Zobrazeno 1 - 10 of 17 pro vyhledávání: '"T. J. Goldschmidt"'
1
Dextran sulfate sodium (DSS) induced experimental colitis in immunodeficient mice: Effects in CD4+-cell depleted, athymic and NK-cell depleted SCID mice
Autor: L.-G. Axelsson, T. J. Goldschmidt, A. C. Bylund-Fellenius, A. Grönberg, E. Landström
Publikováno v: Inflammation Research. 45:181-191
Administration of dextran sulfate to mice, given in the drinking water results in acute or subacute colonic inflammation, depending on the administration protocol. This colonic inflammation exhibits ulceration, healing and repair, and a therapeutic r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf16b4c37616205c666d8259f1859f1
https://doi.org/10.1007/bf02285159
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2
Host defense against cholera toxin is strongly CD4+ T cell dependent
Autor: E Hörnqvist, Rikard Holmdahl, N Lycke, T J Goldschmidt
Publikováno v: Infection and Immunity. 59:3630-3638
This study investigates the role of CD4+ T cells in host defense against cholera enterotoxin-induced diarrhea. Antitoxin immunoglobulin A formation and gut protection against cholera toxin (CT) following oral immunizations with CT were evaluated in n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd738cb6fca2b2402b25b59f30a334e0
https://doi.org/10.1128/iai.59.10.3630-3638.1991
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4
Therapeutic effects of monoclonal antibodies to alpha beta TCR but not to CD4 on collagen-induced arthritis in the rat
Autor: T J Goldschmidt, Rikard Holmdahl
Publikováno v: Cellular immunology. 154(1)
The role which T cells play in the pathogenesis of the collagen-induced arthritis (CIA) model is not yet fully understood. Although CIA is most likely dependent on the activity of class II-restricted CD4+ T cells, only prophylactic but not therapeuti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7327e6b36e285f42ca22bd4e8567dd28
https://pubmed.ncbi.nlm.nih.gov/7907007
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5
Activated type II collagen reactive T cells are not eliminated by in vivo anti-CD4 treatment. Implications for therapeutic approaches on autoimmune arthritis
Autor: T J Goldschmidt, Rikard Holmdahl, Vivianne Malmström, Mikael Andersson
Publikováno v: Immunobiology. 184(4-5)
Activation of CD4+ T cells plays an important role in type II collagen (CII) induced arthritis (CIA). The CD4+ T cell dependency is demonstrated by anti-CD4 antibody treatment which suppresses CIA in mice if injected before CII immunization. The same
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43585f23c408dd97ef3946e779f1aed
https://pubmed.ncbi.nlm.nih.gov/1350565
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6
Homologous collagen-induced arthritis in rats and mice are associated with structurally different major histocompatibility complex DQ-like molecules
Autor: T J Goldschmidt, Rikard Holmdahl, Kenth Gustafsson, Hans J. Hedrich, Carina Vingsbo, Christina Kvick, Mikael Karlsson
Publikováno v: European Journal of Immunology
Collagen‐induced arthritis (CIA) in rats, induced with homologous type II collagen (CII), is a genetically more restricted disease and has better resemblance to rheumatoid arthritis by its chronic disease course, than CIA induced with heterologous
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2d52967ea51a1ceed782b5707542b1
https://pubmed.ncbi.nlm.nih.gov/1537378
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7
Anti-T cell receptor antibody treatment of rats with established autologous collagen-induced arthritis: suppression of arthritis without reduction of anti-type II collagen autoantibody levels
Autor: T J Goldschmidt, Rikard Holmdahl
Publikováno v: European journal of immunology. 21(5)
Activation of T cells is critical for the development of type II collagen (CII)-induced arthritis (CIA). However, the relative importance of T cells in their delivery of help to B cells, promoting autoantibody formation or acting as inflammatory init
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da1f9a0f946d9a789f0e633cc71edd3
https://pubmed.ncbi.nlm.nih.gov/1828032
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9
In vivo elimination of T cells expressing specific T-cell receptor V beta chains in mice susceptible to collagen-induced arthritis
Autor: T J, Goldschmidt, L, Jansson, R, Holmdahl
Publikováno v: Immunology. 69(4)
Type II collagen-induced arthritis (CIA) is believed to be dependent on T cells expressing a limited number of V beta chains. Two different methods were used to selectively eliminate T cells expressing a certain T-cell receptor (TcR) V beta chain in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93c82722a9aecd77fd23416ced26c1d6
https://pubmed.ncbi.nlm.nih.gov/2139866
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