Zobrazeno 1 - 10
of 72
pro vyhledávání: '"T. J. MacVittie"'
Autor:
A M Farese, T J MacVittie
Publikováno v:
Drugs of today (Barcelona, Spain : 1998). 51(9)
The U.S. Food and Drug Administration (FDA) recently approved Neupogen(®) (filgrastim) for the treatment of patients with radiation-induced myelosuppression following a radiological/nuclear incident. It is the first medical countermeasure currently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9a39aef4f396d0c0148f126eab76c0
https://pubmed.ncbi.nlm.nih.gov/26488033
https://pubmed.ncbi.nlm.nih.gov/26488033
Publikováno v:
Blood. 84:2515-2522
Using a nonhuman-primate model of radiation-induced bone marrow aplasia, we examined whether the single, concomitant, or sequential administration of recombinant human interleukin-3 (IL-3) and IL-6 would promote bone marrow regeneration measured by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726b23485a119c1f380ad3f329128ab6
https://doi.org/10.1182/blood.v84.8.2515.bloodjournal8482515
https://doi.org/10.1182/blood.v84.8.2515.bloodjournal8482515
Publikováno v:
Blood. 82:3012-3018
Single cytokine therapy with granulocyte-macrophage colony-stimulating factor (GM-CSF) or interleukin-3 (IL-3) has been shown to be effective in decreasing the respective periods of neutropenia and thrombocytopenia following radiation- or drug-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e14033ba22f3e08e902c5a10780e7d8
https://doi.org/10.1182/blood.v82.10.3012.bloodjournal82103012
https://doi.org/10.1182/blood.v82.10.3012.bloodjournal82103012
Publikováno v:
Blood. 95(3)
Myelopoietins (MPOs) constitute a family of engineered, chimeric molecules that bind and activate the IL-3 and G-CSF receptors on hematopoietic cells. This study investigated the in vivo hematopoietic response of rhesus monkeys administered MPO after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f10e70ac0ea0ce160bd2d512a90dcff5
https://pubmed.ncbi.nlm.nih.gov/10648394
https://pubmed.ncbi.nlm.nih.gov/10648394
Publikováno v:
Transfusion medicine reviews. 11(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aac326a0ab31eb7dca513ddeb19db04a
https://pubmed.ncbi.nlm.nih.gov/9345706
https://pubmed.ncbi.nlm.nih.gov/9345706
Publikováno v:
Blood. 87(10)
Combination cytokine therapy continues to be evaluated in an effort to stimulate multilineage hematopoietic reconstitution after bone marrow myelosuppression. This study evaluated the efficacy of combination therapy with the synthetic interleukin-3 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d596024d36e5ca84142850fbea37127
https://pubmed.ncbi.nlm.nih.gov/8639770
https://pubmed.ncbi.nlm.nih.gov/8639770
Publikováno v:
Blood. 87(2)
The synthetic cytokine (Synthokine) SC-55494 is a high-affinity interleukin-3 (IL-3) receptor ligand that stimulates greater in vitro multilineage hematopoietic activity than native IL-3, while inducing no significant increase in inflammatory activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47f3d3399d3bfbd013c54b8fc124d6e4
https://pubmed.ncbi.nlm.nih.gov/8555480
https://pubmed.ncbi.nlm.nih.gov/8555480
Publikováno v:
Blood. 86(1)
Megakaryocyte growth and development factor (MGDF) is a novel cytokine that binds to the c-mpl receptor and stimulates megakaryocyte development in vitro and in vivo. This report describes the ability of recombinant human (r-Hu) MGDF to affect megaka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f651be1f12997fc46702722b2222701a
https://pubmed.ncbi.nlm.nih.gov/7795256
https://pubmed.ncbi.nlm.nih.gov/7795256
Publikováno v:
Blood. 84(11)
The therapeutic efficacy of recombinant human leukemia inhibitory factor (LIF) was examined in a nonhuman primate model of radiation-induced marrow aplasia. Rhesus monkeys received 450 cGy of total-body, 1:1 mixed neutron:gamma radiation. For 23 days
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::400dc59b7ed7636f9581a0bdfaa4ffd2
https://pubmed.ncbi.nlm.nih.gov/7949122
https://pubmed.ncbi.nlm.nih.gov/7949122