Výsledky vyhledávání - "T. J. SIMPSON"

First in vitro directed biosynthesis of new compounds by a minimal type II polyketide synthase: evidence for the mechanism of chain length determination

Autor: T P, Nicholson, C, Winfield, J, Westcott, J, Crosby, T J, Simpson, R J, Cox

Publikováno v: Chemical communications (Cambridge, England). (6)

The minimal actinorhodin polyketide synthase bearing two point mutations (KSbeta Q161A, ACP C17S) was chemically modified to carry novel C4 to C8 starter units on the ACP: on incubation with an excess of malonyl CoA new 16-carbon polyketides are made

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6497f6d77c58076254d72a84fa365cc9
https://pubmed.ncbi.nlm.nih.gov/12703773

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Navigating turbulent and uncharted waters

Autor: T J, Simpson

Publikováno v: Cambridge quarterly of healthcare ethics : CQ : the international journal of healthcare ethics committees. 8(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::caa60b4327231641f2092c4902ffcb6b
https://pubmed.ncbi.nlm.nih.gov/10513310

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Characterization of a monoclonal antibody to cis-urocanic acid: detection of cis-urocanic acid in the serum of irradiated mice by immunoassay

Autor: A M, Moodycliffe, M, Norval, I, Kimber, T J, Simpson

Publikováno v: Immunology. 79(4)

Cis-urocanic acid (cis-UCA), which is formed from the naturally occurring trans-isomer on ultraviolet (UV) irradiation, has been suggested as a photoreceptor for and mediator of the suppressive effects of UV irradiation on systemic immune responses.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3fe81c875bcfafd25d8d285666d84cd3
https://pubmed.ncbi.nlm.nih.gov/8406594

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The role of histamine-like receptors in immunosuppression of delayed hypersensitivity induced by cis-urocanic acid

Autor: J W, Gilmour, M, Norval, T J, Simpson, K, Neuvonen, P, Pasanen

Publikováno v: Photodermatology, photoimmunologyphotomedicine. 9(6)

The cis-isomer of urocanic acid (UCA) has been shown previously to mimic the effect of ultraviolet B (UVB) irradiation in suppressing delayed hypersensitivity (DH) responses to virus in a murine model of herpes simplex virus (HSV) infection. Cimetidi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::182ef8f324bd8299f9e9f1db311ef4b1
https://pubmed.ncbi.nlm.nih.gov/1343226

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The effect of histamine receptor antagonists on immunosuppression induced by the cis-isomer of urocanic acid

Autor: M, Norval, J W, Gilmour, T J, Simpson

Publikováno v: Photodermatology, photoimmunologyphotomedicine. 7(6)

Urocanic acid (UCA) is found in the stratum corneum predominantly as the trans-isomer; on ultraviolet B (UVB) irradiation, isomerization to the cis-isomer occurs. Cis-UCA has been shown to mimic the consequences of UVB irradiation in generating trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1329425740568614893e1303d17bb82
https://pubmed.ncbi.nlm.nih.gov/1983293

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What Spatial Frames of Reference are Used to Guide Off-Axis Aiming?

Autor: T J Simpson, L A Skinner, P T Sowden, I R L Davies, S K Boyles

Publikováno v: Perception. 26:364-364

What spatial frames of reference are used to guide body centred actions such as pointing and aiming? Do observers learn to use body-scaled frames of reference with specific points of origin (eg hip vs shoulder)? Do they extrapolate general informatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc539365235ac165adf79c93e314fd94
https://doi.org/10.1068/v970252

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