Zobrazeno 1 - 10
of 48
pro vyhledávání: '"T. K. Venkatachalam"'
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract A detailed NMR investigation of the chemical shifts of hydrogen and carbon atoms associated with the structure of the naturally occurring alkaloid colchicine was conducted using high field NMR. Initially, the experimental chemical shifts for
Externí odkaz:
https://doaj.org/article/d857b1422a124fbba8eb18831bde812e
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 152
The reaction of [
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 131
[
Publikováno v:
Protein Science. 8:2399-2405
Pokeweed antiviral protein (PAP) is a ribosome-inactivating protein (RIP), which enzymatically removes a single adenine base from a conserved, surface exposed loop sequence of ribosomal rRNA. We now present unprecedented experimental evidence that PA
Publikováno v:
Magnetic resonance in chemistry : MRC. 54(4)
A comparative study of experimental and calculated NMR chemical shifts of six compounds comprising 2-amino and 2-hydroxy phenyl benzoxazoles/benzothiazoles/benzimidazoles in four solvents is reported. The benzimidazoles showed interesting spectral ch
Publikováno v:
Synthetic Communications. 34:1489-1497
Polyhydroxylated stilbene analogs of piceatannol are shown to possess protein‐tyrosine kinase (PTK) inhibitory activity. We have developed a novel approach to introduce an amide moiety into the structure of piceatannol. The amido substituted stilbe
Autor:
F. M. Uckun, T. K. Venkatachalam
Publikováno v:
Synthetic Communications. 34:2451-2461
The regiospecific synthesis of 5‐halothiophenethylamines and halo‐substituted phenylethyl thioureas was accomplished with an overall yield of 45–60%. Condensation of t‐boc protected 2‐thiophenethylamine with N‐halo succinamide in dimethyl
Autor:
T. K. Venkatachalam, F. M. Uckun M.D.
Publikováno v:
Synthetic Communications. 34:2463-2472
Synthesis of β‐fluorophenethylamines was accomplished in three steps with an overall yield of 50%. Condensation of β‐fluorophenethylamine hydrochloride with thiocarbonylimidazole derivative derived from halopyridyl amines in dimethylformamide f
Publikováno v:
Synthetic Communications. 33:1185-1193
We developed a novel approach to introduce a carbohydrate moiety into the structure of thiourea compounds targeting the NNI binding pocket of the HIV-1 reverse transcriptase. The described method involves the synthesis of an amino-substituted carbohy
Publikováno v:
Magnetic resonance in chemistry : MRC. 53(6)
The 2-(benzo[d]thiazole-2'-yl)-N-alkylanilines have previously revealed the presence of a strong intramolecular hydrogen bond. This in turn gives rise to a more complicated multiplet for the protons attached to the carbon adjacent to the amino group.