Zobrazeno 1 - 10
of 929
pro vyhledávání: '"T. Isaacs"'
Autor:
Laura A. Sena, Rajendra Kumar, David E. Sanin, Elizabeth A. Thompson, D. Marc Rosen, Susan L. Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes-Alexandre, Jessica L. Hicks, Tracy Jones, Kiara A. Bowers, Jillian N. Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W. Nathaniel Brennen, Sushant K. Kachhap, Emmanuel S. Antonarakis, Angelo M. De Marzo, John T. Isaacs, Mark C. Markowski, Samuel R. Denmeade
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA),
Externí odkaz:
https://doaj.org/article/1190b8e3606d4217ab6c491c95462033
Autor:
Kathleen T. Isaacs
Enrich your library collection with outstanding informational books that children really want to read. This annotated resource by veteran children's book reviewer Isaacs surveys the best nonfiction/informational titles for ages 3 through 10, helping
Publikováno v:
Ecology and Evolution, Vol 12, Iss 5, Pp n/a-n/a (2022)
Abstract Localizing wildlife contributes in multiple ways to species conservation. Data on animal locations can reveal elements of social behavior, habitat use, population dynamics, and be useful in calculating population density. Acoustic localizati
Externí odkaz:
https://doaj.org/article/187a0edab7f24071b0b6ad9392fcf9f7
Autor:
W. Nathaniel Brennen, Yezi Zhu, Ilsa M. Coleman, Susan L. Dalrymple, Lizamma Antony, Radhika A. Patel, Brian Hanratty, Roshan Chikarmane, Alan K. Meeker, S. Lilly Zheng, Jody E. Hooper, Jun Luo, Angelo M. De Marzo, Eva Corey, Jianfeng Xu, Srinivasan Yegnasubramanian, Michael C. Haffner, Peter S. Nelson, William G. Nelson, William B. Isaacs, John T. Isaacs
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
Resistance to AR signaling inhibitors (ARSis) in a subset of metastatic castration-resistant prostate cancers (mCRPCs) occurs with the emergence of AR– neuroendocrine prostate cancer (NEPC) coupled with mutations/deletions in PTEN, TP53, and RB1 an
Externí odkaz:
https://doaj.org/article/f6df29103c0e46759e5821f89b231584
Publikováno v:
Asian Journal of Urology, Vol 6, Iss 1, Pp 99-108 (2019)
Localized prostate cancer is curable via annihilation of the entire cancer neighborhood by surgery or local radiation. Unfortunately, once metastatic, no available therapy is curative. The vast majority will die despite aggressive systemic combinatio
Externí odkaz:
https://doaj.org/article/298316599c0f45169bd11ccfa803c5ea
Autor:
Timothy E. G. Krueger, Daniel L. J. Thorek, Samuel R. Denmeade, John T. Isaacs, W. Nathaniel Brennen
Publikováno v:
Stem Cells Translational Medicine, Vol 7, Iss 9, Pp 651-663 (2018)
Abstract The development of mesenchymal stem cells (MSCs) as cell‐based drug delivery vectors for numerous clinical indications, including cancer, has significant promise. However, a considerable challenge for effective translation of these approac
Externí odkaz:
https://doaj.org/article/7559fd62178645e6b65db7694242911c
Publikováno v:
Molecules, Vol 26, Iss 24, p 7469 (2021)
Søren Brøgger Christensen isolated and characterized the cell-penetrant sesquiterpene lactone Thapsigargin (TG) from the fruit Thapsia garganica. In the late 1980s/early 1990s, TG was supplied to multiple independent and collaborative groups. Using
Externí odkaz:
https://doaj.org/article/73b6c006ea3d4efd966c5acdc0d1edd1
Publikováno v:
South African Medical Journal, Vol 108, Iss 9, Pp 714-720 (2018)
Tattoos are becoming increasingly common. They have an impact on many aspects of clinician-patient interaction. Therefore, it is necessary for clinicians to have a basic knowledge of pertinent issues relating to tattoos. We provide a brief overview a
Externí odkaz:
https://doaj.org/article/cc605275fafe48168e6abec563544354
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background To combat malaria transmission, the Ugandan government has embarked upon an ambitious programme of indoor residual spraying (IRS) with a carbamate class insecticide, bendiocarb. In preparation for this campaign, we characterized b
Externí odkaz:
https://doaj.org/article/f49a3142e2f94daeafa76f1fcc86b1c9
Autor:
Philip J. Almeter, James T. Isaacs, Aaron N. Hunter, Bradley S. Henderson, Thomas Platt, Billie J. Mitchell, David Do, Alyssa B. Brainard, Joshua E. Brown, Rachael M. Stone, Bao-Han Nguyen, Matthew F. Warren, Smaran A. Bhaktawara, Megan N. Bossle, Lindsey M. Long, Stephanie P. Zapata, Cinnamon R. Larkin, Thomas A. Lyman, Seth A. Larkin, Jonathan A. Labuhn, Jeffrey W. Reynolds, Erin E. Schuler, Ryan W. Naseman, Gary L. Johnson, Robert A. Lodder
Publikováno v:
Journal of Pharmaceutical Innovation. 17:269-282
Since the US Food and Drug Administration (FDA) began monitoring the quality of pharmaceutical manufacturing by enforcing current good manufacturing practices roughly 60 years ago, forces related to the global economy have changed, rendering the task