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pro vyhledávání: '"T. Leahy"'
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Akademický článek
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Autor:
Jim Peterson, Giovanni Di Pasquale, Victoria Makal, Diego Fajardo, Shannon E. Boye, Ryan F. Boyd, Hangning Zhang, Matthew T. Leahy, Shreyasi Choudhury, Kaitlyn R. Calabro, Sandra Afione, Sean Crosson, Russell W. Mellen, Sanford L. Boye, John A. Chiorini, Colin K. Jennings
Publikováno v:
Mol Ther
The majority of inherited retinal diseases (IRDs) are caused by mutations in genes expressed in photoreceptors (PRs). The ideal vector to address these conditions is one that transduces PRs in large areas of retina with the smallest volume/lowest tit
Autor:
Michael P. T. Leahy
The Western world is currently gripped by an obsessive concern for the rights of animals - their uses and abuses. In this book, Leahy argues that this is a movement based upon a series of fundamental misconceptions about the basic nature of animals.T
Publikováno v:
Reproduction-Cambridge-Supplement
Reproduction-Cambridge-Supplement-, Society for Reproduction and Fertility, 2019, 157 (6), pp.R243-R256. ⟨10.1530/REP-18-0627⟩
Reproduction-Cambridge-Supplement-, Society for Reproduction and Fertility, 2019, 157 (6), pp.R243-R256. ⟨10.1530/REP-18-0627⟩
Ejaculation results in the confluence of epididymal spermatozoa with secretions of the accessory sex glands. This interaction is not a prerequisite for fertilisation success, but seminal factors do play a crucial role in prolonging the survival of sp
Autor:
Antonette Bennett, Matthew T. Leahy, Mavis Agbandge-McKenna, Hangning Zhang, Ryan F. Boyd, Sean Crosson, Jim Peterson, Colin K. Jennings, Sanford L. Boye, Shannon E. Boye, Diego Fajardo, Wei Li
Publikováno v:
Journal of Virology. 95
Adeno-associated viruses (AAVs) have recently emerged as the leading vector for retinal gene therapy. However, AAV vectors which are capable of achieving clinically relevant levels of transgene expression and widespread retinal transduction are still
Autor:
Sean M, Crosson, Antonette, Bennett, Diego, Fajardo, James J, Peterson, Hangning, Zhang, Wei, Li, Matthew T, Leahy, Colin K, Jennings, Ryan F, Boyd, Sanford L, Boye, Mavis, Agbandge-McKenna, Shannon E, Boye
Publikováno v:
J Virol
Adeno-associated viruses (AAVs) have recently emerged as the leading vector for retinal gene therapy. However, AAV vectors that are capable of achieving clinically relevant levels of transgene expression and widespread retinal transduction are still
Publikováno v:
Proteomics, 20(12). Wiley-VCH Verlag
Quantitative proteomic studies are contributing greatly to the understanding of the spermatozoon through the provision of detailed information on the proteins spermatozoa acquire and shed in the acquisition of fertility. Extracellular vesicles (EVs)
Publikováno v:
Theriogenology. 118:172-181
Semen cryopreservation is an important tool for artificial breeding, species conservation and human reproductive medicine. However, sublethal freezing damage remains an important limitation of the cryopreservation process, inevitably leading to reduc
Autor:
Xavier Druart, Valérie Labas, Simon P. de Graaf, Kiri Farmer, Ana Paula Teixeira-Gomes, Guillaume Tsikis, Taylor Pini, T. Leahy
Publikováno v:
Cryobiology
Cryobiology, Elsevier, 2018, 82, pp.78-87. ⟨10.1016/j.cryobiol.2018.04.005⟩
Cryobiology, Elsevier, 2018, 82, pp.78-87. ⟨10.1016/j.cryobiol.2018.04.005⟩
International audience; Cryopreservation causes sub-lethal damage which limits the fertility of frozen thawed spermatozoa. Seminal plasma has been investigated as a cryoprotectant, but has yielded inconsistent results due to considerable variation in