Zobrazeno 1 - 7
of 7
pro vyhledávání: '"T. M. H. Liu"'
Publikováno v:
ChemInform. 22
Publikováno v:
The Journal of Organic Chemistry. 56:4929-4932
A efficient process for the commercial preparation of the therapeutically important cholesterol lowering drug synvinolin (2: simvastatin, ZOCOR) from mevinolin(1: lovastatin, MEVACOR) is reported. The synthesis relies upon deactivation of the δ-lact
Publikováno v:
Journal of Medicinal Chemistry. 12:580-583
Publikováno v:
Journal of Heterocyclic Chemistry. 16:1153-1155
Reactions of 2-(4′-fluorophenyl)imidazole (1) and related compounds under various nitrating conditions are discussed. With 90% nitric acid in 20% oleum at −10°, 1 affords 2-(4′fluorophenyl)-4(5)-nitroimidazole (2) in 80% yield. Reaction of 2 w
Publikováno v:
Chemischer Informationsdienst. 11
Publikováno v:
Chemischer Informationsdienst. 10
Publikováno v:
Chemischer Informationsdienst. 16