Zobrazeno 1 - 10
of 372
pro vyhledávání: '"T. Kalland"'
Autor:
T. Kalland, R. Holmdahl
Publikováno v:
Toxicity of Hormones in Perinatal Life ISBN: 9780429283116
Toxicity of Hormones in Perinatal Life
Toxicity of Hormones in Perinatal Life
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4c238c3d1e54b14b68fc9459ce701a
https://doi.org/10.1201/9780429283116-8
https://doi.org/10.1201/9780429283116-8
Publikováno v:
Infection and Immunity. 65:5118-5124
The bacterial superantigen staphylococcal enterotoxin A (SEA) binds with high affinity to major histocompatibility complex (MHC) class II molecules and subsequently activates T cells bearing particular T-cell receptor (TCR) Vbeta chains. Structural a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6b713ad5d8a5015f90b69b05d1ae1f
https://doi.org/10.1128/iai.65.12.5118-5124.1997
https://doi.org/10.1128/iai.65.12.5118-5124.1997
Publikováno v:
The Journal of Immunology. 158:4245-4251
In this report, we show that despite an overall amino acid residue identity of more than 80% between the staphylococcal enterotoxins (SE) A and E, these proteins markedly differ in their absolute requirement for the MHC class II during T cell activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f4dc1d18aebb1f805a3f5dd13727d3f
https://doi.org/10.4049/jimmunol.158.9.4245
https://doi.org/10.4049/jimmunol.158.9.4245
Autor:
P O Gunnarsson, B Persson, Bruce J. Giantonio, L Vitek, B Shannon, R Persson, Y Guedez, M Kotb, C. McAleer, T Kalland, M Dohlsten, Duane W. Newton, Louis M. Weiner, R K Alpaugh, Josephine Schultz
Publikováno v:
Journal of Clinical Oncology. 15:1994-2007
PURPOSE To establish the maximum-tolerated dose (MTD) and define the toxicities of a single-dose infusion of PNU-214565, a recombinant Escherichia coli-derived fusion protein of Staphylococcal enterotoxin A (SEA) and the Fab-fragment of the C242 mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f851847f137044e3a6bd7982562f0eb3
https://doi.org/10.1200/jco.1997.15.5.1994
https://doi.org/10.1200/jco.1997.15.5.1994
Publikováno v:
The Journal of Immunology. 158:637-642
This study compares the ability of LFA-3 (CD58) and B7-1 (CD80) ligands to provide costimulatory signals for superantigen (SAg)-stimulated CD8+ and CD4+ T cells. We show that B7-1 and LFA-3 costimulation activate CD8+ T cells to proliferation, cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9b2393cea751079ee7d1d3a7517bd9
https://doi.org/10.4049/jimmunol.158.2.637
https://doi.org/10.4049/jimmunol.158.2.637
Publikováno v:
The Journal of Immunology. 158:180-186
Injection of the superantigen staphylococcal enterotoxin A (SEA) to mice rapidly elicits production of the Th1-related pro-inflammatory cytokines IL-2, TNF, and IFN-gamma, while repeated SEA challenges transduce a hyporesponsive state characterized b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f0358c6ce565376fdc08243ecd7419
https://doi.org/10.4049/jimmunol.158.1.180
https://doi.org/10.4049/jimmunol.158.1.180
Publikováno v:
The Journal of Immunology. 157:3988-3994
C-terminal residues of staphylococcal enterotoxin A (SEA), including H187, D225, and D227, are involved in moderate affinity binding to MHC class II beta-chain, whereas N-terminal residues, including F47, are involved in low affinity binding to MHC c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fce3361700b66838bac89924cf636cf5
https://doi.org/10.4049/jimmunol.157.9.3988
https://doi.org/10.4049/jimmunol.157.9.3988
Regulation of superantigen-induced T cell activation in the absence and the presence of MHC class II
Publikováno v:
The Journal of Immunology. 157:2857-2863
To study MHC class II-dependent and -independent SAg2 activation and the relative importance of CD80/CD28 costimulation, staphylococcal enterotoxin A (SEA) was presented to T cells as a fusion protein containing the Fab fragment of an mAb directed ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eac6ca02f837f9d9b427ecba8541241
https://doi.org/10.4049/jimmunol.157.7.2857
https://doi.org/10.4049/jimmunol.157.7.2857
Publikováno v:
The Journal of Immunology. 155:1132-1140
We have earlier shown that stimulation of human CD4+ T cells with SEA presented on Chinese hamster ovary (CHO)-DR transfectants coexpressing either B7 or LFA-3 resulted in distinct cytokine profiles. We now demonstrate that B7, but not LFA-3, strongl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::189a9914b6e3c76c38815bfb4441d0bb
https://doi.org/10.4049/jimmunol.155.3.1132
https://doi.org/10.4049/jimmunol.155.3.1132
Autor:
Dimitrios Karussis, Haim Ovadia, Oded Abramsky, A. Ben-Nun, D. Lehmann, T. Kalland, Shimon Slavin, U. Vourka-Karussis, R. Mizrachi-Koll
Publikováno v:
Annals of Neurology. 34:654-660
Linomide (LS-2616, quinoline-3-carboxamide) is a synthetic immunomodulator that stimulates natural killer cell activity and activates several lymphocytic subpopulations in experimental animals and humans. In this study we determined the effect of ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e66cb7b62f0cabfb602164fdf366890
https://doi.org/10.1002/ana.410340506
https://doi.org/10.1002/ana.410340506