Zobrazeno 1 - 10
of 84
pro vyhledávání: '"T. J. Chambers"'
Autor:
L. N. Signal, J. Stanley, M. Smith, M. B. Barr, T. J. Chambers, J. Zhou, A. Duane, C. Gurrin, A. F. Smeaton, C. McKerchar, A. L. Pearson, J. Hoek, G. L. S. Jenkin, C. Ni Mhurchu
Publikováno v:
International Journal of Behavioral Nutrition and Physical Activity, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Over the past three decades the global prevalence of childhood overweight and obesity has increased by 47%. Marketing of energy-dense nutrient-poor foods and beverages contributes to this worldwide increase. Previous research on f
Externí odkaz:
https://doaj.org/article/1958108f8357459b86b3d5b5d5ede69a
Publikováno v:
The Journal of Immunology. 157:936-940
IL-10, originally described as a cytokine synthesis inhibitory factor produced by T cells, has recently been found to suppress osteoblastic differentiation in mouse bone marrow cultures. Since osteoblastic cells exert a major influence on the product
Autor:
T. J. Hall, T. J. Chambers
Publikováno v:
Inflammation Research. 45:1-9
In this article we have overviewed recent important advances in understanding the molecular mechanisms involved in osteoclastic bone resorption. Specifically, new findings relating to osteoclast activation and the process of bone resorption are revie
Publikováno v:
The Journal of Immunology. 154:6065-6072
Cells of the osteoblastic lineage play a major role in the regulation of osteoclastic bone resorption. Recent studies have demonstrated production of chemokines by osteoblastic cells. Although these phagocyte-stimulating and proinflammatory cytokines
Publikováno v:
Journal of Virology. 69:1600-1605
The determinants of cleavage site specificity of the yellow fever virus (YF) NS3 proteinase for its 2B/3 cleavage site have been studied by using site-directed mutagenesis. Mutations at residues within the GARR decreases S sequence were tested for ef
Publikováno v:
Journal of Endocrinology. 142:119-125
We have recently found that administration of oestradiol-17β (OE2) to rats stimulates trabecular bone formation. It is not known, however, whether oestrogen has a similar action on bone formation rate under physiological circumstances. Oestrogen is
Autor:
T J, Chambers, K, Fuller
Publikováno v:
Annals of the New York Academy of Sciences. 1240
Although much is known about how osteoclasts are formed, we know little about how they are activated, or how they recognize bone as the substrate appropriate for resorption. Bone mineral is considered to be essential to this recognition process, but
Publikováno v:
Journal of Virology. 67:6797-6807
To study the role of specific regions of the yellow fever virus NS2B protein in proteolytic processing and association with the NS3 proteinase domain, a series of mutations were created in the hydrophobic regions and in a central conserved hydrophili
Autor:
T J, Chambers
Publikováno v:
Annals of the New York Academy of Sciences. 1192
Thirty-five years ago it had become clear that the osteoclast was not a bone cell but an immigrant into bone, derived from the hemopoietic system. Among hemopoietic cells, mononuclear phagocytes seemed the most likely precursors. However, for the pro
Autor:
Robert J. Fletterick, J F Bazan, David W. McCourt, T J Chambers, R C Weir, Charles M. Rice, Arash Grakoui
Publikováno v:
Proceedings of the National Academy of Sciences. 87:8898-8902
Sequence homology and molecular modeling studies have suggested that the N-terminal one-third of the flavirvirus nonstructural protein NS3 functions as a trypsin-like serine protease. To examine the putative proteolytic activity of NS3, segments of t