Zobrazeno 1 - 10
of 15
pro vyhledávání: '"T. L. Zakharova"'
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 2, Pp 79-82 (2015)
Put forward is an efficient method for manufacturing cholera toxin B-subunit. Its advantages are relative simplicity and economy feasibility, as well as maximum output of the purified B-subunit, absolutely free from toxic A-subunit contaminant. All t
Externí odkaz:
https://doaj.org/article/63fbd44a128e4bd796050e674d2004bd
Autor:
A. K. Nikiforov, M. N. Kireyev, O. V. Gromova, A. V. Komissarov, S. A. Yeriomin, O. A. Volokh, Yu. A. Aleshina, A. V. Gayeva, T. L. Zakharova, V. I. Pavlova
Publikováno v:
Acta Biomedica Scientifica, Vol 0, Iss 5(1), Pp 284-287 (2012)
We evaluated immunochemical, physical and biochemical properties of Vibrio cholerae 569B INABA protective antigenes, derived on industrial and own-developed bioreactors as well as by technology of its concentration by tangential ultrafiltration. We d
Externí odkaz:
https://doaj.org/article/b1b9b3cdfb5c45649dad965ca76841bd
Autor:
T. A. Polunina, N. P. Guseva, M. N. Kireev, T. M. Taranenko, Z. L. Devdariani, S. P. Zadnova, E. M. Kuznetsova, A. V. Stepanov, S. N. Klyueva, T. L. Zakharova
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3(113), Pp 50-53 (2012)
, and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule
Externí odkaz:
https://doaj.org/article/1b330725703b4d678ac7a1c83c7c816d
Autor:
S. N. Klyueva, T. N. Shchukovskaya, T. P. Shmel’Kova, A. L. Kravtsov, S. A. Bugorkova, N. I. Smirnova, O. A. Volokh, T. L. Zakharova, N. I. Belyakova, S. A. Eremin, A. K. Nikiforov
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3(113), Pp 67-70 (2012)
Carried out was immunobiological evaluation of cholera toxin B subunit preparations obtained using different experimental and production methods. It was demonstrated that B subunit preparations were non-toxic for biomodels and did not cause significa
Externí odkaz:
https://doaj.org/article/41d5c63be45a4ac8b06c6aa4bdf53ead
Autor:
S. P. Zadnova, T. A. Polunina, E. M. Kuznetsova, N. P. Guseva, Z. L. Devdariani, T. M. Taranenko, S. N. Klyueva, M. N. Kireev, A. V. Stepanov, T. L. Zakharova
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 3(113), Pp 50-53 (2012)
and degraded polysaccharide (PS) are easily soluble in water and in 0,9 % NaCl solution. They are homogenous and characterized by an adequate degree of purity. Aside from that, it is demonstrated that potentially PS is the most productive molecule fr
Publikováno v:
Проблемы особо опасных инфекций, Vol 0, Iss 2(100), Pp 68-71 (2009)
Proposed is the method for simultaneous isolation and purification of three cholera vibrio key pathogenicity factors (cholera toxin, toxin-co-regulated adhesion pili, O1 antigen Ogawa or Inaba), which are main protective antigens, from previously con
Autor:
D V, Utkin, N A, Osina, A N, Spitsin, M N, Kireev, O V, Gromova, T L, Zakharova, E V, Naidenova, V E, Kuklev
Publikováno v:
Klinicheskaia laboratornaia diagnostika. 60(2)
The full-scaled agglutinating immunoassay is commonly applied to detect content of antibodies to cholera agent Vibrio cholerae human in blood serum under application of serological diagnostic. The time of analysis implementation amounts to 18 hours.
Autor:
N I, Smirnova, L F, Livanova, G V, Chekhovskaia, G A, Eroshenko, Iu V, Lazovskiĭ, T L, Zakharova
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (3)
To find out stable and effective producers of major protective antigens intended for use as components of cholera chemical vaccine against V. cholerae strains of serogroups O and O139, the comparative analysis of the production of cholera toxin, toxi
Autor:
M N, Dzhaparidze, A V, Naumov, O V, Gromova, A K, Adamov, Iu Iu, Eliseev, O M, Kosmoenko, I A, Kuz'michenko, V N, Kopyrzov, V I, Zavorotnykh, T L, Zakharova, G V, Chekhovskaia
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (2)
Conditions for the submerged cultivation of a strain of V. cholerae O139, were worked out. These conditions ensured a high yield of biomass, soluble O-antigen and exoenzymes (proteinase, phospholipase A) into the culture medium, which exceeded their
Autor:
M N, Dzhaparidze, A V, Naumov, G P, Nikitina, M V, Meleshchenko, G V, Dobrova, V I, Zavorotnykh, V P, Gracheva, T L, Zakharova
Publikováno v:
Zhurnal mikrobiologii, epidemiologii i immunobiologii. (4)
The material on the development of chemical vaccine, prepared from two newly formed strains (KM-76 Inaba and KM-68 Ogawa) and intended for oral administration, is presented. The conditions for the submerged cultivation of these strains have been esta