Zobrazeno 1 - 10
of 28
pro vyhledávání: '"T. H. Gardiner"'
Autor:
Robert W. Kapp, Gary A. Wright, Jonathan Hurley, Heather D. Burleigh-Flayer, Christopher Bevan, Michael W. Gill, T. H. Gardiner, T. R. Tyler
Publikováno v:
Journal of Applied Toxicology. 18:373-381
In a previous subchronic neurotoxicity study, increases in motor activity were observed for female rats after 9 and 13 weeks of exposure to 5000 ppm of isopropanol vapor. The present study was conducted to evaluate the reproducibility of these effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9e0066afad6e557ae6b797b4dbebf71
https://doi.org/10.1002/(sici)1099-1263(1998090)18:5<373::aid-jat522>3.0.co
https://doi.org/10.1002/(sici)1099-1263(1998090)18:5<373::aid-jat522>3.0.co
Autor:
T. H. Gardiner, R. W. Slauter, T. R. Tyler, Lawrence W. Masten, Richard H. McKee, A. R. Jeffcoat, D. P. Coleman, D. E. Strother, N. F. Gaudette
Publikováno v:
Fundamental and Applied Toxicology. 23:407-420
The absorption, metabolism, disposition, and excretion of isopropanol (IPA) were studied in male and female rats and mice. Animals were exposed by i.v. (300 mg/kg) and inhalation (500 and 5000 ppm for 6 hr) routes; additionally, IPA was given by gava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caabd0248f972f665587d3f8f2d04c41
https://doi.org/10.1006/faat.1994.1122
https://doi.org/10.1006/faat.1994.1122
Autor:
R. W. TYL, L. W. MASTEN, M. C. MARR, C. B. MYERS, R. W. SLAUTER, T. H. GARDINER, D. E. STROTHER, R. H. MCKEE, T. R. TYLER
Publikováno v:
Toxicological Sciences. 22:139-151
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::addaf819f76682dccee488ab532d09bb
https://doi.org/10.1093/toxsci/22.1.139
https://doi.org/10.1093/toxsci/22.1.139
Autor:
H. K. BATES, R. H. MCKEE, G. S. BIELER, T. H. GARDINER, M. W. GILL, D. E. STROTHER, L. W. MASTEN
Publikováno v:
Toxicological Sciences. 22:152-158
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1469de5ef49d07db3490ae1c6b9e825
https://doi.org/10.1093/toxsci/22.1.152
https://doi.org/10.1093/toxsci/22.1.152
Autor:
Hudson Bates, Lawrence W. Masten, Michael W. Gill, Richard H. McKee, D. E. Strother, T. H. Gardiner, Gayle Bieler
Publikováno v:
Fundamental and Applied Toxicology. 22:152-158
Isopropanol was administered by gavage to timed-mated rats from Gestation Day (GD) 6 through Postnatal Day (PND) 21. Doses administered were 0, 200, 700, or 1200 mg/kg/day in a volume of 5 ml/kg. The dams were allowed to deliver and body weights and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7677fdcfcadffe47006b0d2f9b47dcfc
https://doi.org/10.1006/faat.1994.1018
https://doi.org/10.1006/faat.1994.1018
Autor:
Melissa C. Marr, Richard H. McKee, Rochelle W. Tyl, Lawrence W. Masten, T. H. Gardiner, T. R. Tyler, D. E. Strother, Christina B. Myers, R. W. Slauter
Publikováno v:
Fundamental and Applied Toxicology. 22:139-151
Developmental Toxicity Evaluation of Isopropanol by Gavage in Rats and Rabbits. Tyl, R. W., Masten, L. W., Marr, M. C., Myers, C. B., Slauter, R. W., Gardiner, T. H., Strother, D. E., McKee, R. H., and Tyler, T. R. (1994). Fundam. Appl. Toxicol. 22,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edbc46875b2f5263dcdaf21b88f07bdb
https://doi.org/10.1006/faat.1994.1017
https://doi.org/10.1006/faat.1994.1017
Publikováno v:
Regulatory Toxicology and Pharmacology. 15:S1-S77
The glycidyloxy compounds constitute an important group of chemicals used extensively in the formulation of epoxy resin systems employed in coatings, electronics, structural composites, and adhesives. Although extensive toxicological data are availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41aa1a9edd4dbfec25c9ac2fedeaef1
https://doi.org/10.1016/0273-2300(92)90075-k
https://doi.org/10.1016/0273-2300(92)90075-k
Autor:
Heather D. Burleigh-Flayer, C. Bevan, D. Neptun, R. Kapp, Gary A. Wright, T. R. Tyler, R. Garman, T. H. Gardiner
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 36(2)
The potential oncogenic effects of isopropanol, a widely used solvent, were investigated. Four groups of animals, each consisting of 75 CD-1 mice/sex and 75 Fischer 344 rats/sex, were exposed to isopropanol vapor (CAS No. 67-63-0) at target concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f8fc5a2e72bbb8db966f50dae825910
https://pubmed.ncbi.nlm.nih.gov/9143479
https://pubmed.ncbi.nlm.nih.gov/9143479
Autor:
D. E. Strother, Lawrence W. Masten, Heather D. Burleigh-Flayer, Michael W. Gill, Richard H. McKee, T. H. Gardiner, T. R. Tyler
Publikováno v:
Journal of applied toxicology : JAT. 15(2)
Five groups of 25 Fischer 344 rats of each sex were exposed for 6 h to isopropanol vapor at 0, 500, 1500, 5000 or 10,000 ppm. Behavioral observations for 10 rats of each sex were made prior to and 1, 6, and 24 h after exposure. Motor activity was eva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de1f2f67ca4b1b2d358310a56082c82
https://pubmed.ncbi.nlm.nih.gov/7782562
https://pubmed.ncbi.nlm.nih.gov/7782562
Autor:
T. H. Gardiner, Robert W. Kapp, T. R. Tyler, B. K. Beyer, Christopher Bevan, Larry S. Andrews
Publikováno v:
Journal of applied toxicology : JAT. 15(2)
A two-generation reproduction toxicity study was conducted in rats with isopropanol. Thirty rats of each sex per group (P1) were dosed once daily by oral gavage with 0, 100, 500 or 1000 mg isopropanol kg-1 for at least 10 weeks prior to mating. Paren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f30a25c0fcc60b3b966fab5396fff66a
https://pubmed.ncbi.nlm.nih.gov/7782556
https://pubmed.ncbi.nlm.nih.gov/7782556