Zobrazeno 1 - 10
of 240
pro vyhledávání: '"T. Malmfors"'
Publikováno v:
Scandinavian Journal of Haematology. 19:87-98
Four groups of Sprague-Dawley rats were given Ferastral®, an iron-poly (sorbitol-gluconic acid) complex (IPSG) or Imferon®, an iron-dextran complex, intramuscularly twice a week for 17 weeks. The experiment lasted for 95 weeks. Each compound was gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1a83578db60e2693c23833d61b4d80
https://doi.org/10.1111/j.1600-0609.1977.tb01220.x
https://doi.org/10.1111/j.1600-0609.1977.tb01220.x
Publikováno v:
Scandinavian Journal of Haematology. 19:58-68
This paper presents a review of the toxicological studies in animals on Ferastral®, an iron-poly (sorbitol-gluconic acid) complex. Studies after single administration were performed in mice, rats and dogs, and LD50-values were calculated in mice and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d654c2e837c61bb6972fe680669b9059
https://doi.org/10.1111/j.1600-0609.1977.tb01217.x
https://doi.org/10.1111/j.1600-0609.1977.tb01217.x
Publikováno v:
Acta Pharmacologica et Toxicologica. 36:96-103
This paper presents a review of the toxicological studies in animals on metoprolol - a cardioselective β-blocking agent. Studies after single administration were performed in mice, rats and dogs. LD50-values were calculated for the rodents while max
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2be5ce3c9a98e1ac5e87626e902561
https://doi.org/10.1111/j.1600-0773.1975.tb03326.x
https://doi.org/10.1111/j.1600-0773.1975.tb03326.x
Autor:
T. Malmfors, Carl-Gunnar Regårdh, G. Johnsson, Enar Carlsson, Lars Ek, Karl Olof Borg, Bengt Åblad
Publikováno v:
Acta Pharmacologica et Toxicologica. 36:7-23
Studies in both animals and man have shown that metoprolol is a β1-selective adrenergic receptor antagonist devoid of betamimetic activity. The cardiac stimulant effect of isoprenaline is markedly inhibited by metoprolol in doses that only slightly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dae7895e65380357bd4c1038661c7de4
https://doi.org/10.1111/j.1600-0773.1975.tb03318.x
https://doi.org/10.1111/j.1600-0773.1975.tb03318.x
Autor:
A. Teiling, T. Malmfors
Publikováno v:
Acta Pharmacologica et Toxicologica. 52:229-246
Does the pharmaceutical industry perform LD50-determinations in animals just because it is required by the authorities or are there any scientific benefits from counting dead animals and calculating and index of lethal toxicity? This is an important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf672c4f1b5bff17bf52da6b6e7334d7
https://doi.org/10.1111/j.1600-0773.1983.tb02692.x
https://doi.org/10.1111/j.1600-0773.1983.tb02692.x
Publikováno v:
Risk Analysis. 19:649-659
The concept of exposure is central to chemical risk assessment and plays an important role in communicating to the public about the potential health risks of chemicals. Research on chemical risk perception has found some indication that the model lay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7433879893b3cd3518d101fa46256536
https://doi.org/10.1111/j.1539-6924.1999.tb00435.x
https://doi.org/10.1111/j.1539-6924.1999.tb00435.x
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 54(3)
A series of chemically modified rosin resins have been tested for their potential to cause skin sensitization using the mouse LLNA. Where direct comparative evidence is available, the results of the mouse LLNA are consistent with previously obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860b662b8c33f49956e26057a4d58aaa
https://pubmed.ncbi.nlm.nih.gov/19409440
https://pubmed.ncbi.nlm.nih.gov/19409440
Autor:
T MALMFORS
Publikováno v:
Toxicology Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::030346d62483f9e081f46143eb2890c9
https://doi.org/10.1016/s0378-4274(04)00208-5
https://doi.org/10.1016/s0378-4274(04)00208-5
Autor:
H Rosing, T Malmfors
Publikováno v:
Toxicology.
In this paper it is argued that risk assessment (RA) should be based on principles of philosophy of science. However, in the field of toxicology and the associated RA this is generally not the case. The aim of this presentation is to demonstrate vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516968e44646a09d9c02b010f62b1a6c
https://pubmed.ncbi.nlm.nih.gov/12505294
https://pubmed.ncbi.nlm.nih.gov/12505294
Autor:
T. Malmfors
Publikováno v:
Pharmacology & Toxicology. 90:229-230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04fc2578078852835edf28d018753ca1
https://doi.org/10.1034/j.1600-0773.2002.900501.x
https://doi.org/10.1034/j.1600-0773.2002.900501.x