Výsledky vyhledávání - "T. H. Porter"

Anticoagulant activity of a naphthoquinone analog of vitamin K and an inhibitor of coenzyme Q10- enzyme systems

Autor: A B, Combs, T H, Porter, K, Folkers

Publikováno v: Research communications in chemical pathology and pharmacology. 13(1)

Synthetic 2-hydroxy-3-h-dodecylmercapto-1,4-naphthoquinone is an analog of both vitamin K1 and coenzyme Q10. This naphthoquinone analog is an effective inhibitor of coenzyme Q10-enzymes of mammalian mitochondria, which are components of electron tran

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48669ff386668d96a898b61eefd04b39
https://pubmed.ncbi.nlm.nih.gov/1257593

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Inhibition of two human tumor cell lines by antimetabolites of coenzyme Q10

Autor: K, Folkers, T H, Porter, J R, Bertino, B, Moroson

Publikováno v: Research communications in chemical pathology and pharmacology. 19(3)

5-Chloro-2,3-dimethyoxy-6-octylmercapto-1,4-benzoquinone (NSC 252188) and 2,3-dimethoxy-5-hydroxy-6-phytyl-1,4-benzoquinone (NSC 277818) inhibited the human cell lines 4265 and K 562c, and the experimental animal tumor line W256; they also showed ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d64109c3de58c0ac0a54536488bfedaa
https://pubmed.ncbi.nlm.nih.gov/653103

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Evaluation of the tinnitus masker

Autor: H E, Maddox, T H, Porter

Publikováno v: The American journal of otology. 2(3)

The disabling symptom of tinnitus has no predictable medical or surgical treatment. In most patients, an examination and suitable explanation or, if needed, hearing aid fitting will dispense with the problem. This article deals with another group of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f07b3839bc28ce44a8cc5fa4ab28a54a
https://pubmed.ncbi.nlm.nih.gov/7282889

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Inhibition of Mycobacterium intracellulare by some vitamin K and coenzyme Q analogues

Autor: P R, Gangadharam, P F, Pratt, P B, Damle, P T, Davidson, T H, Porter, K, Folkers

Publikováno v: The American review of respiratory disease. 118(3)

Because vitamin K is present in several species of mycobacteria, and because coenzyme Q has been found to stimulate the growth of Mycobacterium tuberculosis and atypical mycobacteria, 8 quinones that can be considered to be dual analogues of vitamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0b66256ecaac6ba8dabe572a520d10bb
https://pubmed.ncbi.nlm.nih.gov/707875

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