Zobrazeno 1 - 8
of 8
pro vyhledávání: '"T. M. T. Mulders"'
Autor:
Gerard J. Mulder, T. M. T. Mulders, Douwe D. Breimer, D. J. W. Bergman, Gerrit Smit, Marinus Duran, Jan A.M. Smeitink, B. T. Poll-The
Publikováno v:
Journal of inherited metabolic disease, 20(4), 473-485. Springer Netherlands
Journal of Inherited Metabolic Disease, 20, 473-485
Journal of Inherited Metabolic Disease, 20, pp. 473-485
Journal of Inherited Metabolic Disease, 20, 473-485
Journal of Inherited Metabolic Disease, 20, pp. 473-485
Previous studies have suggested that tyrosinaemia type I may be associated with reduced glutathione availability due to conjugation of tyrosinaemia-associated reactive intermediates with glutathione. In the present study, the glutathione/ glutathione
Publikováno v:
Drug Metabolism Reviews. 27:191-229
Publikováno v:
Biochemical Pharmacology. 46:1775-1780
Glutathione (GSH) conjugation of 2-bromoisovalerylurea (BIU) enantiomers is stereoselective in humans in vivo. Administration of racemic BIU results in a higher plasma elimination and urinary excretion of R-BIU and its mercapturate, respectively, tha
Publikováno v:
Human reproduction (Oxford, England). 16(3)
A novel contraceptive vaginal ring releasing etonogestrel 120 microg and ethinyl oestradiol 15 microg daily over a period of 3 weeks was tested. Each ring was used for one cycle, comprising 3 weeks of ring use followed by a 1 week ring-free period. T
Autor:
Rik C. Schoemaker, Vicki Venizelos, T. M. T. Mulders, Gerard J. Mulder, Douwe D. Breimer, Adam F. Cohen
Publikováno v:
Clinical pharmacology and therapeutics. 53(1)
Characterization of glutathione conjugation in vivo was performed in 12 healthy male volunteers by use of the racemic drug bromisovalum (bromisoval; 2-bromoisovalerylurea) as a model substrate. To study whether the pharmacokinetics of both bromisoval
Autor:
Eiji Uchida, H. C. Schoemaker, Adam F. Cohen, Douwe D. Breimer, T. M. T. Mulders, P. A. Soons
Publikováno v:
European journal of clinical pharmacology. 44(2)
The pharmacokinetics of racemic (rac) felodipine, rac-nitrendipine and nifedipine (all given as an oral dose of 20 mg in solution) have been investigated in a randomised cross-over study in 12 healthy male subjects using stereoselective assays. Both
Autor:
Gerard J. Mulder, U.R. Tjaden, Vicki Venizelos, H. Irth, J. van der Greef, Douwe D. Breimer, T. M. T. Mulders
Publikováno v:
Journal of chromatography. 573(2)
A stereoselective method has been developed for the determination of R- and S-(alpha-bromoisovaleryl)urea in plasma and saliva after oral administration. The chiral separation was carried out on Chiralcel OJ or OD columns with hexane--2-propanol as t
Autor:
H. H. G. Betendsen, C. L. E. Broekkamp, A. M. L. van Delft, M. W. Beukers, I. Meigel, H. W. G. M. Boddeke, F. D. Beusenberg, M. J. P. Adolfs, J. M. E. van Schalk, J. G. C. van Amsterdam, I. L. Bonta, H. C. H. Boonen, J. G. R. De Hey, S. F. de Boer, J. van der Gugten, R. H. de Rijk, N. van Rooyen, F. J. H. Tilders, F. Berkenbosch, P. J. F. de Vries, C. M. Tyssen, H. A. J. Struyker Boudier, J. F. M. Smits, T. J. de Vries, F. Hogenboom, A. H. Mulder, A. N. M. Schoffelmeer, B. H. W. Erdtsieck-Ernste, M. G. P. Feenstra, W. J. Florijn, Th. de Boer, J. A. D. M. Tonnaer, J. W. van Nispen, D. H. G. Versteeg, Gert Folkerts, Marc P. W. Janssen, Frans P. Nijkamp, J. Cafssen, F. P. Nijkamp, H. Van Per Vliet, H. Van Loveren, F. M. J. Heemskerk, L. H. Schrania, P. N. E. De Graan, W. E. J. M. Ghijscn, F. H. Lopes da Silva, W. H. Gispen, Menno H. Heijna, Maricke Padt, François Hopenhoom, Anton N. M. Schoffelmeer, Arie H. Mulder, J. B. Heijnis, M. -J. Mathy, P. A. van Zwieten, Ch. Hollenga, J. Zaagsma, A. Hoogerkamp, J. Dingemanse, R. A. Voskuyl, M. Danhof, A. C. E. Linthorst, H. de Lang, W. de Jong, J. W. Mandema, H. J. Tukker, M. J. F. Mertens, H. W. J. Messing, H. van Essen, H. J. M. G. Nelissen, J. H. F. Smits, Nicole G. M. Palmen, Aloys L. A. Sesink, P. Th. Henderson, Paul J. A. Borm, G. E. Ploeger, A. P. M. Willemen, A. R. Cools, J. J. Plomp, G. Th. H. van Kempen, P. C. Molenaar, Nick F. Ramsey, Jan M. van Ree, J. Riezebos, W. Vleeming, D. J. de Wildt, H. B. van Rooij, J. Memer, A. J. Porsius, A. F. Roffel, H. Meurs, C. R. S. Elzinga, E. Ronken, J. A. D. M. Tonnacr, V. M. Wicgant, P. H. H. Schiffers, H. C. M. Boonen, E. H. Dijkstra, G. E. Fazzi, M. A. J. P. Daemen, J. G. R. De Mey, P. A. Soons, A. de Boer, T. M. T. Mulders, A. F. Cohen, D. D. Breimer, J. B. M. M. van Bree, A. G. de Boer, H. Danhof, D. T. W. M. van den Berg, A. van Haarst, E. R. de Kloet, R. van den Ende, H. D. Batink, J. G. Hugtenburg, P. N. M. van Heiningen, J. A. van Hilten, C. van Krimpen, J. F. M. Smils, M. J. A. P. Daemon, F. T. Bosman, M. van Lookeren, Campagne P. Buma, A. B. Oestreicher, Marjan J. A. van Veldhuizen, Matthijs G. P. Feenstra, Gerard J. Boer, B. J. van Vliet, N. P. L. G. Verhoeff, M. Bobeldijk, E. A. van Royen, G. J. Boer, P. van Dorremalen, J. Riezehos, H. H. van Rooii, J. Wemer
Publikováno v:
Pharmaceutisch Weekblad. 11:J3-J15