson, Maria Luisa Gorno-Tempini, Emily Rogalski, Murray Grossman, James Gee, Corey T. McMillan, Christopher A. Olm
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionFrontotemporal lobar degeneration (FTLD) is associated with FTLD due to tau (FTLD-tau) or TDP (FTLD-TDP) inclusions found at autopsy. Arterial Spin Labeling (ASL) MRI is often acquired in the same session as a structural T1-weighted image
Externí odkaz:
https://doaj.org/article/df95660fbdbd499fb260b1ca808d1d37
Autor:
Sanaz Arezoumandan, Katheryn A.Q. Cousins, Daniel T. Ohm, MaKayla Lowe, Min Chen, James Gee, Jeffrey S. Phillips, Corey T. McMillan, Kelvin C. Luk, Andres Deik, Meredith A. Spindler, Thomas F. Tropea, Daniel Weintraub, David A. Wolk, Murray Grossman, Virginia Lee, Alice S. Chen‐Plotkin, Edward B. Lee, David J. Irwin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 673-685 (2024)
Abstract Objective Alzheimer's disease neuropathologic change and alpha‐synucleinopathy commonly co‐exist and contribute to the clinical heterogeneity of dementia. Here, we examined tau epitopes marking various stages of tangle maturation to test
Externí odkaz:
https://doaj.org/article/cdc2ad75ef8743d99fac2e3feb9bcc6b
Autor:
Ting Shen, Jacob W. Vogel, Jeffrey Duda, Jeffrey S. Phillips, Philip A. Cook, James Gee, Lauren Elman, Colin Quinn, Defne A. Amado, Michael Baer, Lauren Massimo, Murray Grossman, David J. Irwin, Corey T. McMillan
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-20 (2023)
Abstract Background TDP-43 proteinopathies represent a spectrum of neurological disorders, anchored clinically on either end by amyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD). The ALS–FTD spectrum exhibits a diverse range
Externí odkaz:
https://doaj.org/article/2b11c89bb7724f18adf67758d44d34c1
Autor:
Jeffrey S. Phillips, Nagesh Adluru, Moo K. Chung, Hamsanandini Radhakrishnan, Christopher A. Olm, Philip A. Cook, James C. Gee, Katheryn A. Q. Cousins, Sanaz Arezoumandan, David A. Wolk, Corey T. McMillan, Murray Grossman, David J. Irwin
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionMultimodal evidence indicates Alzheimer’s disease (AD) is characterized by early white matter (WM) changes that precede overt cognitive impairment. WM changes have overwhelmingly been investigated in typical, amnestic mild cognitive imp
Externí odkaz:
https://doaj.org/article/982254d1016246fcba223287b0b73d9f
Autor:
Alba Cervantes González, David J. Irwin, Daniel Alcolea, Corey T. McMillan, Alice Chen-Plotkin, David Wolk, Sònia Sirisi, Oriol Dols-Icardo, Marta Querol-Vilaseca, Ignacio Illán-Gala, Miguel Angel Santos-Santos, Juan Fortea, Edward B. Lee, John Q. Trojanowski, Murray Grossman, Alberto Lleó, Olivia Belbin
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Background Synapse degeneration is an early event in pathological frontotemporal lobar degeneration (FTLD). Consequently, a surrogate marker of synapse loss could be used to monitor early pathologic changes in patients with underlying FTLD.
Externí odkaz:
https://doaj.org/article/9e38617f0aad47289a4630d1dc7afd9a
Autor:
Nicolai Franzmeier, Matthias Brendel, Leonie Beyer, Luna Slemann, Gabor G. Kovacs, Thomas Arzberger, Carolin Kurz, Gesine Respondek, Milica J. Lukic, Davina Biel, Anna Rubinski, Lukas Frontzkowski, Selina Hummel, Andre Müller, Anika Finze, Carla Palleis, Emanuel Joseph, Endy Weidinger, Sabrina Katzdobler, Mengmeng Song, Gloria Biechele, Maike Kern, Maximilian Scheifele, Boris-Stephan Rauchmann, Robert Perneczky, Michael Rullman, Marianne Patt, Andreas Schildan, Henryk Barthel, Osama Sabri, Jost J. Rumpf, Matthias L. Schroeter, Joseph Classen, Victor Villemagne, John Seibyl, Andrew W. Stephens, Edward B. Lee, David G. Coughlin, Armin Giese, Murray Grossman, Corey T. McMillan, Ellen Gelpi, Laura Molina-Porcel, Yaroslau Compta, John C. van Swieten, Laura Donker Laat, Claire Troakes, Safa Al-Sarraj, John L. Robinson, Sharon X. Xie, David J. Irwin, Sigrun Roeber, Jochen Herms, Mikael Simons, Peter Bartenstein, Virginia M. Lee, John Q. Trojanowski, Johannes Levin, Günter Höglinger, Michael Ewers
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Tau pathology drives neuronal dysfunction in 4- repeat tauopathies. Here, the authors combine tau-PET, resting-state fMRI and histopathology data, to show that brain connectivity is associated with tau deposition patterns in 4-repeat tauopathies.
Externí odkaz:
https://doaj.org/article/bd1a4c237aa0450eb6ad79b56669c4c6
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0287112 (2023)
Racial disparities in many aging-related health outcomes are persistent and pervasive among older Americans, reflecting accelerated biological aging for Black Americans compared to White, known as weathering. Environmental determinants that contribut
Externí odkaz:
https://doaj.org/article/868b6364fd4741108d0a0bb29bf72583