Zobrazeno 1 - 10
of 170
pro vyhledávání: '"T. Komata"'
Autor:
Naoyuki Tsuchiya, S. Yamamoto, M. Matsushita, Katsushi Tokunaga, T. Komata, Jun Ohashi, Yoko Hatta
Publikováno v:
Annals of Human Genetics. 65:197-206
In case-control studies of complex disease genes, allele frequencies or allele positivities at candidate loci or markers are compared between cases and controls. Although 2 x 2 contingency tables based on allele frequency and allele positivity are ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88fd6ad096ac90f85bb5cb76f0533d2
https://doi.org/10.1017/s000348000100851x
https://doi.org/10.1017/s000348000100851x
Publikováno v:
Annals of Human Genetics. 65:197-206
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5972a21996463bfa5b755f0b992e3e83
https://doi.org/10.1046/j.1469-1809.2001.6520197.x
https://doi.org/10.1046/j.1469-1809.2001.6520197.x
Autor:
K. Zama, Naoyuki Tsuchiya, T. Komata, Takanori Oka, Kunio Matsuta, Akio Yamane, Takeo Juji, M. Matsushita, Katsushi Tokunaga, Michiko Shiota
Publikováno v:
Tissue Antigens. 54:578-584
CTLA-4 is considered to be one of the attractive candidates for the susceptibility genes to rheumatic diseases. In the present study, the association of CTLA-4 polymorphism with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) was exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71b80981e4c4a728c904a498e53592bc
https://doi.org/10.1034/j.1399-0039.1999.540607.x
https://doi.org/10.1034/j.1399-0039.1999.540607.x
Publikováno v:
Tissue Antigens. 53:527-533
Multiple genetic as well as environmental factors are considered to be involved in the development of systemic lupus erythematosus (SLE). A number of previous studies have suggested a possible role for tumor necrosis factor (TNF) in the pathogenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34791c8264807847b84160a406eaa668
https://doi.org/10.1034/j.1399-0039.1999.530602.x
https://doi.org/10.1034/j.1399-0039.1999.530602.x
Autor:
Naoyuki Tsuchiya, T. Komata, Yoko Hatta, Hiroshi Mitsui, M. Matsushita, Katsushi Tokunaga, Atsuko Ogawa
Publikováno v:
Japanese Journal of Rheumatology. 9:55-64
Although the crucial role of HLA-B27 for the development of seronegative spondy-loarthropathies (SpA) has been established, family and twin studies indicated the presence of additional genetic factors. To determine whether HLA-DRB1 gene acts as an ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349c74cf9c5d49657ed6f97f96662e8f
https://doi.org/10.1007/bf03041259
https://doi.org/10.1007/bf03041259
Publikováno v:
Anticancer research. 21(3B)
Gene transfer vectors will dramatically increase the safety and effectiveness of cancer gene therapy, if they could restrict expression of the therapeutic products to the target tumors. To realize such a tumor-targeting system, telomerase is one of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d05ddf73a1fb2ac3b451b12a5723bdf
https://pubmed.ncbi.nlm.nih.gov/11497281
https://pubmed.ncbi.nlm.nih.gov/11497281
Autor:
T, Komata, Y, Kondo, T, Kanzawa, S, Hirohata, S, Koga, H, Sumiyoshi, S M, Srinivasula, B P, Barna, I M, Germano, M, Takakura, M, Inoue, E S, Alnemri, J W, Shay, S, Kyo, S, Kondo
Publikováno v:
Cancer research. 61(15)
Because the apoptotic pathway is often disrupted in tumor cells, its genetic restoration is a very attractive approach for the treatment of tumors. To treat malignant gliomas with this approach, it would be preferred to restrict induction of apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::762bc613f0a49039a2ad98dba06e771e
https://pubmed.ncbi.nlm.nih.gov/11479218
https://pubmed.ncbi.nlm.nih.gov/11479218
Autor:
Naoyuki Tsuchiya, A Kawasaki, Betty P. Tsao, T. Komata, Jennifer M. Grossman, Katsushi Tokunaga
Publikováno v:
Genes and immunity. 2(6)
A number of studies reported associations of HLA-DRB1, TNFalpha (TNF) promoter and TNF receptor II (TNFR2, TNFRSF1B) polymorphisms with systemic lupus erythematosus (SLE), however, the results have often been inconsistent. Such lack of consistency co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2316321dd151b6b107d74a355bf2164b
https://pubmed.ncbi.nlm.nih.gov/11607787
https://pubmed.ncbi.nlm.nih.gov/11607787
Publikováno v:
Gene therapy. 7(24)
Malignant gliomas of astrocytic origin have commonly expressed several features such as alterations in the tumor-suppressor gene p53 or p16 or the acquisition of telomerase activity, which are distinctive from astrocytes. Therefore, restoration of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786c00e9b1af02866faac47793bfef5f
https://pubmed.ncbi.nlm.nih.gov/11223987
https://pubmed.ncbi.nlm.nih.gov/11223987
Publikováno v:
Genes and immunity. 1(8)
We recently reported the association of the allele coding for Arg at the position 196 (196R: nucleotide [nt] 587G) of tumor necrosis factor receptor 2 (TNFR2, TNF-R75) with systemic lupus erythematosus (SLE) in Japanese. In the present study, we comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ac2f0393275ef643ffe5b29a1da2fc
https://pubmed.ncbi.nlm.nih.gov/11197692
https://pubmed.ncbi.nlm.nih.gov/11197692