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Akademický článek

An output-null signature of inertial load in motor cortex

Autor: Eric A. Kirk, Keenan T. Hope, Samuel J. Sober, Britton A. Sauerbrei

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Coordinated movement requires the nervous system to continuously compensate for changes in mechanical load across different conditions. For voluntary movements like reaching, the motor cortex is a critical hub that generates commands to move

Externí odkaz: https://doaj.org/article/c3a532d161bd49098b62cd2589d882ff

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Akademický článek

Editorial: Activated Synapses

Autor: F. Javier Rubio, Emmanuel Valjent, Bruce T. Hope

Publikováno v: Frontiers in Synaptic Neuroscience, Vol 14 (2022)

Externí odkaz: https://doaj.org/article/fc34f775fa9d4b29990347d6cd8e84a8

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Akademický článek

Direct measurement of neuronal ensemble activity using photoacoustic imaging in the stimulated Fos-LacZ transgenic rat brain: A proof-of-principle study

Autor: James I. Matchynski, Rayyan Manwar, Karl J. Kratkiewicz, Rajtarun Madangopal, Veronica A. Lennon, Kassem M. Makki, Abbey L. Reppen, Alexander R. Woznicki, Bruce T. Hope, Shane A. Perrine, Alana C. Conti, Kamran Avanaki

Publikováno v: Photoacoustics, Vol 24, Iss , Pp 100297- (2021)

Measuring neuroactivity underlying complex behaviors facilitates understanding the microcircuitry that supports these behaviors. We have developed a functional and molecular photoacoustic tomography (F/M-PAT) system which allows direct imaging of Fos

Externí odkaz: https://doaj.org/article/849d98a1f58a436b92be66f7d30b5476

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Akademický článek

Anti-relapse neurons in the infralimbic cortex of rats drive relapse-suppression by drug omission cues

Autor: Amanda Laque, Genna L. De Ness, Grant E. Wagner, Hermina Nedelescu, Ayla Carroll, Debbie Watry, Tony M. Kerr, Eisuke Koya, Bruce T. Hope, Friedbert Weiss, Greg I. Elmer, Nobuyoshi Suto

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

Drug addiction is a chronic disorder and many sufferers experience relapses even after a period of successful abstinence. Here, the authors reveal a subset of neurons in the rat infralimbic cortex that suppresses relapse into cocaine or alcohol use b

Externí odkaz: https://doaj.org/article/32e54db896614f8fb088a7ce1dccb649

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Role of Piriform Cortex and Its Afferent Projections in Relapse to Fentanyl Seeking after Food Choice-Induced Voluntary Abstinence

Autor: Sarah M. Claypool, David J. Reiner, Sana Behdin, Javier Orihuel, Ashley Batista, Kiera E. Caldwell, Jonathan J. Chow, Jennifer M. Bossert, F. Javier Rubio, Bruce T. Hope, Yavin Shaham

Publikováno v: The Journal of Neuroscience. 43:2597-2614

We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after food choice-induced voluntary abstinence. Here, we used this model to further study the role of Pir and its afferent projections in fentanyl relapse. We t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::427e41d055dac4bf5f98bbc5ba54c4f2
https://doi.org/10.1523/jneurosci.0034-23.2023

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Akademický článek

Improved methods for marking active neuron populations

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)

Methods to directly label active neurons are still lacking. Here the authors develop CaMPARI2, a photoconvertible fluorescent protein sensor for neuronal activity with improved brightness and calcium binding kinetics, as well as an antibody to amplif

Externí odkaz: https://doaj.org/article/0bc2383719ed4d3a919e09c4acecd7ca

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