Výsledky vyhledávání - "T. J. Oglesby"

Akademický článek

Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay.

Autor: S.-W. Cho¹, T. J. Oglesby¹, B.-L. Hsi², E. M. Adams¹, J. P. Atkinson¹

Publikováno v: Clinical & Experimental Immunology. Feb1991, Vol. 83 Issue 2, p257-261. 5p.

Zobrazit plný text záznamu

Substituted isocoumarins as inhibitors of complement serine proteases

Autor: C M Kam, T J Oglesby, M K Pangburn, J E Volanakis, J C Powers

Publikováno v: The Journal of Immunology. 149:163-168

Inhibition of complement proteins D, B, C2, C1s, C1r, I, and the catalytic fragments Bb and C2a by substituted isocoumarins was investigated. 3,4-Dichloroisocoumarin, a general serine protease inhibitor, inhibited factor D, C1r, and C1s moderately wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fa86fe8932f069fc8efa23db9ab0574
https://doi.org/10.4049/jimmunol.149.1.163

Zobrazit plný text záznamu

Membrane cofactor protein (CD46) protects cells from complement-mediated attack by an intrinsic mechanism

Autor: John P. Atkinson, T. J. Oglesby, D. J. G. White, Christopher J. Allen, M. K. Liszewski

Publikováno v: The Journal of Experimental Medicine

The cleavage of C3 is a critical step for complement (C) activation in the classical and alternative pathways. This reaction is controlled by the regulators of C activation protein family. Membrane cofactor protein (MCP) is a cofactor for the factor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b25774d2fe90b62541b69d7ee23ba43
https://doi.org/10.1084/jem.175.6.1547

Zobrazit plný text záznamu

SEPARATION OF SELF FROM NON-SELF IN THE COMPLEMENT SYSTEM: A ROLE FOR MEMBRANE COFACTOR PROTEIN AND DECAY ACCELERATING FACTOR

Autor: E A Adams, M K Liszewski, D White, John P. Atkinson, T J Oglesby

Publikováno v: Clinical and Experimental Immunology. 86:27-30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27113e15e9879fef67e925baa79c0b0a
https://doi.org/10.1111/j.1365-2249.1991.tb06203.x

Zobrazit plný text záznamu

Human complement regulator expression by the normal female reproductive tract

Autor: T J, Oglesby, J E, Longwith, P C, Huettner

Publikováno v: The Anatomical record. 246(1)

The membrane-associated proteins that regulate human complement activation are ubiquitously expressed and function cooperatively to protect cells from autologous complement damage. For classical and alternative pathways, the primary regulators at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dad2c7bf7589f05802050bd5896d8d38
https://pubmed.ncbi.nlm.nih.gov/8876826

Zobrazit plný text záznamu

Expression of decay-accelerating factor (CD55) of the complement system on human spermatozoa

Autor: F, Cervoni, T J, Oglesby, P, Fénichel, G, Dohr, B, Rossi, J P, Atkinson, B L, Hsi

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 151(2)

Human spermatozoa were analyzed for their expression of decay-accelerating factor (DAF, CD55), a glycolipid-anchored regulatory protein of the C casade. Morphologic data showed that DAF was localized at the acrosomal region of the sperm head. Analysi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8016852d9b6e595959a1825f1f62e6cf
https://pubmed.ncbi.nlm.nih.gov/7687624

Zobrazit plný text záznamu

Characterization of three monoclonal antibodies to membrane co-factor protein (MCP) of the complement system and quantification of MCP by radioassay

Autor: B. L. Hsi, E. M. Adams, John P. Atkinson, S.-W. Cho, T J Oglesby

SUMMARY MCP is a widely distributed regulatory glycoprotein of the complement system which binds C3b and C4b and has factor I-dependent co-factor activity. Monoclonal antibodies raised to lymphocytes (E4.3), chorionic microvilli (GB24) and an embryon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad890ea28ca7bbb54b78a444e0a4dd1
https://europepmc.org/articles/PMC1535256/

Zobrazit plný text záznamu

Evidence for a C4b binding site on the C2b domain of C2

Autor: T J Oglesby, M A Accavitti, J E Volanakis

Publikováno v: The Journal of Immunology. 141:926-931

We raised murine mAb against human C protein C2. The representative mAb 3A3.3 (IgG1 kappa) recognized an epitope on the C2b domain of C2, as determined by binding and inhibition of binding radioassays. The hemolytic activity of purified human C2 and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb1f28217854b8799d7fa6f64ed3b22e
https://doi.org/10.4049/jimmunol.141.3.926

Zobrazit plný text záznamu

Lysis of sensitized sheep erythrocytes in human sera deficient in the second component of complement

Autor: K L, Knutzen Steuer, L B, Sloan, T J, Oglesby, T C, Farries, M W, Nickells, P, Densen, J B, Harley, J P, Atkinson

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 143(7)

Analysis of C-dependent lysis of sensitized SRBC by C2-deficient sera (C2D) led to the characterization of a C2 bypass pathway. Lysis in the total hemolytic C assay by C2D sera was Ca2+-dependent and required a high concentration of hemolysin to sens

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::64d62f7da315988ee81e90042bd12b3f
https://pubmed.ncbi.nlm.nih.gov/2506280

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání