Zobrazeno 1 - 10
of 10
pro vyhledávání: '"T. M. Handel"'
Autor:
Fernando R. Clemente, Jason DeChancie, K. N. Houk, T. M. Handel,† and, Hakan Gunaydin, Adam J.T. Smith, Arnab B. Chowdry, Xiyun Zhang
Publikováno v:
The Journal of Organic Chemistry. 73:889-899
The design of active sites has been carried out using quantum mechanical calculations to predict the rate-determining transition state of a desired reaction in presence of the optimal arrangement of catalytic functional groups (theozyme). Eleven vers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029efe274979deebb1d578595cde1e7c
https://doi.org/10.1021/jo701974n
https://doi.org/10.1021/jo701974n
Autor:
E C, Johnson, T M, Handel
Publikováno v:
Journal of biomolecular NMR. 15(2)
The effect of hydrophobic core packing on sidechain dynamics was analyzed by comparing the dynamics of wild-type (WT) ubiquitin to those of a variant which has seven core mutations. This variant, 1D7, was designed to resemble WT by having a well-pack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b6fe7f64b7c69dd9732780af515e81c
https://pubmed.ncbi.nlm.nih.gov/20872109
https://pubmed.ncbi.nlm.nih.gov/20872109
Autor:
T M, Handel, E K, Lau
Publikováno v:
Ernst Schering Research Foundation workshop. (45)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b64d90243a1c7e5c321bee8833cf148
https://pubmed.ncbi.nlm.nih.gov/14699797
https://pubmed.ncbi.nlm.nih.gov/14699797
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 7(5)
The synthesis of a 93-residue chemokine, lymphotactin, containing eight sites of O-linked glycosylation, was achieved using the technique of native chemical ligation. A single GalNAc residue was incorporated at each glycosylation site using standard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e81611a74fcc883fdda9d2a9db3529ef
https://pubmed.ncbi.nlm.nih.gov/11303872
https://pubmed.ncbi.nlm.nih.gov/11303872
Autor:
J R, Desjarlais, T M, Handel
Publikováno v:
Journal of molecular biology. 290(1)
We have developed a computational approach for the design and prediction of hydrophobic cores that includes explicit backbone flexibility. The program consists of a two-stage combination of a genetic algorithm and monte carlo sampling using a torsion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::695c327897fb8204da875d1b2376cfc1
https://pubmed.ncbi.nlm.nih.gov/10388574
https://pubmed.ncbi.nlm.nih.gov/10388574
Publikováno v:
Journal of biomolecular NMR. 10(1)
alpha-Lytic protease, a bacterial serine protease of 198 amino acids (19 800 Da), has been used as a model system for studies of catalytic mechanism, structure-function relationships, and more recently for studies of pro region-assisted protein foldi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::caf0901f20488355fd8a8867a4b15559
https://pubmed.ncbi.nlm.nih.gov/9335113
https://pubmed.ncbi.nlm.nih.gov/9335113
Publikováno v:
Protein science : a publication of the Protein Society. 6(1)
E47 is an immunoglobulin enhancer DNA-binding protein that contains a basic region-helix-loop-helix (b/HLH) domain. This structural motif defines a class of transcription factors that are central to the developmental regulation of many tissues. Its f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2cac84ea5528da81cd1afe163370ff02
https://pubmed.ncbi.nlm.nih.gov/9007990
https://pubmed.ncbi.nlm.nih.gov/9007990
Publikováno v:
Macromolecules. 18:1200-1206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a38459f03d624b02ae2a1ec8654fae46
https://doi.org/10.1021/ma00148a027
https://doi.org/10.1021/ma00148a027
Autor:
T. M. Handel, B. C. Johnson, J. N. Cooper, D. A. Farnath, A. M. Carr, S. L. Appleton, W. A. Porter, K. M. Strohmaier, J. G. Bentsen
Publikováno v:
Inorganic Chemistry. 22:3060-3065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a62811d1ac00b2246bd08ea13059f77
https://doi.org/10.1021/ic00163a017
https://doi.org/10.1021/ic00163a017
Autor:
J. S. Tan, T. M. Handel
Publikováno v:
Microdomains in Polymer Solutions ISBN: 9781461292555
The binding behavior of methyl orange to several homopolymers and copolymers containing imidazole and imidazolium salts was investigated as a function of polymer structure and counterion. The polymers were fractionated and characterized by light scat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea66cf33cf012eca36f0b6f15e0740c6
https://doi.org/10.1007/978-1-4613-2123-1_24
https://doi.org/10.1007/978-1-4613-2123-1_24
