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pro vyhledávání: '"T. J. Jenner"'
Induction of DNA DSBs by low-LET radiations reflects clustered damage produced predominantly by low-energy, secondary electron "track ends". Cell inactivation and induction of DSBs and their rejoining, assayed using pulsed-field gel electrophoresis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2014c97dee42d7eb2657dd7fb0058a93
https://doi.org/10.1667/0033-7587(2001)155[0440:dotyod]2.0.co
https://doi.org/10.1667/0033-7587(2001)155[0440:dotyod]2.0.co
Publikováno v:
Nucleic Acids Research. 32:1602-1609
Clustered DNA damage sites, in which two or more lesions are formed within a few helical turns of the DNA after passage of a single radiation track, are signatures of DNA modifications induced by ionizing radiation in mammalian cells. Mutant hamster
Publikováno v:
International Journal of Radiation Biology. 64:265-273
The induction and rejoining of DNA double-strand breaks (dsbs) in V79-4 mammalian cells following irradiation by 60Co gamma-rays and 238Pu alpha-particles (average LET 120 keV microns-1) under aerobic conditions have been determined using both the su
Publikováno v:
Biochemical Pharmacology. 44:1341-1347
Incubation of the 2-nitroimidazole-aziridine, RSU-1069 [1-(2-nitro-1-imidazolyl)-3-(1-aziridinyl) -2-propanol], and its monomethylaziridine analogue, RSU-1131 [1-(2-nitro-1-imidazolyl)-3-(1-(2-methylaziridinyl))-2-propanol], with V79-4 mammalian cell
Publikováno v:
International Journal of Radiation Biology. 61:631-637
The results reported form part of a series of experiments to substantiate and extend the findings by Belli et al. (1989) that protons are more biologically effective at cell killing than alpha-particles of the same LET. The irradiations were carried
Publikováno v:
Biochemical Pharmacology. 42:1705-1710
The induction and repair of single (ssb) and double (dsb) strand breaks in DNA under aerobic or hypoxic conditions have been determined using sucrose sedimentation techniques following incubation of V79 mammalian cells with RSU-1069 or misonidazole,
Publikováno v:
Nucleic acids research. 30(15)
The signature DNA lesion induced by ionizing radiation is clustered DNA damage. Gamma radiation-induced clustered DNA damage containing base lesions was investigated in plasmid DNA under cell mimetic conditions and in two cell lines, V79-4 (hamster)
Autor:
V A, Randall, N A, Hibberts, M J, Thornton, A E, Merrick, K, Hamada, S, Kato, T J, Jenner, I, de Oliveira, A G, Messenger
Publikováno v:
European journal of dermatology : EJD. 11(4)
Androgens regulate many aspects of human hair growth in both sexes. After puberty they transform tiny vellus follicles in many areas, e.g. the face, to terminal ones producing long, thick, pigmented hairs. In genetically predisposed individuals, andr
Publikováno v:
Radiation research. 150(5)
The induction of DNA-protein crosslinks (DPCs) in Chinese hamster V79-4 cells after irradiation under hypoxic and aerobic conditions at 277 K with 60Co gamma rays, 238Pu alpha particles and aluminum K (Al(K)) ultrasoft X rays has been determined usin
Publikováno v:
Radiation research. 148(4)
Characteristic aluminum K (AlK) (energy of 1.5 keV) and copper L (CuL) (energy of approximately 0.96 keV) ultrasoft X rays have been used to investigate the effectiveness of the numerous low-energy secondary electrons produced by low-linear energy tr