Zobrazeno 1 - 10
of 218
pro vyhledávání: '"T. Kealey"'
Publikováno v:
Metabolic Engineering Communications, Vol 13, Iss , Pp e00172- (2021)
Lichen-forming fungi produce a variety of secondary metabolites including bioactive polyketides. Advances in DNA and RNA sequencing have led to a growing database of new lichen gene clusters encoding polyketide synthases (PKS) and associated ancillar
Externí odkaz:
https://doaj.org/article/f523e2ef63ec47b282b4dfa8338a6bba
Autor:
Stephen C Waring, György J. Simon, Roshan Tourani, Rabindra Tambyraja, Bryan Jarabek, Karyn D. Baum, Michael G. Usher, Burke T Kealey, Deepti Pandita, Craig Strauss, Christopher J. Tignanelli, Niall A M Klyn
Publikováno v:
JAMIA Open
Objective Ensuring an efficient response to COVID-19 requires a degree of inter-system coordination and capacity management coupled with an accurate assessment of hospital utilization including length of stay (LOS). We aimed to establish optimal prac
Akademický článek
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Publikováno v:
Review of Pacific Basin Financial Markets and Policies. 24:2150022
Directors’ monitoring and advising activities as agents were supposed to increase after the Dodd-Frank Act in 2010. The Dodd-Frank Act significantly increases the pressure on the board of directors to be more effective agents of the stockholders ev
Akademický článek
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Publikováno v:
Process Biochemistry. 46:1703-1710
Successful elucidation and optimization of the biosynthetic pathways for isoprenoids can lead to an array of natural products with a wide range of properties, including biofuels, pharmaceuticals, flavors, and fragrances. In order to maximize the pote
Publikováno v:
Analytical Biochemistry. 394:75-80
A sensitive fluorescent assay was developed to measure the extent of phosphopantetheinylation of polyketide synthase (PKS) acyl carrier protein (ACP) domains in polyketide production strains. The in vitro assay measures PKS fluorescence after transfe
Autor:
John C. Vederas, Jin W. Choi, Suzanne M. Ma, Vijayalakshmi A. Moorthie, K. K. Michael Lee, James T. Kealey, Jesse W.-H. Li, Hui Zhou, Xinkai Xie, Yi Tang, Nancy A. Da Silva
Publikováno v:
Science. 326:589-592
Dissecting Megaenzyme Mechanisms Filamentous fungi contain a class of multidomain enzymes, the highly-reducing iterative polyketide synthases (HR-IPKSs), which produce important natural products such as the cholesterol-lowering drug lovastatin. To pr
Publikováno v:
Applied and Environmental Microbiology. 74:5121-5129
Gene clusters for biosynthesis of the fungal polyketides hypothemycin and radicicol from Hypomyces subiculosus and Pochonia chlamydosporia , respectively, were sequenced. Both clusters encode a reducing polyketide synthase (PKS) and a nonreducing PKS
Publikováno v:
AUDITING: A Journal of Practice & Theory. 26:95-116
This study tests whether prior auditor-client tenure is associated with the audit fees paid to the successor auditor. In the past, studying the association between tenure with the prior auditor and fees charged by the successor was problematic becaus