Zobrazeno 1 - 10
of 816
pro vyhledávání: '"T. Lamb"'
Autor:
Clayton T. Lamb, Roland Willson, Allyson K. Menzies, Naomi Owens-Beek, Michael Price, Scott McNay, Sarah P. Otto, Mateen Hessami, Jesse N. Popp, Mark Hebblewhite, Adam T. Ford
Publikováno v:
Science. 380:694-696
Recovery targets fall short of culturally meaningful abundance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::608e20b2ec919281e16a129458131750
https://doi.org/10.1126/science.adg9830
https://doi.org/10.1126/science.adg9830
Autor:
Season K. Wyatt-Johnson, Holly N. Kersey, Juan F. Codocedo, Kathy L. Newell, Gary E. Landreth, Bruce T. Lamb, Adrian L. Oblak, Randy R. Brutkiewicz
Publikováno v:
Journal of Neuroinflammation. 20
Background Neuroinflammation is an important feature of Alzheimer’s disease (AD). Understanding which aspects of the immune system are important in AD may lead to new therapeutic approaches. We study the major histocompatibility complex class I-rel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8f7494eedbdb2dcaf10c97cc6e124cd
https://doi.org/10.1186/s12974-023-02761-6
https://doi.org/10.1186/s12974-023-02761-6
Akademický článek
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Publikováno v:
Biogeosciences, Vol 21, Pp 4533-4547 (2024)
To better understand the seasonal variations in environmental conditions regulating dissolved organic matter (DOM) export in agricultural headwater catchments, we combined the monitoring of nitrate, iron, soluble phosphorus, and DOM concentration (as
Externí odkaz:
https://doaj.org/article/495c5ee905b3451d894cb1718ed93018
Autor:
Christel Claes, Whitney E. England, Emma P. Danhash, Sepideh Kiani Shabestari, Amit Jairaman, Jean Paul Chadarevian, Jonathan Hasselmann, Andy P. Tsai, Morgan A. Coburn, Jessica Sanchez, Tau En Lim, Jorge L. S. Hidalgo, Christina Tu, Michael D. Cahalan, Bruce T. Lamb, Gary E. Landreth, Robert C. Spitale, Mathew Blurton‐Jones, Hayk Davtyan
Publikováno v:
Alzheimer's & Dementia. 18:1765-1778
The P522R variant of PLCG2, expressed by microglia, is associated with reduced risk of Alzheimer's disease (AD). Yet, the impact of this protective mutation on microglial responses to AD pathology remains unknown. Chimeric AD and wild-type mice were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::463825c6c305b25a2f0c80da82f03755
https://doi.org/10.1002/alz.12577
https://doi.org/10.1002/alz.12577
Autor:
Miguel Moutinho, Israel Coronel, Andy P. Tsai, Gonzalo Viana Di Prisco, Taylor Pennington, Brady K. Atwood, Shweta S. Puntambekar, Daniel C. Smith, Pablo Martinez, Seonggyun Han, Younghee Lee, Cristian A. Lasagna-Reeves, Bruce T. Lamb, Stephanie J. Bissel, Kwangsik Nho, Gary E. Landreth
Publikováno v:
Genome Medicine. 15
Background TREM2 is a transmembrane receptor expressed by myeloid cells and acts to regulate their immune response. TREM2 governs the response of microglia to amyloid and tau pathologies in the Alzheimer’s disease (AD) brain. TREM2 is also present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::970e39da02545a091cfb94a03486b695
https://doi.org/10.1186/s13073-023-01160-z
https://doi.org/10.1186/s13073-023-01160-z
Autor:
Dominic J. Acri, Yanwen You, Mason D. Tate, Brianne McCord, A. Daniel Sharify, Sutha John, Hande Karahan, Byungwook Kim, Luke C. Dabin, Stéphanie Philtjens, H.R. Sagara Wijeratne, Tyler J. McCray, Daniel C. Smith, Stephanie J. Bissel, Bruce T. Lamb, Cristian A. Lasagna-Reeves, Jungsu Kim
Publikováno v:
bioRxiv
Mouse genetic backgrounds have been shown to modulate amyloid accumulation and propagation of tau aggregates. Previous research into these effects has highlighted the importance of studying the impact of genetic heterogeneity on modeling Alzheimer’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf8a37fbc132fdf0499fb25987e701b
https://doi.org/10.1101/2023.01.28.526029
https://doi.org/10.1101/2023.01.28.526029
Publikováno v:
Proceedings of IMPRS. 5
Objective/Hypothesis: The apoliprotein E epsilon 4 (APOE4) variant is the strongest genetic risk factor for late-onset Alzheimer’s disease (AD) and is associated with accelerated clinical disease. Increasing evidence suggests that the immune system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bf07b81b6100affd15b7730564a37c8
https://doi.org/10.18060/26899
https://doi.org/10.18060/26899
Autor:
Peter Bor-Chian, Lin, Andy Po-Yi, Tsai, Disha, Soni, Audrey, Lee-Gosselin, Miguel, Moutinho, Shweta S, Puntambekar, Gary E, Landreth, Bruce T, Lamb, Adrian L, Oblak
Publikováno v:
Alzheimer's & Dementia.
Inositol polyphosphate-5-phosphatase (INPP5D) is a microglia-enriched lipid phosphatase in the central nervous system. A non-coding variant (rs35349669) in INPP5D increases the risk for Alzheimer's disease (AD), and elevated INPP5D expression is asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37e088464db8e9c5da4fa00ff4a7aa6
https://doi.org/10.1002/alz.12849
https://doi.org/10.1002/alz.12849