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pro vyhledávání: '"T. Kuppusamy"'
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Akademický článek
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Akademický článek
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Autor:
Hannele Ruohola-Baker, Henrik Sperber, Zsuzsa Agoston, Randall T. Moon, Amy Ferreccio, Yalan Xing, Julie Mathieu, Wenyu Zhou, Kavitha T. Kuppusamy
Publikováno v:
Cell Stem Cell. 14:592-605
SummaryPluripotent stem cells have distinct metabolic requirements, and reprogramming cells to pluripotency requires a shift from oxidative to glycolytic metabolism. Here, we show that this shift occurs early during reprogramming of human cells and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a640c91e334e65dd168bed01cecb72
https://doi.org/10.1016/j.stem.2014.02.012
https://doi.org/10.1016/j.stem.2014.02.012
Publikováno v:
Current Molecular Medicine. 13:757-764
There are currently 1527 known microRNAs (miRNAs) in human, each of which may regulate hundreds or thousands of target genes. miRNA expression levels vary between cell types; for example, miR- 302 and miR-290 families are highly enriched in embryonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116f2c7acacd6a7f9fa1085bbe303d4e
https://doi.org/10.2174/1566524011313050007
https://doi.org/10.2174/1566524011313050007
Autor:
Daniel C. Jones, Nathan J. Palpant, Kavitha T. Kuppusamy, Xinxia Peng, Walter L. Ruzzo, Hannele Ruohola-Baker, Charles E. Murry
While RNA-Seq has enabled great progress towards the goal of wide-scale isoform-level mRNA quantification, short reads have limitations when resolving complex or similar sets of isoforms. As a result, estimates of isoform abundance carry far more unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce86535a3896f908faae2bbd7773f823
Publikováno v:
Proceedings of the National Academy of Sciences. 106:8073-8076
The simple structure of Arabidopsis roots provides an excellent model system to study epidermal cell fate specification. Epidermal cells in contact with 2 underlying cortical cells differentiate into hair cells (H cells; trichoblasts), whereas cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a04cc8ae8e02f8f8aad45ca86d3491
https://doi.org/10.1073/pnas.0811633106
https://doi.org/10.1073/pnas.0811633106
Publikováno v:
Plant Molecular Biology. 69:375-381
Recent studies suggest that hormones act through a web of interacting responses rather than through isolated linear pathways. This signal integration architecture may be one mechanism for increasing the specificity of outcomes in different cellular c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da36013a401a470c1231f14f2b68b5a6
https://doi.org/10.1007/s11103-008-9389-2
https://doi.org/10.1007/s11103-008-9389-2
Autor:
Hannele Ruohola-Baker, Lil Pabon, Charles E. Murry, Nathan J. Sniadecki, Karin A. Fischer, Walter L. Ruzzo, Wei-Zhong Zhu, Anup Madan, Xiulan Yang, Marita L. Rodriguez, Kavitha T. Kuppusamy, Nathaniel L. Tulloch, Michael A. Laflamme, Henrik Sperber, Daniel C. Jones
Publikováno v:
Proceedings of the National Academy of Sciences. 112
In metazoans, transition from fetal to adult heart is accompanied by a switch in energy metabolism-glycolysis to fatty acid oxidation. The molecular factors regulating this metabolic switch remain largely unexplored. We first demonstrate that the mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aec77136ba4896cf69b026066ff0a41
https://doi.org/10.1073/pnas.1424042112
https://doi.org/10.1073/pnas.1424042112
Autor:
T. Kuppusamy
Publikováno v:
International Journal for Numerical and Analytical Methods in Geomechanics. 17:457-469
Aquifer contamination by organic chemicals in subsurface flow through soils due to leaking underground storage tanks filled with organic fluids is an important groundwater pollution problem. The problem involves transport of a chemical pollutant thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c624d05611aa4e7276f87420b583495f
https://doi.org/10.1002/nag.1610170703
https://doi.org/10.1002/nag.1610170703