Zobrazeno 1 - 10
of 34
pro vyhledávání: '"T. J. Sayers"'
Publikováno v:
The Journal of Immunology. 153:333-342
Isolated murine splenic NK cells and the cultured murine endothelioma cell line, eEND2, were used to study the effects of cytokines on NK cell/endothelial cell adhesion. Treatment of eEND2 cells with TNF-alpha induced a marked increase (four- to seve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16cd2527b462deee548a5bb9320f1b1f
https://doi.org/10.4049/jimmunol.153.1.333
https://doi.org/10.4049/jimmunol.153.1.333
Publikováno v:
The Journal of Immunology. 150:3634-3642
Human PBL (huPBL) were activated with anti-CD3 mAb in vitro and then were transferred into mice with severe combined immune deficiency (SCID) to determine the effect of activation on engraftment and to determine if the engrafted human cells could pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d088ac09c504db44e7a598decd624f8
https://doi.org/10.4049/jimmunol.150.8.3634
https://doi.org/10.4049/jimmunol.150.8.3634
Autor:
T Wiltrout, J C Powers, Mark J. Smyth, C M Kam, T J Sayers, R Sowder, H A Young, Joseph A. Trapani, L E Henderson, K S Ottaway
Publikováno v:
Scopus-Elsevier
We have purified a 30-kDa serine protease (designated RNK-Met-1) from the granules of the rat large granular lymphocyte leukemia cell line (RNK-16) that hydrolytically cleaves model peptide substrates after methionine, leucine, and norleucine (Met-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19132ec0c09ac8ff75a0f47d0e63304a
https://doi.org/10.1016/s0021-9258(18)35783-1
https://doi.org/10.1016/s0021-9258(18)35783-1
Publikováno v:
Apoptosis : an international journal on programmed cell death. 8(2)
Lewis lung carcinoma (3LL) cells were constitutively resistant to Fas-mediated apoptosis, but overexpression of Fas on 3LL cells allowed Fas-mediated apoptosis after crosslinking with agonist anti-Fas antibody (Jo2) in vitro. Surprisingly, Fas-overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd84601ce62cc5da0bcf05f8cf24cf60
https://pubmed.ncbi.nlm.nih.gov/12766475
https://pubmed.ncbi.nlm.nih.gov/12766475
Publikováno v:
Journal of leukocyte biology. 70(1)
Cytotoxic lymphocytes largely comprise CD8(+) cytotoxic T cells and natural killer cells and form the major defense of higher organisms against virus-infected and transformed cells. A key function of cytotoxic lymphocytes is to detect and eliminate p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94f9d2c0425fff88ef54efc6f5764f50
https://pubmed.ncbi.nlm.nih.gov/11435481
https://pubmed.ncbi.nlm.nih.gov/11435481
Autor:
T J, Sayers, A D, Brooks, J M, Ward, T, Hoshino, W E, Bere, G W, Wiegand, J M, Kelly, M J, Smyth, J M, Kelley
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 166(2)
We have analyzed the expression of human granzyme M (Gzm M) in various human leukocyte subsets using the specific mAb 4H10. Using FACS and Western blotting analysis we compared the expression of Gzm M with that of other granzymes (Gzm A and Gzm B) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3948a1977fa68f8ada4680ae36e402fd
https://pubmed.ncbi.nlm.nih.gov/11145648
https://pubmed.ncbi.nlm.nih.gov/11145648
Publikováno v:
Journal of leukocyte biology. 68(1)
Activated T cells lyse the murine renal cancer Renca. We have examined the mechanism of tumor cell lysis with the use of T cells derived from C57BL/6, BALB/c, B6.gld, and B6.Pfp-/- mice. C57BL/6 and BALB/c T cells can lyse Renca cells through the use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e1a57cb10cf6bee64c954cc87978f0e3
https://pubmed.ncbi.nlm.nih.gov/10914493
https://pubmed.ncbi.nlm.nih.gov/10914493
Autor:
T J, Sayers, A D, Brooks, J K, Lee, R G, Fenton, K L, Komschlies, J M, Wigginton, R, Winkler-Pickett, R H, Wiltrout
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(8)
Mice bearing the experimental murine renal cancer Renca can be successfully treated with some forms of immunotherapy. In the present study, we have investigated the molecular pathways used by NK and T cells to lyse Renca cells. Renca cells normally e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7c4117ad1fbbf1b691bb59d61510e8b
https://pubmed.ncbi.nlm.nih.gov/9780164
https://pubmed.ncbi.nlm.nih.gov/9780164
Publikováno v:
Cancer research. 58(15)
The ras oncogene plays an important role in the multistep progression to cancer by activation of signal transduction pathways that contribute to aberrant growth regulation. Although many of these effects are cell autonomous, the ras oncogene also reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::26b6b7ed18d028ccda8b4eabe40227ef
https://pubmed.ncbi.nlm.nih.gov/9699671
https://pubmed.ncbi.nlm.nih.gov/9699671
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(8)
Chemokines have been shown to play an important role in both the adhesion and migration of numerous leukocytic cell types, including granulocytes, monocytes, mast cells, and T lymphocytes. However, the biologic effects of chemokines on NK cells remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::006ee3d5a8d991816ae424b046644a85
https://pubmed.ncbi.nlm.nih.gov/7561094
https://pubmed.ncbi.nlm.nih.gov/7561094